20 completed, 9 recruiting, 9 unknown, 3 terminated. 39 Not applicable, 2 Phase 3, 1 Early Phase 1, 1 Phase 1, 1 Phase 2.
Follow Negative Pressure Wound Therapy: new trials by email Literature Review of Negative Pressure Wound Therapy trials Research Report on Negative Pressure Wound Therapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Disposable Negative Pressure Wound Therapy Device (SNaP) to Promote Wound Healing in the Lower Limbs Following Mohs Micrographic Surgery for Non-melanoma Skin Cancer Best Practice, Educational Intervention, Electronic Health Record Review - Skin Carcinoma | Not applicable | Not yet recruiting | Jonsson Comprehensive Cancer Center | 60 | 2026-12-01 | 2026-07-01 |
| Treating Emergency Laparotomy Incisions With Negative Pressure Wound Therapy Negative pressure wound therapy, Standard postoperative dressing - Surgical Incision, Wound Dehiscence | Not applicable | Recruiting | Uppsala University | 720 | 2025-12-16 | 2026-07-07 |
| Irrigating vs Traditional Negative Pressure Wound Therapy to Treat Necrotizing Soft Tissue Infections Negative Pressure Wound Therapy, Negative Pressure Wound Therapy with Instillation - Necrotizing Soft Tissue Infections | Not applicable | Recruiting | HealthPartners Institute | 30 | 2025-08-01 | 2025-09-17 |
| Evaluation of Combinational Use of Negative Pressure Wound Therapy (NPWT) for Diabetic Foot Wounds Negative Pressure Wound Therapy, Kerecis, Delayed primary closure with local flap - Diabetic Foot Ulcer | Not applicable | Recruiting | Singapore General Hospital | 75 | 2025-07-22 | 2025-07-25 |
| Prophylactic Negative Pressure Wound Therapy in Laparotomy Wounds: A Randomized Clinical Trial Negative Pressure Wound Therapy, Standard Antibiotic Treatment - Wound, Infection Prevention | Not applicable | Recruiting | Dr Hamail Khanum | 70 | 2025-03-25 | 2025-05-06 |
| Treatment of Full-Thickness Wounds: NPWT Combined With Type-I Collagen Based Advanced Skin Substitute Versus NPWT Alone High Purity Type-I Collagen based Skin Substitute, Negative Pressure Wound Therapy - Full Thickness Skin Defects, Ulcer | Not applicable | Completed | Adichunchanagiri Institute of Medical Sciences, B G Nagara | 104 | 2025-03-15 | 2025-11-21 |
| Compare Stoma Reversal Wound Outcomes Between NPWT and Secondary Intention Healing Negative Pressure Wound Therapy - Negative-Pressure Wound Therapy, Wound Heal | Not applicable | Completed | Maryam Arbab | 72 | 2025-02-24 | 2026-09-23 |
| Regenn® Therapy System Safety Study Regenn® Negative Pressure Therapy System, Prevena™ Incision Management System - Surgical Wound | Phase 1 | Active not recruiting | Progenerative Medical, Inc | 30 | 2024-10-09 | 2026-08-27 |
| ENVELOP: Wound Care Following Pilonidal Sinus Surgery Negative Pressure Wound Therapy, Standard wound care - Pilonidal Sinus, Wound Healing | Not applicable | Recruiting | Royal College of Surgeons, Ireland | 200 | 2024-10-01 | 2026-09-24 |
| Negative Pressure Wound Therapy in Oral Surgery Negative Pressure Wound Therapy, Sham Therapy - Edema, Postoperative Pain | Not applicable | Completed | Tokat Gaziosmanpasa University | 34 | 2024-04-18 | 2025-01-03 |
| PINTA - Prophylactic Incisional Negative Pressure Therapy for Major Amputations Negative Pressure Wound Therapy, Standard Wound Dressing - Wound Surgical, Wound Infection | Not applicable | Recruiting | Royal College of Surgeons, Ireland | 728 | 2024-03-01 | 2026-07-21 |
| Routine Use of Negative Pressure Wound Therapy THR TKR RCT negative pressure wound therapy, standard dressing - Knee Arthropathy, Hip Arthropathy | Not applicable | Recruiting | Chinese University of Hong Kong | 82 | 2023-12-11 | 2023-12-29 |
| Antibiotic Cement Bead Pouch Versus Negative Pressure Wound Therapy Antibiotic Cement Bead Pouch, Negative Pressure Wound Therapy - Open tíbia Fracture | Phase 3 | Recruiting | University of Maryland, Baltimore | 312 | 2023-11-05 | 2026-10-22 |
