5 completed, 2 not yet recruiting, 1 enrolling by invitation, 1 terminated. 8 Not applicable, 1 Early Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 8 | Completed 4, Not yet recruiting 2, Enrolling by invitation 1, Terminated 1 |
| Early Phase 1 | 1 | Unknown 1 |
| Phase 2 | 1 | Completed 1 |
Follow this drug Literature Review of Luteolin trials Research Report on Luteolin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Palmitoylethanolamide/Luteolin Supplementation in Older Adults Undergoing Cardiac Surgery co-ultramicronized Palmitoylethanolamide + Luteolin (700 mg + 70 mg in 10 ml), Standard of Care - Postoperative Cognitive Dysfunction | Not applicable | Not yet recruiting | Fondazione IRCCS San Gerardo dei Tintori | 100 | 2026-06-01 | 2026-07-02 |
| The Role of Luteolin Supplementation in Cellular Metabolism of Myocytes and Fat Cells, Physical Performance, and Body Composition in Athletes. luteolin, Placebo - Healthy Athletes | Not applicable | Enrolling by invitation | University of Jordan | 50 | 2025-11-01 | 2025-12-12 |
| Palmitoylethanolamide and Luteolin in Patients with Acute Ischemic Stroke co-ultramicronized Palmitoylethanolamide + Luteolin (770 mg), Placebo, Thrombectomy - Acute Ischemic Stroke AIS | Not applicable | Not yet recruiting | Ospedali Riuniti Trieste | 60 | 2025-01-01 | 2025-01-16 |
| Influence of Luteolin for Two Weeks on Memory in Healthy Subjects Luteolin, Placebo - Memory | Not applicable | Completed | Prof. Dominique de Quervain, MD | 44 | 2023-11-28 | 2024-05-09 |
| Luteolin for the Treatment of People With Schizophrenia Luteolin, Placebo - Schizophrenia, Schizoaffective Disorder | Not applicable | Completed | University of Maryland, Baltimore | 85 | 2022-06-13 | 2026-04-22 |
| Influence of Luteolin on Memory in Healthy Subjects Luteolin, Placebo - Memory | Not applicable | Terminated | University of Basel | 40 | 2020-01-01 | 2020-07-13 |
| Therapeutic Effect Of Luteolin Natural Extract Versus Its Nanoparticles On Tongue Squamous Cell Carcinoma Cell Line luteolin, nano-luteolin - Tongue Neoplasms, Carcinoma | Early Phase 1 | Unknown | Cairo University | 4 | 2017-11-01 | 2017-09-20 |
| Effects of Natural Supplement Containing Chlorogenic Acid and Luteolin on Cardio-metabolic Risk Factors Natural supplement containing chlorogenic acid and luteolin, Placebo (without any active ingredients) - Metabolic Syndrome | Not applicable | Completed | University of Palermo | 100 | 2017-06-01 | 2018-10-24 |
| Effects of Botanical Microglia Modulators in Gulf War Illness Boswellia Serrata, Curcumin, Epimedium - Gulf War Illness | Not applicable | Completed | University of Alabama at Birmingham | 36 | 2016-07-01 | 2025-01-24 |
| Effects of the Anti-inflammatory Flavonoid Luteolin on Behavior in Children With Autism Spectrum Disorders Luteolin, Quercetin and Rutin combined in a capsule - Autism Spectrum Disorders | Phase 2 | Completed | Attikon Hospital | 50 | 2011-12-01 | 2013-05-07 |
Neuroinflammatory Diseases (2) · Autism Spectrum Disorder (1) · Carcinoma (1) · Cognitive Dysfunction (1) · Metabolic Syndrome (1) · Mouth Neoplasms (1) · Persian Gulf Syndrome (1) · Postoperative Cognitive Complications (1) · Psychotic Disorders (1) · Schizophrenia (1) · Stroke (1) · Tongue Neoplasms (1)
Attikon Hospital (1) · Cairo University (1) · Fondazione IRCCS San Gerardo dei Tintori (1) · Ospedali Riuniti Trieste (1) · Prof. Dominique de Quervain, MD (1) · University of Alabama at Birmingham (1) · University of Basel (1) · University of Jordan (1) · University of Maryland, Baltimore (1) · University of Palermo (1)
Italy (3) · Switzerland (2) · United States (2) · Greece (1) · Jordan (1)
Ahmed Elkhadem, PhD (1) · Christiane Gerhards, MD (1) · Deanna Kelly, PharmD (1) · Dominique de Quervain, MD (1) · Dominique de Quervain, Prof (1) · Giuseppe Bellelli (1) · Hadeel A Ghazzawi, professor (1) · Jarred W Younger, PhD (1) · Manfredi Rizzo, MD, PhD (1) · Marcello Naccarato, MD, PhD (1)
PMID 23688534, PMID 33802272, PMID 33802381, PMID 33915962
2019 (1), 2023 (1)