424 completed, 104 terminated, 70 recruiting, 57 unknown. 751 Phase 1, 287 Phase 2.
Follow Paclitaxel: new trials by email Literature Review of Paclitaxel trials Research Report on Paclitaxel
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Futibatinib With Paclitaxel and Ramucirumab for the Treatment of Locally Advanced or Unresectable Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Biospecimen Collection, Computed Tomography, Futibatinib - Clinical Stage II Esophageal Adenocarcinoma AJCC v8, Clinical Stage III Esophageal Adenocarcinoma AJCC v8 | Phase 1 | Not yet recruiting | Northwestern University | 18 | 2027-09-09 | 2026-10-20 |
| Neoadjuvant Inhaled Azacytidine With Platinum-Based Chemotherapy and Durvalumab (MEDI4736) - a Combined Epigenetic-Immunotherapy (AZA-AEGEAN) Regimen for Operable Early-Stage Non-Small Cell Lung Cancer (NSCLC) azacytidine, carboplatin, paclitaxel - Non-small Cell Lung Cancer (NSCLC), Carcinoma, Non-Small Cell Lung | Phase 1 / Phase 2 | Suspended | National Cancer Institute (NCI) | 60 | 2026-11-04 | 2026-10-30 |
| Personalized Cancer Vaccine (PCV) Strategy in Triple Negative Breast Cancer Patients Paclitaxel, Carboplatin, Pembrolizumab - Triple Negative Breast Cancer | Phase 1 | Not yet recruiting | Washington University School of Medicine | 30 | 2026-10-01 | 2026-09-04 |
| Study of Supplemental Arginine With Chemotherapy and Immunotherapy in Platinum Resistant Ovarian, Fallopian Tube, and Peritoneal Cancer (Arginaid®) Oral Arginine, (R-Gene® 10) IV Arginine, Pembrolizumab - Platinum Resistant Ovarian Cancer, Fallopian Tube Cancers | Phase 1 | Not yet recruiting | Rebecca Arend | 24 | 2026-09-01 | 2026-10-15 |
| Systemic Anti-Cancer Therapy Dose Modifications for Individuals With Duffy Null Phenotype Dexamethasone, Bortezomib, LENALIDOMIDE - Multiple Myeloma, Triple Negative Breast Cancer | Phase 1 | Recruiting | Andrew Hantel, MD | 90 | 2026-07-30 | 2026-08-17 |
| Paclitaxel Oral Solution in HER2-Positive Breast Cancer Neoadjuvant Therapy: A Dose-Finding Study Paclitaxel oral solution plus Trastuzumab and Pertuzumab - HER2 + Breast Cancer | Phase 1 / Phase 2 | Recruiting | Liu Shu | 30 | 2026-07-29 | 2026-08-04 |
| A Study to Investigate the Effect of Food on the Bioavailability of Oral Paclitaxel Administered With Encequidar in Participants With Advanced Solid Tumors Oral Paclitaxel in combination with Encequidar tablet - Metastatic Breast Cancer | Phase 1 | Not yet recruiting | Health Hope Pharma | 46 | 2026-05-01 | 2026-05-12 |
| A Phase Ib Clinical Study on the Safety and Efficacy of HC010 Combinations in Advanced Solid Tumors HC010, Paclitaxel, Oxaliplatin - Advanced Solid Tumor Cancer | Phase 1 | Recruiting | HC Biopharma Inc. | 331 | 2026-03-17 | 2026-03-17 |
| SYS6090 Combination Therapy in Advanced Lung Cancer SYS6090 + pemetrexed + platinum-based chemotherapy, SYS6090 + paclitaxel + platinum-based chemotherapy, SYS6090 + docetaxel - Non-Small Cell Lung Cancer, Small Cell Lung Cancer | Phase 1 / Phase 2 | Not yet recruiting | Shanghai JMT-Bio Inc. | 596 | 2026-02-28 | 2026-03-16 |
| CR-001 in Adult Participants With Locally Advanced or Metastatic Solid Tumors CR-001, Paclitaxel, trifluridine and tipiracil - Locally Advanced / Metastatic Solid Tumors | Phase 1 / Phase 2 | Recruiting | Crescent Biopharma, Inc. | 540 | 2026-02-17 | 2026-10-20 |
| A Study of JNJ-90301900 in Combination With Chemoradiation Therapy in Participants With Locally Advanced Head and Neck Squamous Cell Carcinoma JNJ-90301900, Cisplatin, Intensity Modulated Radiation Therapy (IMRT) - Squamous Cell Carcinoma of Head and Neck | Phase 1 | Recruiting | Johnson & Johnson Enterprise Innovation Inc. | 45 | 2026-01-26 | 2026-09-25 |
| Intraperitoneal Paclitaxel With NALIRIFOX for Pancreatic Ductal Adenocarcinoma With Peritoneal Carcinomatosis Paclitaxel, NALIRIFOX - Pancreatic Ductal Adenocarcinoma (PDAC) | Phase 1 | Recruiting | University of Colorado, Denver | 10 | 2025-12-31 | 2026-02-02 |
| CATALINA-4: A Study to Investigate the Safety and Efficacy of TORL-1-23 With Chemotherapy Given Before Initial Surgery in Women With Advanced Stage Ovarian Cancer TORL-1-23 and paclitaxel, TORL-1-23 and carboplatin, TORL-1-23, paclitaxel, and carboplatin - FIGO Stage III and IV Ovarian Cancer, Fallopian Tube Cancers | Phase 1 / Phase 2 | Recruiting | TORL Biotherapeutics, LLC | 60 | 2025-12-10 | 2026-07-13 |
