12 completed, 4 recruiting, 2 not yet recruiting, 1 unknown. 5 Not applicable, 4 Phase 4, 3 Early Phase 1, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Completed 2, Not yet recruiting 1, Recruiting 1, Unknown 1 |
| Phase 4 | 4 | Completed 3, Not yet recruiting 1 |
| Early Phase 1 | 3 | Completed 2, Recruiting 1 |
| Phase 1 | 1 | Completed 1 |
Follow Microdialysis: new trials by email Literature Review of Microdialysis trials Research Report on Microdialysis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Antibiotic Tissue Penetration and Tissue Response in Head and Neck Infection and Reconstructive Surgery Cefuroxime, Dicloxacillin, Cloxacillin - Surgical Wound Infection, Neck Infection | Phase 4 | Not yet recruiting | Tejs Ehlers Klug | 16 | 2026-10-01 | 2026-10-26 |
| Antibiotics Distribution Study in Peripheral Compartments: Contribution of Microdialysis Microdialysis probe placement, Microdialysis and Plasma samples - Children in Cardiac Intensive Care Requiring Surgery for Congenital Heart Disease | Not applicable | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 10 | 2026-01-01 | 2026-01-08 |
| Intratumoral Extracellular Metabolic Impact of DFMO and AMXT 1501 in Patients With Diffuse or High Grade Glioma Biospecimen Collection, Computed Tomography, Eflornithine - Diffuse Glioma, Malignant Glioma | Early Phase 1 | Recruiting | Mayo Clinic | 18 | 2023-10-01 | 2025-11-04 |
| Cerebral Protection in Aortic Arch Surgery Microdialysis - Aortic Aneurysm, Aortic Dissection | Recruiting | Barts & The London NHS Trust | 40 | 2023-07-19 | 2026-09-08 | |
| Tissue Penetration of Antibiotics in CriTically Ill Children Pharmacokinetic sampling (Microdialysis and blood sampling) - Pediatric Critical Illness, Critical Illness | Recruiting | University Hospital, Ghent | 60 | 2021-10-01 | 2026-09-16 | |
| Feasibility of Intra- and Post-operative Microdialysis During Neurosurgery for Central Nervous System Lesions Microdialysis, Magnetic Resonance Imaging, Computed Tomography - Glioma, Glioblastoma | Not applicable | Recruiting | Mayo Clinic | 100 | 2020-01-01 | 2026-08-18 |
| Clinical Protocol of Sensitized Acupoint Changes in Knee Osteoarthritis Patients microdialysis - Microdialysis | Completed | Chinese Medical Association | 33 | 2018-06-01 | 2020-02-12 | |
| Muscle Lactate and Lactate to Pyruvate Ratio Clearance in Septic Shock Patients microdialysis - Septic Shock | Not applicable | Completed | Military Hospital of Tunis | 73 | 2018-01-01 | 2021-04-20 |
| Developing and Validating Blood and Imaging BIOmarkers of AXonal Injury Following Traumatic Brain Injury MRI, Blood Sampling, Microdialysis - Traumatic Brain Injury | Completed | Imperial College London | 313 | 2017-11-30 | 2022-03-31 | |
| Neuropharmacokinetics of Eribulin Mesylate in Treating Patients With Primary or Metastatic Brain Tumors Therapeutic Conventional Surgery, Biopsy, Eribulin Mesylate - Metastatic Malignant Neoplasm in the Adult Brain, Primary Brain Tumor | Early Phase 1 | Completed | City of Hope Medical Center | 8 | 2015-09-16 | 2026-10-13 |
| Cerebral Energy State in Cardiac Surgery Microdialysis - Postoperative; Dysfunction Following Cardiac Surgery | Not applicable | Completed | Odense University Hospital | 10 | 2015-02-01 | 2016-07-27 |
| Impact of Prewarming on Perioperative Body Core Temperature and the Outcomes of Cytoreductive- and Major Open Abdominal Surgery: A Randomised Trial Prewarming, Microdialysis - Hypothermia | Not applicable | Unknown | Charite University, Berlin, Germany | 48 | 2015-02-01 | 2015-02-20 |
