12 completed. 12 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 12 | Completed 12 |
| Phase 2 | 1 | Completed 1 |
Follow Lv: new trials by email Literature Review of Lv trials Research Report on Lv
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Andecaliximab With mFOLFOX6 as First Line Treatment for Advanced Gastric or Gastroesophageal Junction Adenocarcinoma Andecaliximab, Placebo, Leucovorin - Gastric Adenocarcinoma | Phase 3 | Completed | Gilead Sciences | 432 | 2015-10-13 | 2020-05-26 |
| Individual Dosage Selection of Irinotecan (CPT-11) Based on UGT1A1 Genotype in Metastatic Colorectal Cancer Patients Irinotecan Injection [Camptosar], 5-fluorouracil, Leucovorin - Metastatic Colorectal Cancer | Phase 2 / Phase 3 | Completed | The Affiliated Hospital of the Chinese Academy of Military Medical Sciences | 583 | 2012-03-08 | 2017-03-30 |
| Low-Dose or High-Dose Vincristine and Combination Chemotherapy in Treating Young Patients With Relapsed B-Cell Acute Lymphoblastic Leukemia vincristine sulfate, prednisone, doxorubicin hydrochloride - B-cell Childhood Acute Lymphoblastic Leukemia, L1 Childhood Acute Lymphoblastic Leukemia | Phase 3 | Completed | Children's Oncology Group | 275 | 2007-03-01 | 2024-03-26 |
| Randomized Phase III Study of Folfiri+Avastin Versus Xeliri+Avastin as 1st Line Treatment of CRC Irinotecan, 5-Fluorouracil, Leucovorin - Colorectal Cancer | Phase 3 | Completed | Hellenic Oncology Research Group | 330 | 2006-12-01 | 2010-08-19 |
| Evaluation of the Efficacy of Xaliproden (SR57746A) in Preventing the Neurotoxicity of Oxaliplatin / 5FU/LV Chemotherapy. Xaliproden (SR57746A), Placebo, Oxaliplatin - Metastases, Colorectal Neoplasms | Phase 3 | Completed | Sanofi | 879 | 2005-12-01 | 2016-05-04 |
| Comparison of Combination Chemotherapy Regimens With or Without Cetuximab in Treating Patients Who Have Undergone Surgery For Stage III Colon Cancer irinotecan hydrochloride, oxaliplatin, leucovorin calcium - Adenocarcinoma of the Colon, Stage III Colon Cancer | Phase 3 | Completed | National Cancer Institute (NCI) | 3397 | 2004-02-01 | 2026-06-23 |
| Comparison of Adjuvant Chemotherapy Regimens in Treating Stage II/III Rectal Cancer Radiotherapy, Fluorouracil, Leucovorin Calcium - Rectal Mucinous Adenocarcinoma, Rectal Signet Ring Cell Adenocarcinoma | Phase 3 | Completed | National Cancer Institute (NCI) | 225 | 2003-10-15 | 2018-12-04 |
| Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Children With Acute Lymphoblastic Leukemia filgrastim, asparaginase, cyclophosphamide - Childhood Acute Lymphoblastic Leukemia in Remission, Recurrent Childhood Acute Lymphoblastic Leukemia | Phase 3 | Completed | National Cancer Institute (NCI) | 220 | 2002-10-01 | 2014-02-27 |
| Combination Chemotherapy With or Without Bevacizumab Compared With Bevacizumab Alone in Treating Patients With Advanced or Metastatic Colorectal Cancer That Has Been Previously Treated bevacizumab, oxaliplatin, leucovorin calcium - Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum | Phase 3 | Completed | National Cancer Institute (NCI) | 880 | 2001-09-01 | 2013-01-24 |
| Fluorouracil Plus Leucovorin With or Without Oxaliplatin in Treating Patients With Stage II or Stage III Colon Cancer leucovorin calcium, fluorouracil, oxaliplatin - Stage II Colon Cancer, Stage III Colon Cancer | Phase 3 | Completed | National Cancer Institute (NCI) | 2472 | 2000-02-01 | 2013-01-14 |
| Irinotecan Compared With Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer irinotecan hydrochloride, oxaliplatin, leucovorin calcium - Mucinous Adenocarcinoma of the Colon, Mucinous Adenocarcinoma of the Rectum | Phase 3 | Completed | National Cancer Institute (NCI) | 560 | 1999-11-01 | 2013-05-03 |
| SWOG-9304 Chemotherapy Plus Radiation Therapy in Treating Patients With Rectal Cancer That Has Been Surgically Removed fluorouracil, leucovorin calcium, levamisole hydrochloride - Colorectal Cancer | Phase 3 | Completed | SWOG Cancer Research Network | 1917 | 1994-03-01 | 2013-04-05 |
Colonic Neoplasms (4) · Colorectal Neoplasms (4) · Rectal Neoplasms (4) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (2) · Diarrhea (1) · Neoplasm Metastasis (1) · Neurotoxicity Syndromes (1) · Neutropenia (1) · Paresthesia (1) · Stomach Neoplasms (1)
National Cancer Institute (NCI) (6) · Children's Oncology Group (1) · Gilead Sciences (1) · Hellenic Oncology Research Group (1) · SWOG Cancer Research Network (1) · Sanofi (1) · The Affiliated Hospital of the Chinese Academy of Military Medical Sciences (1)
United States (10) · Canada (4) · Australia (3) · Chile (2) · Germany (2) · Hungary (2) · Italy (2) · Poland (2) · Spain (2) · United Kingdom (2) · Argentina (1) · Belgium (1) · Brazil (1) · China (1) · Colombia (1)
Al B. Benson, MD, FACP (1) · Al Benson (1) · Anthony LA Fields, MD, FRCPC (1) · Bruce Giantonio (1) · Glen Lew, MD (1) · Henry Pitot (1) · Jaffer A. Ajani, MD (1) · Jian-Ming Xu, M.D. (1) · John Kuebler (1) · John Souglakos, MD (1) · Kirk Schultz (1) · Michael J. O'Connell, MD (1) · Robert J. Mayer, MD, FACP (1)
PMID 31268130, PMID 33356421, PMID 16877719, PMID 17470851, PMID 17853393, PMID 20233444, PMID 21859995, PMID 21997132, PMID 22240792, PMID 22474202, PMID 23623224, PMID 24220557, PMID 27270348, PMID 28006055, PMID 28983557, PMID 30679026, PMID 31378656, PMID 31811950, PMID 32001530, PMID 32085892, PMID 32165096, PMID 33203692, PMID 33242441, PMID 33863713, PMID 35963480, PMID 36306483, PMID 36606664, PMID 38315963, PMID 41397917
U10CA021115 (2), U10CA025224 (2), U10CA098543 (2), 2015 (1), U10CA012027 (1), U10CA032102 (1)