6 completed, 3 unknown, 2 terminated, 1 withdrawn. 12 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 12 | Completed 6, Unknown 3, Terminated 2, Withdrawn 1 |
| Phase 2 | 2 | Unknown 2 |
Follow Laser: new trials by email Literature Review of Laser trials Research Report on Laser
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Randomized Trial of Low-Dose Bevacizumab vs Laser for Type 1 ROP Bevacizumab, Laser - Retinopathy of Prematurity | Phase 3 | Terminated | Jaeb Center for Health Research | 16 | 2022-04-27 | 2026-09-14 |
| Evaluation of Laser and Tranexamic Acid in Treatment of Melasma Tranexamic acid - Melasma | Phase 2 / Phase 3 | Unknown | Assiut University | 40 | 2020-12-01 | 2020-10-22 |
| Interest of Intravitreal Injections of Anti-VEGF as Initial and Adjuvant Treatment in Coats Disease Anti-VEGF injections of bevacizumab, Laser - Retinal Telangiectasis, Coats Disease | Phase 3 | Terminated | Fondation Ophtalmologique Adolphe de Rothschild | 18 | 2019-10-24 | 2025-12-10 |
| Laser Therapy Treatment of Peri-implantitis. Laser, Mechanical debridement - Peri-implantitis | Phase 3 | Withdrawn | University of Michigan | 2016-01-01 | 2015-04-03 | |
| A 12-month, Randomized, Efficacy and Safety Study of 0.5 mg Ranibizumab vs Laser in Chinese Diabetic Macular Edema (DME) Patients Ranibizumab (RFB002), Laser, Sham injection - Diabetic Macular Edema, Visual Impairment | Phase 3 | Completed | Novartis Pharmaceuticals | 384 | 2014-11-05 | 2019-02-01 |
| Safety and Efficacy Study of Conbercept in Diabetic Macular Edema (DME) (Sailing) Conbercept, Sham injection, Laser - Diabetic Macular Edema | Phase 3 | Unknown | Chengdu Kanghong Biotech Co., Ltd. | 248 | 2014-07-01 | 2016-01-06 |
| Efficacy and Safety of Ranibizumab With or Without Laser in Comparison to Laser in Branch Retinal Vein Occlusion Ranibizumab, Laser - Branch Retinal Vein Occlusion | Phase 3 | Completed | Novartis Pharmaceuticals | 455 | 2012-05-01 | 2016-11-10 |
| Photodynamic Therapy (PDT) for Palliation of Cholangiocarcinoma Photodynamic Therapy - Cholangiocarcinoma, Biliary Stricture | Phase 2 / Phase 3 | Unknown | Weill Medical College of Cornell University | 55 | 2012-02-01 | 2017-02-20 |
| Extended Follow-up of Patients With Macular Edema Due to Retinal Vein Occlusion ranibizumab, Peripheral Laser - Retinal Vein Occlusion | Phase 3 | Completed | Peter A Campochiaro, MD | 66 | 2010-08-01 | 2014-01-13 |
| Safety, Efficacy and Cost-efficacy of Ranibizumab (Monotherapy or Combination With Laser) in the Treatment of Diabetic Macular Edema (DME) ranibizumab, Laser - Diabetic Macular Edema | Phase 3 | Completed | Novartis Pharmaceuticals | 241 | 2010-07-01 | 2014-10-23 |
| A 12 Month Core Study to Assess the Efficacy and Safety of Ranibizumab (Intravitreal Injections) in Patients With Visual Impairment Due to Diabetic Macular Edema and a 24 Month Open-label Extension Study Ranibizumab, Laser, Sham laser - Diabetic Macular Edema | Phase 3 | Completed | Novartis | 345 | 2008-05-01 | 2013-04-01 |
| Clinical Trial of Cryotherapy Versus Postoperative Laser Photocoagulation criopexy, laser - Rhegmatogenous Retinal Detachment | Phase 3 | Completed | University of Campinas, Brazil | 86 | 2006-07-01 | 2010-05-26 |
Macular Edema (3) · Vision Disorders (3) · Diabetes Mellitus (2) · Retinal Vein Occlusion (2) · Bile Duct Neoplasms (1) · Cholangiocarcinoma (1) · Edema (1) · Melanosis (1) · Peri-Implantitis (1) · Retinal Diseases (1) · Retinal Telangiectasis (1) · Retinopathy of Prematurity (1)
Novartis Pharmaceuticals (3) · Assiut University (1) · Chengdu Kanghong Biotech Co., Ltd. (1) · Fondation Ophtalmologique Adolphe de Rothschild (1) · Jaeb Center for Health Research (1) · Novartis (1) · Peter A Campochiaro, MD (1) · University of Campinas, Brazil (1) · University of Michigan (1) · Weill Medical College of Cornell University (1)
Canada (4) · United States (4) · France (3) · Australia (2) · China (2) · Greece (2) · Hungary (2) · Italy (2) · Netherlands (2) · Spain (2) · Switzerland (2) · United Kingdom (2) · Belgium (1) · Czechia (1) · Denmark (1)
David K Wallace, MD, MPH (1) · Fernando Suarez, DDS (1) · Michel Kahaleh, MD (1) · Peter A Campochiaro, MD (1)
PMID 21149772, PMID 21459215, PMID 23974915, PMID 24491642, PMID 25148789, PMID 26327116, PMID 26584450, PMID 27039022, PMID 28807635, PMID 34001667, PMID 34934034
UG1EY011751 (1)