3 completed, 2 recruiting, 1 active not recruiting, 1 unknown. 7 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 7 | Completed 3, Recruiting 2, Active not recruiting 1, Unknown 1 |
Follow Occlusal Splints: new trials by email Literature Review of Occlusal Splints trials Research Report on Occlusal Splints
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Comparative Effectiveness Study of Positive Airway Pressure (PAP) Therapy, Dental Device, and Atomoxetine-Oxybutynin for Treatment of Obstructive Sleep Apnea in Adults Positive airway pressure (PAP) therapy, Sleep dental device, Atomoxetine-oxybutynin - Obstructive Sleep Apnea (OSA) | Phase 4 | Recruiting | Sairam Parthasarathy | 2400 | 2026-09-04 | 2026-10-19 |
| Occlusal Splint Combined With Granisetron Injection for Management of Myofascial Pain Related to Temporomandibular Disorders Granisetron, lidocaine, occlusal splint - TMD, TMD/Orofacial Pain | Phase 4 | Active not recruiting | Mansoura University | 48 | 2026-01-27 | 2026-03-05 |
| EMG-Based Evaluation of Occlusal Splint and Masseter Botox Effects on Head and Neck Muscles Botulinum toxin injection, Occlusal splint, Botulinum toxin + Occlusal splint combined - Myofascial Pain Syndrome (MPS), Masticatory Muscle Pain | Phase 4 | Recruiting | Istanbul University | 56 | 2025-09-01 | 2025-07-24 |
| First Line Obstructive Sleep Apnea Treatment Study Mandibular advancement device (MAD), Continuous positive airway pressure (CPAP) - Obstructive Sleep Apnea | Phase 4 | Completed | University Hospital, Antwerp | 136 | 2021-11-09 | 2025-02-14 |
| Botox vs Occlusal Splint for Masseter Pain Botox Injectable Product, Occlusal splint - Pain, Face | Phase 4 | Completed | Federal University of Pelotas | 60 | 2018-03-15 | 2021-05-20 |
| ORal ApplianCes for sLeep Apnea of the Elderly Mandibular advancement device, Placebo - Obstructive Sleep Apnea, Hypertension | Phase 4 | Unknown | Hospital de Clinicas de Porto Alegre | 500 | 2014-07-01 | 2016-03-03 |
| PROMAD: Predicting Therapeutic Outcome of Mandibular Advancement Device Treatment in Obstructive Sleep Apnea Mandibular Advancement Device ( MAD) - Obstructive Sleep Apnea Syndrome | Phase 4 | Completed | ethisch.comite@uza.be | 100 | 2012-02-01 | 2021-01-20 |
Sleep Apnea, Obstructive (4) · Facial Pain (2) · Bruxism (1) · Cardiovascular Diseases (1) · Hypertension (1) · Myofascial Pain Syndromes (1) · Temporomandibular Joint Disorders (1)
Federal University of Pelotas (1) · Hospital de Clinicas de Porto Alegre (1) · Istanbul University (1) · Mansoura University (1) · Sairam Parthasarathy (1) · University Hospital, Antwerp (1) · ethisch.comite@uza.be (1)
Belgium (2) · Brazil (2) · Egypt (1) · Turkey (Türkiye) (1) · United States (1)
Denis Martinez, MD, PhD (1) · Sairam Parthasarathy, MD (1) · Sarah A Elmaghraby, Lecturer (1)
PMID 26402736, PMID 31482830, PMID 32267227, PMID 32946702, PMID 34608859, PMID 39510242, PMID 39593526