| NPWT for Abdominal Incisions in DIEP Reconstructions: A RCT Negative Pressure Wound Therapy - Breast Cancer, Surgical Site Infection | Not applicable | Withdrawn | Western University, Canada | 2023-09-01 | 2023-04-19 | |
| PROPEL-2: Prophylactic Negative Pressure Wound Therapy in Laparotomy Wounds Negative Pressure Wound Therapy, Standard wound dressing - Wound Surgical, Wound Infection | Not applicable | Active not recruiting | Royal College of Surgeons, Ireland | 2000 | 2023-07-14 | 2026-07-21 |
| EvaLuating negAtive pressUre Wound theRapy in brEast coNserving Surgery Negative pressure wound therapy - Breast Cancer, Seroma | Not applicable | Unknown | Zuyderland Medisch Centrum | 300 | 2023-05-01 | 2023-07-07 |
| Effectiveness of Negative Pressure Wound Therapy Dressing on Split-Thickness Skin Graft Donor Site Wound Healing Negative Pressure Wound therapy, conventional dressing - Split-thickness Skin Graft Donor Sites, Wound Healing | Not applicable | Completed | Mahmoud Abdalla Hifny Taha | 12 | 2023-01-01 | 2026-06-05 |
| NPWT in Patients Undergoing Surgical Procedures for Management of GI Malignancies Negative Pressure Wound Therapy - Surgical Wound Infection | Phase 2 / Phase 3 | Completed | H. Lee Moffitt Cancer Center and Research Institute | 290 | 2021-08-05 | 2026-06-09 |
| Stent Therapy Versus Endoscopic Vacuum Therapy for Anastomotic Leaks After Esophagectomy EsoSponge, Self-Expanding Metal Stent - Leaks, Anastomotic | Unknown | University Hospital of Cologne | 40 | 2021-05-01 | 2021-04-29 | |
| A Randomized Controlled Trial Evaluating the Role of Negative Pressure Wound Therapy (NPWT) for Incisional Surgical Site Infections in Patients Undergoing Hepatopancreatobiliary Surgery Negative Pressure Wound Therapy - Hepatobiliary Disease, Hepatobiliary Disorders | Not applicable | Completed | Murk Niaz | 46 | 2021-03-06 | 2022-08-01 |
Showing 20 of 47. Sign in to see all of them.
Surgical Wound Infection (13) · Surgical Wound (6) · Wounds and Injuries (6) · Wound Infection (5) · Breast Neoplasms (4) · Diabetic Foot (4) · Infections (3) · Obesity (3) · Seroma (3) · Diabetes Mellitus (2) · Pressure Ulcer (2) · Anastomotic Leak (1) · Cicatrix (1) · Cross Infection (1) · Digestive System Diseases (1)
Royal College of Surgeons, Ireland (3) · University of Witten/Herdecke (3) · Odense University Hospital (2) · Zuyderland Medisch Centrum (2) · Adichunchanagiri Institute of Medical Sciences, B G Nagara (1) · Assiut University (1) · Beijing Chao Yang Hospital (1) · Central Finland Hospital District (1) · Chinese University of Hong Kong (1) · Dow University of Health Sciences (1) · Dr Hamail Khanum (1) · Duke University (1) · First Affiliated Hospital, Sun Yat-Sen University (1) · H. Lee Moffitt Cancer Center and Research Institute (1) · HealthPartners Institute (1)
United States (16) · Canada (4) · Germany (4) · Pakistan (4) · Ireland (3) · Belgium (2) · Denmark (2) · Netherlands (2) · China (1) · Egypt (1) · Finland (1) · Hong Kong (1) · India (1) · Singapore (1) · Sweden (1)
Adam Power, MD (1) · Brian S Myer, MD (1) · Carol Bowen-Wells, MD (1) · Claire Donohoe, PhD, FRCSI (1) · Dan Blazer, MD (1) · Daniel Anaya, MD (1) · Doerthe Seidel (1) · Edward H Chang (1) · Jack Kian Ch'ng (1) · Jeremy C Davis (1) · Jiayuan Zhu, Doctor (1) · Jose M Pimiento, MD (1) · Juha Paloneva, professor (1)
PMID 26223227, PMID 28705547, PMID 29218673, PMID 29653446, PMID 29984413, PMID 30111378, PMID 30374816, PMID 30499799, PMID 31049889, PMID 31503147, PMID 32209619, PMID 32293657, PMID 33953312, PMID 34078426, PMID 36161796, PMID 36180953, PMID 36304071, PMID 36503505, PMID 36728375, PMID 37353654, PMID 39178168, PMID 41291693, PMID 42082225
P30CA016672 (1), U01CK000557 (1)