| A Study of LBL-024 in Combination With Paclitaxel ± Bevacizumab for the Treatment of Platinum-resistant Ovarian Cancer LBL-024 for Injection, Paclitaxel injection, Bevacizumab injection - Ovarian Cancer | Phase 1 / Phase 2 | Recruiting | Nanjing Leads Biolabs Co.,Ltd | 180 | 2025-12-02 | 2026-08-13 |
| A Study of SHR-7367 With Anti-tumor Agents in Patients With Solid Tumors SHR-7367 Injection, SHR-1316 Injection, Paclitaxel for Injection - Solid Tumor | Phase 1 / Phase 2 | Recruiting | Shanghai Hengrui Pharmaceutical Co., Ltd. | 100 | 2025-12-02 | 2025-12-19 |
| A Platform Study in Non-Small Cell Lung Cancer (NSCLC) Rilvegostomig, Cisplatin, Carboplatin - Advanced or Metastatic Non-small Cell Lung Cancer | Phase 1 / Phase 2 | Recruiting | AstraZeneca | 152 | 2025-11-24 | 2026-10-28 |
| Testing the Addition of ASTX660 (Tolinapant) to the Usual Chemotherapy Treatment (Paclitaxel With or Without Bevacizumab) in Patients With Recurrent Ovarian Cancer Bevacizumab, Biospecimen Collection, Computed Tomography - Platinum-Refractory Fallopian Tube Carcinoma, Platinum-Refractory Ovarian Carcinoma | Phase 1 / Phase 2 | Withdrawn | National Cancer Institute (NCI) | 2025-10-31 | 2025-06-03 | |
| Nab-Paclitaxel PIPAC in Combination With Paclitaxel and Ramucirumab for the Treatment of Stomach Cancer With Peritoneal Metastases Biopsy, Biospecimen Collection, Computed Tomography - Clinical Stage IVB Gastric Cancer AJCC v8, Metastatic Gastric Adenocarcinoma | Phase 1 | Recruiting | City of Hope Medical Center | 30 | 2025-10-29 | 2025-11-10 |
| A Phase Ib Clinical Study on the Safety and Efficacy of HC010 Combined With Chemotherapy in Lung Cancer HC010, Paclitaxel (Chemotherapy), Pemetrexed - Advanced Solid Tumor Cancer | Phase 1 | Recruiting | HC Biopharma Inc. | 328 | 2025-10-27 | 2026-02-02 |
| A Study of QLC5508 Combinations in Patients With Advanced Solid Tumors QLC5508, QL1706, Cisplatin/ Carboplatin - Advanced Solid Tumor | Phase 1 / Phase 2 | Recruiting | Qilu Pharmaceutical Co., Ltd. | 444 | 2025-10-24 | 2025-12-01 |
Showing 20 of 751. Sign in to see all of them.
Breast Neoplasms (138) · Carcinoma, Non-Small-Cell Lung (121) · Ovarian Neoplasms (100) · Neoplasms (90) · Neoplasm Metastasis (49) · Fallopian Tube Neoplasms (46) · Lung Neoplasms (44) · Stomach Neoplasms (39) · Carcinoma, Ovarian Epithelial (38) · Triple Negative Breast Neoplasms (34) · Esophageal Neoplasms (31) · Squamous Cell Carcinoma of Head and Neck (31) · Endometrial Neoplasms (28) · Colorectal Neoplasms (23) · Head and Neck Neoplasms (21)
National Cancer Institute (NCI) (54) · M.D. Anderson Cancer Center (33) · Memorial Sloan Kettering Cancer Center (21) · AstraZeneca (18) · Merck Sharp & Dohme LLC (14) · Novartis Pharmaceuticals (13) · Genentech, Inc. (12) · Gynecologic Oncology Group (12) · Bristol-Myers Squibb (11) · Washington University School of Medicine (11) · AbbVie (10) · Hoffmann-La Roche (10) · Millennium Pharmaceuticals, Inc. (10) · Amgen (9) · City of Hope Medical Center (8)
United States (507) · China (80) · South Korea (80) · Spain (70) · France (57) · Canada (53) · Japan (43) · United Kingdom (41) · Belgium (40) · Australia (38) · Italy (33) · Taiwan (28) · Netherlands (27) · Germany (26) · Poland (18)
David Cutler, MD (4) · Dean F. Bajorin, MD (3)
PMID 10235156, PMID 10623700, PMID 10628376, PMID 10793106, PMID 11309294, PMID 11331762, PMID 11410496, PMID 11459964, PMID 11533692, PMID 11573045, PMID 11870157, PMID 12056703, PMID 12205100, PMID 12217790, PMID 12241653, PMID 12460789, PMID 12607634, PMID 12631594, PMID 12717353, PMID 12771884, PMID 14555506, PMID 14666038, PMID 14701743, PMID 14751144, PMID 15246197, PMID 15327776, PMID 15367671, PMID 15539915, PMID 15665856, PMID 1581961, PMID 15829966, PMID 15829967, PMID 15905196, PMID 16116597, PMID 16149148, PMID 16170174, PMID 16239238, PMID 16246975, PMID 16357170, PMID 16394300, PMID 16626792, PMID 16631245, PMID 16730134, PMID 16889823, PMID 16912188, PMID 16946210, PMID 16959305, PMID 17140960, PMID 17194908, PMID 17336213
2023 (17), U10CA027469 (11), 2015 (9), 2016 (9), U10CA180868 (8), 2017 (7), 2018 (7), P30CA016672 (6), P30CA033572 (6), 2009 (5), U01CA062502 (5), U01CA076576 (5), U01CA099168 (5), 2014 (4), P30CA043703 (4)