| Mediators of Abnormal Reproductive Function in Obesity (MARO) Microdialysis, Vascepa - Fish Oil, Aspirin - Infertility, Female, Obesity | Early Phase 1 | Completed | University of Colorado, Denver | 10 | 2013-03-01 | 2015-03-17 |
| Bafetinib in Treating Patients With Recurrent High-Grade Glioma or Brain Metastases bafetinib, microdialysis, pharmacological study - Adult Anaplastic Astrocytoma, Adult Anaplastic Ependymoma | Phase 1 | Completed | City of Hope Medical Center | 7 | 2010-12-01 | 2018-04-17 |
| Assessment of Target Site Pharmacokinetics of Voriconazole in Healthy Volunteers During Sequence Therapy Voriconazole, microdialysis - Healthy | Phase 4 | Completed | Martin-Luther-Universität Halle-Wittenberg | 9 | 2009-02-01 | 2013-11-01 |
| Target Site Pharmacokinetics of Ertapenem After Multiple Doses in Diabetes Patients With Soft Tissue Infection Microdialysis - Soft Tissue Infection | Phase 4 | Completed | Medical University of Vienna | 10 | 2008-02-01 | 2011-08-09 |
| Investigation of Correlation Between Concentrations of Glucose in Blood and Interstitial Fluid in Type 1 Diabetics Microdialysis, Guardian RT, Glucoday S - Type 1 Diabetes | Completed | Medical University of Graz | 16 | 2006-02-01 | 2007-07-12 | |
| Investigation of Correlation Between Interstitial and Arterial Blood Glucose Concentrations in Septic Patients microdialysis, microperfusion - Severe Sepsis | Completed | Medical University of Graz | 10 | 2005-09-01 | 2007-06-06 | |
| Influence of Treatment With Olanzapine or Ziprasidone on Transcapillary Glucose Transport in Human Skeletal Muscle ziprasidone or olanzapine, hyperinsulinaemic euglycaemic clamp, microdialysis (skeletal muscle) - Healthy Male Volunteers | Phase 4 | Completed | Medical University of Vienna | 2005-04-01 | 2006-10-18 |
Brain Neoplasms (3) · Glioma (3) · Glioblastoma (2) · Aortic Aneurysm (1) · Aortic Diseases (1) · Aortic Dissection (1) · Astrocytoma (1) · Brain Injuries, Traumatic (1) · Critical Illness (1) · Diabetes Mellitus, Type 1 (1) · Ependymoma (1) · Gliosarcoma (1) · Hypothermia (1) · Infertility, Female (1) · Mediastinitis (1)
City of Hope Medical Center (2) · Mayo Clinic (2) · Medical University of Graz (2) · Medical University of Vienna (2) · Assistance Publique - Hôpitaux de Paris (1) · Barts & The London NHS Trust (1) · Charite University, Berlin, Germany (1) · Chinese Medical Association (1) · Imperial College London (1) · Martin-Luther-Universität Halle-Wittenberg (1) · Military Hospital of Tunis (1) · Odense University Hospital (1) · Tejs Ehlers Klug (1) · University Hospital, Ghent (1) · University of Colorado, Denver (1)
Austria (5) · United States (5) · Denmark (2) · United Kingdom (2) · Belgium (1) · China (1) · France (1) · Germany (1) · Italy (1) · Slovenia (1) · Switzerland (1) · Tunisia (1)
Aung Ye Oo, MD, FRCS-CTh (1) · David Sharp (1) · Jana Portnow (1) · Jana Portnow, MD (1) · Margaux Pontailler, MD (1) · Markus Mueller, MD (1) · Michael Sander (1) · Nanette Santoro, MD (1) · Palle Toft, Professor (1) · Pieter De Cock, Prof. (1) · Siegfried Kasper, Prof. MD (1) · Tejs Ehlers Klug, MD, DMSc (1) · Terence C Burns, MD, PhD (1) · Terence C. Burns, MD, PhD (1)
PMID 23065438, PMID 23380277, PMID 31438849, PMID 31702640, PMID 38115038, PMID 39422741
R37CA276851 (2), 2008 (1), 2025 (1), R61NS122096 (1), U54HD058155 (1)