5 completed, 4 recruiting, 2 terminated, 1 active not recruiting. 8 Not applicable, 2 Phase 1, 2 Phase 2, 1 Early Phase 1, 1 Phase 3.
Follow Laser interstitial thermal therapy: new trials by email Literature Review of Laser interstitial thermal therapy trials Research Report on Laser interstitial thermal therapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Surgery and Laser Interstitial Thermal Therapy for Bilateral Glioblastomas surgery (any volume) and / or pharmaceuticals treatment initiated or planned or only dynamic observation, in accordance with current clinical guidelines - Brain Tumours, GBM | Not applicable | Recruiting | King's College Hospital NHS Trust | 12 | 2026-04-27 | 2026-09-03 |
| Laser Interstitial Thermal Therapy (LITT) and Lomustine (CCNU) for Recurrent Glioblastoma Laser interstitial thermal therapy, Lomustine - Glioblastoma | Phase 1 | Recruiting | University of California, Davis | 25 | 2025-10-01 | 2026-09-28 |
| LITT Combined With Early Use of Temozolomide for Recurrent Glioblastomas Laser interstitial thermal therapy, Temozolomide - Recurrent Glioblastoma | Phase 1 / Phase 2 | Unknown | Beijing Tiantan Hospital | 10 | 2022-12-01 | 2022-12-23 |
| Ventral Capsulotomy for Intractable OCD Laser Interstitial Thermal Therapy - Obsessive-Compulsive Disorder | Phase 3 | Enrolling by invitation | Butler Hospital | 50 | 2022-06-21 | 2023-01-26 |
| REMASTer: REcurrent Brain Metastases After SRS Trial Radiation Therapy, Steroid Therapy, Laser Interstitial Thermal Therapy - Brain Metastases, Radiation Necrosis | Not applicable | Recruiting | Monteris Medical | 261 | 2022-05-10 | 2026-10-20 |
| Magnetic Resonance-Guided Laser Interstitial Thermal Therapy for Brain Metastases Trial Laser interstitial thermal therapy - Brain Metastasases | Not applicable | Completed | Beijing Tiantan Hospital | 98 | 2022-01-11 | 2025-08-20 |
| LITT Followed by Hypofractionated RT for Newly Diagnosed Gliomas (GCC 20138) LITT, Hypofractionated Radiation Therapy - Glioma, Glioblastoma | Not applicable | Recruiting | University of Maryland, Baltimore | 32 | 2021-02-20 | 2026-05-06 |
| LITT Followed by Hypofractionated RT for Recurrent Gliomas Procedure: LITT, Hypo-Fractionated Radiation Therapy - Glioblastoma, Brain Tumor | Not applicable | Active not recruiting | University of Maryland, Baltimore | 39 | 2020-01-08 | 2026-08-28 |
| Laser Interstitial Thermal Therapy and Lomustine in Treating Patients With Recurrent Glioblastoma or Anaplastic Astrocytoma Laser Interstitial Thermal Therapy, Lomustine - IDH Family Wildtype, Recurrent Anaplastic Astrocytoma | Phase 2 | Terminated | M.D. Anderson Cancer Center | 7 | 2017-11-07 | 2022-08-10 |
| Expedited Laser Interstitial Thermal Therapy + Chemoradiation For Newly Diagnosed High Grade Gliomas LITT, Radiation therapy, Temozolomide - High Grade Glioma | Early Phase 1 | Completed | Case Comprehensive Cancer Center | 13 | 2017-08-24 | 2026-08-06 |
| Stereotactic Laser Ablation for Temporal Lobe Epilepsy (Slate) Visualase MRI-Guided Laser Ablation - Temporal Lobe Epilepsy | Not applicable | Completed | MedtronicNeuro | 167 | 2016-12-01 | 2025-01-17 |
| Use of Laser Interstitial Thermal Therapy in the Focal Treatment of Localized Prostate Cancer Laser Interstitial Thermal Therapy - Prostate Cancer | Completed | Jonsson Comprehensive Cancer Center | 8 | 2014-09-11 | 2020-07-27 | |
| MR-Guided Laser Interstitial Thermal Therapy in Treating Patients With Prostate Cancer Visualase Thermal Therapy, magnetic resonance imaging - Stage I Prostate Cancer, Stage II Prostate Carcinoma | Not applicable | Completed | University of Chicago | 27 | 2013-01-28 | 2018-03-13 |
| Magnetic Resonance Thermal Image Guided Laser Interstitial Thermal Therapy in Treating Patients With Breast Cancer magnetic resonance thermal imaging, laser interstitial thermal therapy - Ductal Breast Carcinoma in Situ, Invasive Ductal Breast Carcinoma | Not applicable | Withdrawn | University of Chicago | 2012-08-01 | 2014-10-15 | |
| MRI-Guided Laser Induced Thermal Therapy laser interstitial thermal therapy - Malignant Glioma | Terminated | Rutgers, The State University of New Jersey | 1 | 2011-08-01 | 2014-05-22 |
Brain Neoplasms (5) · Glioblastoma (5) · Glioma (4) · Prostatic Neoplasms (2) · Astrocytoma (1) · Breast Neoplasms (1) · Carcinoma, Ductal, Breast (1) · Carcinoma, Intraductal, Noninfiltrating (1) · Epilepsy (1) · Epilepsy, Temporal Lobe (1) · Neoplasm Metastasis (1) · Neoplasms (1) · Obsessive-Compulsive Disorder (1) · Recurrence (1)
Beijing Tiantan Hospital (2) · University of Chicago (2) · University of Maryland, Baltimore (2) · Butler Hospital (1) · Case Comprehensive Cancer Center (1) · Jonsson Comprehensive Cancer Center (1) · King's College Hospital NHS Trust (1) · M.D. Anderson Cancer Center (1) · MedtronicNeuro (1) · Monteris Medical (1) · Rutgers, The State University of New Jersey (1) · University of California, Davis (1)
United States (12) · China (2) · United Kingdom (1)
Aytekin Oto (1) · Barbara J O'Brien (1) · Dabiao Zhou, MD (1) · Hiroyuki Abe (1) · Jennifer Yu, MD, PhD (1) · Michael Sperling, MD (1) · Orwa Aboud, MD, PhD (1) · Pantuck Alan, MD (1) · Peter Fecci, MD (1) · Robert Gross, MD, PhD (1) · Scott Eggener, MD (1) · Shabbar F Danish, MD (1) · Steven Raman, MD (1) · Wang Jia (1)
P30CA016672 (1), P30CA093373 (1), R21CA173751 (1)