7 completed, 2 not yet recruiting, 2 recruiting, 2 unknown. 8 Not applicable, 1 Phase 1, 1 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 8 | Completed 3, Not yet recruiting 2, Unknown 2, Recruiting 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
| Phase 4 | 1 | Completed 1 |
Follow OFA: new trials by email Literature Review of OFA trials Research Report on OFA
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Opioid-Free Analgesia for Laparoscopic Cholecystectomy EOI with OFA, OFA - Analgesia After Laparoscopic Cholecystectomy | Not applicable | Not yet recruiting | Assiut University | 70 | 2026-10-15 | 2026-08-06 |
| Opioid-free Anesthesia as an Alternative to General Anesthesia in Patients Undergoing Duodenopancreatic Surgery by Laparotomy. Opioid, OFA - Pain Management | Not applicable | Recruiting | Jagiellonian University | 200 | 2026-09-02 | 2026-09-04 |
| Effect of Opioid-Free Versus Opioid-Based Anesthesia in Discectomy Surgery Dexmedetomidine and Ketamine-based Opioid-free Anesthesia, Fentanyl-based Opioid Anesthesia - Postoperative Pain Intensity | Not applicable | Completed | Zagazig University | 46 | 2026-01-15 | 2026-08-26 |
| Opioid Free and Opioid Based Anesthesia in Elective Lumbar Spine Surgery Opioid-free Anesthesia, Erector Spinae Plane Block, Opioid based Anesthesia - Lumbar Spinal Stenosis, Lumbar Disc Herniation With Radiculopathy | Recruiting | Marmara University | 75 | 2025-12-09 | 2026-03-23 | |
| Non-opioid Anesthesia Based on Thoracic Paravertebral Block During Laparoscopic Sleeve Gastrectomy Levobupivacaine, Dexamethasone contained in the solution for thoracic paravertebral block, Adrenaline - Obese Patients, Bariatric Surgical Pain | Not applicable | Not yet recruiting | IVO JURISIC | 36 | 2025-07-30 | 2025-07-24 |
| A Comparative Study Between Opioids Free Anesthesia and Opioid Anesthesia in Patients With Supratentorial Tumor Resection OFA, OA - Supra-tentorial Tumor | Not applicable | Completed | Kasr El Aini Hospital | 86 | 2025-03-01 | 2025-12-16 |
| Opioid Free Versus Opioid Based General Anesthesia in Septoplasty Under Nociception Level Guidance OFA - Deviated Septum, Opioid Free Anesthesia | Completed | Democritus University of Thrace | 150 | 2024-01-01 | 2026-08-26 | |
| Opioid-free Vs Traditional Balanced Anesthesia in Laparoscopic Colorectal Surgery Opioid free anesthesia, Opioid based Anesthesia - Colorectal Surgery | Phase 3 | Completed | Unai Ortega Mera | 120 | 2022-05-15 | 2024-10-30 |
| Effect of OFA in Laparoscopic Gastrectomy OFA, Control - Postoperative Pain | Not applicable | Completed | Gangnam Severance Hospital | 120 | 2021-09-14 | 2023-01-23 |
| Opioid Free VS Opioid Anesthesia for Craniotomies Opioid free anesthetics, Opioid Anesthetics - Supratentorial Neoplasms | Phase 1 | Completed | Kasr El Aini Hospital | 60 | 2021-07-05 | 2021-10-19 |
| Opioid-free Anesthesia in VATS Lung Resection Paravertebral block+Anterior serratus plane block, opioid free anesthesia, opioid based anesthesia - Opioid Free Anesthesia | Not applicable | Unknown | Peking University People's Hospital | 100 | 2020-08-01 | 2020-08-11 |
| Opioid-free Anesthesia and Acute Postoperative Pain OFA, OBA - Anesthesia, Postoperative Pain | Not applicable | Unknown | Attikon Hospital | 200 | 2019-08-01 | 2021-08-13 |
| Opioid Free Anesthesia: What About Patient Comfort? OFA - Anesthesia | Phase 4 | Completed | Université Libre de Bruxelles | 66 | 2014-09-01 | 2016-08-29 |
Pain, Postoperative (4) · Pain (3) · Agnosia (1) · Cognitive Dysfunction (1) · Intervertebral Disc Degeneration (1) · Postoperative Nausea and Vomiting (1) · Spinal Stenosis (1) · Supratentorial Neoplasms (1) · Visceral Pain (1)
Kasr El Aini Hospital (2) · Assiut University (1) · Attikon Hospital (1) · Democritus University of Thrace (1) · Gangnam Severance Hospital (1) · IVO JURISIC (1) · Jagiellonian University (1) · Marmara University (1) · Peking University People's Hospital (1) · Unai Ortega Mera (1) · Université Libre de Bruxelles (1) · Zagazig University (1)
Egypt (3) · Greece (2) · Belgium (1) · China (1) · Croatia (1) · Poland (1) · South Korea (1) · Spain (1) · Turkey (Türkiye) (1)
Dr Asmaa Mohamed Galal Eldin, Assist Prof (1) · Feng Yi, MD,PhD (1) · Rania S Fahmy (1) · Rania Samir, professor (1) · Seham Seham Moeen, M.D. (1) · Unai Ortega, MD (1)