11 completed, 4 unknown, 3 withdrawn, 1 active not recruiting. 7 Phase 4, 5 Not applicable, 3 Phase 2, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 7 | Completed 5, Active not recruiting 1, Withdrawn 1 |
| Not applicable | 5 | Completed 2, Unknown 2, Withdrawn 1 |
| Phase 2 | 3 | Terminated 1, Unknown 1, Withdrawn 1 |
| Phase 3 | 3 | Completed 2, Unknown 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Scheduled or as Needed Pain Regimen? Motrin and narcotic - Pain, Postoperative | Phase 4 | Active not recruiting | Cape Fear Valley Health System | 90 | 2024-08-01 | 2026-10-21 |
| Evaluation of the Analgesic Efficacy of Multimodal Pain Control Regimens That Aim to Limit the Use of Narcotics in Cholecystectomy and Hernia Repairs Pain control regimens - Acute Pain | Unknown | Methodist Health System | 50 | 2023-02-01 | 2024-03-27 | |
| Dexmedetomidine Versus Magnesium Sulfate in Ultrasound Guided Bilateral Bi-level Erector Spinae Plane Block in Corrective Scoliosis Surgery Dexmedetomidine, Magnesium sulfate, Narcotic Analgesics - Anesthesia , Analgesia | Phase 3 | Completed | Ain Shams University | 60 | 2023-01-05 | 2024-07-30 |
| Ultrasound Guided Psoas Compartment Block vs Suprainguinal Fascia Iliaca Compartment Block Fentanyl, Propofol, Rocuronium - Pain, Postoperative, Hip Dysplasia | Not applicable | Unknown | Tanta University | 85 | 2022-09-29 | 2022-09-30 |
| Efficacy of Steroids on Functional Outcomes After Musculoskeletal Injuries of the Hand Methylprednisolone Tablet, Standard Mobilization Treatment - Hand Injuries, Finger Injuries | Phase 2 / Phase 3 | Unknown | Robert Wood Johnson Barnabas Health | 60 | 2021-09-01 | 2021-08-12 |
| Multi-Modal Anesthesia Protocol in Pain Management of Patients Undergoing Posterior Lumbar Spinal Fusion Surgery Toradol, Morphine, Orphenadrine - Pain Management, Posterior Spinal Fusion | Phase 4 | Completed | University of Puerto Rico | 100 | 2021-04-05 | 2022-06-10 |
| Continuous Erector Spinea Block Versus Intravenous Analgesia in Coronary Bypass Surgery continous erector spinea block, intravenous narcotics - Erector Spinea Block in Open Heart Surgery | Not applicable | Completed | Ain Shams University | 60 | 2019-03-18 | 2021-01-15 |
| Bupivacaine Versus Liposomal Bupivacaine For Breast Pain Management After Breast Recontruction Liposomal Bupivacaine, Bupivacaine, Patient-Controlled Analgesia Pump - Breast Cancer | Phase 2 | Withdrawn | Case Comprehensive Cancer Center | 2018-03-30 | 2020-07-22 | |
| Signs and Symptoms of Opioid-associated Iatrogenic Withdrawal in Critically Ill Adults Opioids - Substance Withdrawal Syndrome | Completed | Marc M. Perreault | 29 | 2018-02-26 | 2025-01-01 | |
| Patient Narcotic Requirements After Outpatient Otolaryngology Procedures Norco, Ibuprofen - Outpatient Surgery, Pain, Postoperative | Phase 3 | Completed | Loma Linda University | 185 | 2018-02-21 | 2022-03-16 |
| Ketamine vs Hydromorphone Ketamine, Narcotics, pain scale - Laparoscopic Gastric Bypass, Obesity | Phase 4 | Completed | University of Florida | 54 | 2017-02-22 | 2021-03-09 |
| Effects of Low Dose Neuromuscular Blocker Usage on Laryngeal Mask Application Rocuronium Bromide, Saline Solution, Fentanyl - Anesthesia | Not applicable | Unknown | TC Erciyes University | 96 | 2017-01-04 | 2018-06-13 |
