7 completed, 2 terminated, 1 withdrawn. 10 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 10 | Completed 7, Terminated 2, Withdrawn 1 |
| Phase 2 | 2 | Terminated 1, Withdrawn 1 |
Follow Lovastatin: new trials by email Literature Review of Lovastatin trials Research Report on Lovastatin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| DSAP Treatment Comparison: 2% Lovastatin/ 2% Cholesterol vs 2% Lovastatin Alone Lovastatin 2%, 2% Cholesterol Cream, Lovastatin 2% Cream - Actinic Porokeratosis | Phase 1 | Completed | Medical University of South Carolina | 31 | 2020-08-24 | 2023-12-07 |
| Compare Pharmacokinetic(PK) Profiles of XZK vs Lovastatin in Healthy Male Volunteers XueZhiKang, Lovastatin - Lipid Metabolism Disorder | Phase 1 | Completed | Luye Pharma Group Ltd. | 20 | 2015-11-01 | 2016-12-05 |
| Human Cytochrome P450 4F Enzymes and Drug Interactions Warfarin, Placebo, Lovastatin - Healthy Volunteers, Drug Drug Interactions | Phase 1 | Completed | University of North Carolina, Chapel Hill | 19 | 2010-12-01 | 2013-01-21 |
| Trial to Evaluate the Safety of Lovastatin in Individuals With Neurofibromatosis Type I (NF1) Lovastatin, placebo pill - Neurofibromatosis 1 | Phase 1 | Completed | University of California, Los Angeles | 44 | 2009-09-01 | 2016-11-22 |
| Neuroprotection With Statin Therapy for Acute Recovery Trial (Neu-START) lovastatin - Stroke | Phase 1 | Completed | Columbia University | 33 | 2005-09-01 | 2016-05-09 |
| Fasting Bioavailability Study of Lovastatin Tablets and Mevacor Tablets Lovastatin 40 mg tablets, Lovastatin (Mevacor®) 40 mg Tablets - Healthy | Phase 1 | Completed | Mutual Pharmaceutical Company, Inc. | 54 | 2004-09-01 | 2010-01-20 |
| Fed Bioavailability Study of Lovastatin Tablets and Mevacor Tablets Lovastatin 40 mg Tablets, Lovastatin (Mevacor®) 40 mg Tablets - Healthy | Phase 1 | Completed | Mutual Pharmaceutical Company, Inc. | 54 | 2004-07-01 | 2010-01-20 |
| A Study of the Proper Dosage of Lovastatin and Docetaxel for Patients With Cancer Lovastatin, Docetaxel - Any Cancer, Breast Cancer | Phase 1 | Terminated | Susan L Roeder | 9 | 2004-04-01 | 2018-10-19 |
| Dose Escalation Phase I/II Study of Lovastatin With High-Dose Cytarabine for Refractory or Relapsed AML Cytarabine, Lovastatin - Acute Myeloid Leukemia | Phase 1 / Phase 2 | Terminated | University of Iowa | 23 | 2001-06-01 | 2018-01-05 |
| Evaluation of Lovastatin in Severe Persistent Asthma Lovastatin, Placebo - Severe Persistent Asthma | Phase 1 / Phase 2 | Withdrawn | University of Chicago | 2013-06-21 |
Asthma (1) · Breast Neoplasms (1) · Ischemic Stroke (1) · Leukemia, Myeloid, Acute (1) · Lipid Metabolism Disorders (1) · Neurofibromatosis 1 (1) · Stroke (1)
Mutual Pharmaceutical Company, Inc. (2) · Columbia University (1) · Luye Pharma Group Ltd. (1) · Medical University of South Carolina (1) · Susan L Roeder (1) · University of California, Los Angeles (1) · University of Chicago (1) · University of Iowa (1) · University of North Carolina, Chapel Hill (1)
United States (7) · Canada (2)
Blanca Camoretti-Mercado, Ph.D. (1) · Carrie E Bearden, PhD (1) · Dirk Elston, MD (1) · Eric Sicard, MD (1) · Ji Chong, MD (1) · Kim LR Brouwer, PharmD PhD (1) · Michael Z Wang, PhD (1) · Mitchell Elkind, MD, MS (1) · Raymond Hohl, MD (1) · Simon LI, M.D. (1) · Susan Roman, DO (1)
R01GM089994 (1), UL1RR024999 (1)