3 recruiting, 1 enrolling by invitation. 4 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 4 | Recruiting 3, Enrolling by invitation 1 |
Follow Osilodrostat: new trials by email Literature Review of Osilodrostat trials Research Report on Osilodrostat
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Osilodrostat in Patients With Hypertension Caused by Hypercortisolaemia Due to Cushing's Syndrome Osilodrostat, Placebo - Hypertension, Hypercortisolemia | Phase 4 | Recruiting | RECORDATI GROUP | 63 | 2026-08-26 | 2026-10-28 |
| Combination Osilodrostat and Cabergoline in Cushing's Disease osilodrostat, osilodrostat and cabergoline - Cushing Disease Due to Increased ACTH Secretion | Phase 4 | Enrolling by invitation | University of Basrah | 50 | 2026-05-11 | 2026-05-22 |
| Isturisa Treatment in Mild Autonomous Cortisol Secretion( MACS) Osilodrostat (Isturisa) - Mild Autonomous Cortisol Secretion (MACS) | Phase 4 | Recruiting | Johns Hopkins University | 10 | 2026-02-02 | 2026-10-23 |
| Metyrapone Versus Osilodrostat in Patients With Metabolic Autonomous Cortisol Secretion (MACS) Metyrapone 250 mg Oral Tablets, Osilodrostat 1 MG, adrenalectomy - Mild Autonomous Cortisol Secretion (MACS) | Phase 4 | Recruiting | Laikο General Hospital, Athens | 150 | 2025-12-01 | 2025-12-05 |
Hypertension (3) · ACTH Syndrome, Ectopic (2) · Adrenal Hyperplasia, Congenital (1) · Adrenal Insufficiency (1) · Cushing Syndrome (1) · Hyperandrogenism (1) · Hypokalemia (1) · Pituitary ACTH Hypersecretion (1)
Johns Hopkins University (1) · Laikο General Hospital, Athens (1) · RECORDATI GROUP (1) · University of Basrah (1)
United States (2) · Greece (1) · Iraq (1)
Abbas A Mansour (1) · Amir Hamrahian, MD (1) · Haider A Alidrisi (1) · Ibrahim H Hussein, MD (1) · Irina Bancos, MD (1)
PMID 27454103, PMID 28887710, PMID 29510982, PMID 30817193, PMID 31206616, PMID 35220871, PMID 3536461, PMID 35817047, PMID 36952249, PMID 37318239, PMID 37801655, PMID 39062179, PMID 39086899, PMID 6135282
2025 (1)