| Ketamine in Colorectal Surgery Placebo, Ketamine, Acetaminophen - Acute Pain, Pain, Postoperative | Phase 4 | Withdrawn | Medical College of Wisconsin | 2016-07-01 | 2017-10-26 | |
| Narcotic vs. Non-narcotic Pain Study Protocol Narcotic, non-narcotic - Carpal Tunnel | Phase 4 | Completed | Horizon Health Network | 347 | 2016-03-01 | 2022-03-11 |
| Ketamine Infusion Therapy for the Management of Acute Pain in Adult Rib Fracture Patients Ketamine, Placebo, Intercostal Nerve Block - Wounds and Injuries, Rib Fractures | Phase 4 | Completed | Medical College of Wisconsin | 153 | 2015-09-01 | 2020-02-05 |
| Opioids Withdrawal Syndrome in Critically Ill Patients: a Multicenter Prospective Cohort Study Opiates - Substance Withdrawal Syndrome | Completed | Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal | 54 | 2015-01-01 | 2016-02-19 | |
| A Prospective Trial to Reduce Post-Operative Pain in Implant Based Breast Reconstruction Bupivacaine, Botulinum Toxins, Analgesics - Post-operative Pain | Phase 2 | Terminated | Yale University | 2 | 2014-04-01 | 2017-04-10 |
| Ultrasound Guidance for Interscalene Brachial Plexus Block Ultrasound-guided continuous interscalene brachial plexus block, Continuous interscalene brachial plexus block using electrical nerve stimulation, Ropivacaine - Shoulder, Orthopedic Surgery | Phase 4 | Completed | University of Parma | 50 | 2008-05-01 | 2009-11-16 |
| Bimodal Analgesia as Form of Pain Control Post Long Bone Fracture Narcotics alone, Narcotics and NSAIDS - Tibia Fracture, Femur Fracture | Not applicable | Withdrawn | Beth Israel Deaconess Medical Center | 2005-10-01 | 2017-03-22 | |
| Neuraxial Versus Systemic Analgesia for Latent Phase Labor Effect on Rate of Operative Delivery combined spinal epidural analgesia, late analgesia (systemic) - Labor Pain, Pregnancy | Not applicable | Completed | Northwestern University | 1026 | 2001-10-01 | 2014-04-14 |
Pain, Postoperative (7) · Agnosia (6) · Acute Pain (3) · Breast Neoplasms (2) · Pain (2) · Substance Withdrawal Syndrome (2) · Femoral Fractures (1) · Finger Injuries (1) · Fractures, Bone (1) · Hand Injuries (1) · Hip Dislocation (1) · Humeral Fractures (1) · Labor Pain (1) · Median Neuropathy (1) · Obesity (1)
Ain Shams University (2) · Medical College of Wisconsin (2) · Beth Israel Deaconess Medical Center (1) · Cape Fear Valley Health System (1) · Case Comprehensive Cancer Center (1) · Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal (1) · Horizon Health Network (1) · Loma Linda University (1) · Marc M. Perreault (1) · Methodist Health System (1) · Northwestern University (1) · Robert Wood Johnson Barnabas Health (1) · TC Erciyes University (1) · Tanta University (1) · University of Florida (1)
United States (11) · Canada (3) · Egypt (3) · Italy (1) · Puerto Rico (1) · Turkey (Türkiye) (1)
Thomas W Carver, MD (2) · Anne Julie Frenette, M.Sc. (1) · Brian Katt, MD (1) · Carrie Y Peterson, MD (1) · Cynthia A Wong, MD (1) · David M Smyth, MSN (1) · David Williamson, Ph.D. (1) · Donald Lalonde, MD (1) · Giorgio Danelli, MD (1) · Jared Inman, MD (1) · Joshua Trussell, MD (1) · Kelly Van Fossen, DO (1) · Lars C Richardson, MD (1) · Marc M Perreault, PharmD (1)