26 completed, 3 not yet recruiting, 2 recruiting, 2 withdrawn. 20 Not applicable, 1 Phase 1, 1 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 20 | Completed 15, Not yet recruiting 3, Recruiting 1, Suspended 1 |
| Phase 1 | 1 | Withdrawn 1 |
| Phase 2 | 1 | Completed 1 |
| Phase 4 | 1 | Completed 1 |
Follow Laparoscopic Appendectomy: new trials by email Literature Review of Laparoscopic Appendectomy trials Research Report on Laparoscopic Appendectomy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparative Study Between Laparoscopic and Open Appendectomy of Complicated Appendicitis Laparoscopic Appendectomy, Open Appendectomy - Appendicitis, Perforated Appendicitis | Not applicable | Not yet recruiting | Assiut University | 100 | 2026-11-01 | 2026-10-16 |
| Laparoscopic vs Open Appendectomy in Obese Patients Open Appendectomy, Laparoscopic Appendectomy - Acute Appendicitis, Appendicitis (Diagnosis) | Not applicable | Not yet recruiting | University of Health Sciences Lahore | 166 | 2026-10-02 | 2026-09-16 |
| Video-Based Grading of Intraoperative Adverse Events in Pediatric Laparoscopic Appendectomy Laparoscopic appendectomy - Appendicitis, Acute, Appendectomy | Recruiting | Ahmet Burak Doğan, MD | 80 | 2026-09-01 | 2026-09-04 | |
| Laparoscopic vs Open Appendectomy Laparoscopic appendectomy, Open Appendectomy - Acute Appendicitis, Superficial SSI | Not applicable | Completed | Quaid-e-Azam Medical College | 276 | 2026-01-24 | 2026-09-25 |
| Direct Visualization ERAT Versus Laparoscopic Appendectomy in Adults With Acute Uncomplicated Appendicitis Direct Visualization Endoscopic Retrograde Appendicitis Therapy, Laparoscopic appendectomy - Acute Uncomplicated Appendicitis | Not applicable | Recruiting | Changhai Hospital | 376 | 2025-12-10 | 2026-09-04 |
| Bowel Obstruction Post Open Versus Laparoscopic Appendectomy Open appendectomy, Laparoscopic appendectomy - Bowel Obstruction | Not applicable | Completed | Sohag University | 50 | 2025-07-01 | 2026-07-21 |
| Use of Bipolar Diathermy VS Clips in Laparoscopic Appendectomy laparoscopic appendectomy, bipolar diathermy, clips closure - Laparoscopic Appendectomy, Bipolar Diathermy | Not applicable | Not yet recruiting | Assiut University | 100 | 2025-03-01 | 2025-02-14 |
| Non-operative vs. Operative Management of Acute Appendicitis in Vulnerable Patient Populations Laparoscopic appendectomy, Antibiotics (IV transitioned to oral) - Acute Appendicitis | Phase 1 | Withdrawn | University of Texas Southwestern Medical Center | 2023-10-01 | 2024-03-26 | |
| Efficacy of LigaSure Versus Harmonic Scalpel US in Laparoscopic Appendectomy in Management of Acute Appendicitis laparoscopic appendectomy - Appendicitis Acute | Completed | Zagazig University | 60 | 2023-01-01 | 2025-07-29 | |
| Evaluation of One Day Discharge After Laparoscopic Appendectomy for Uncomplicated Appendicitis in Children. Laparoscopic Appendectomy - Appendicitis Acute | Not applicable | Completed | Miro Jukić | 180 | 2021-10-02 | 2022-07-20 |
| Low vs Medium Pressure Pneumoperitoneum Laparoscopic appendectomy - Appendicitis Acute | Not applicable | Completed | University Children's Hospital, Zurich | 250 | 2021-09-27 | 2026-07-30 |
| The Optimization of a Low-dose CT Protocol in Patients With Suspected Uncomplicated Acute Appendicitis and BMI >30 Low-dose CT, Laparoscopic appendectomy - Appendicitis, Other and Unspecified Acute Appendicitis | Not applicable | Suspended | Turku University Hospital | 30 | 2020-11-04 | 2022-02-25 |
| the Impact of COVID-19 Pandemic on the Incidence and Outcome of Complicated Appendicitis laparoscopic appendectomy - Covid19, Appendicitis | Completed | Meir Medical Center | 200 | 2020-03-01 | 2021-03-08 | |
| The Role of Preoperative HALP Score in Differentiating Complicated Acute Appendicitis Appendectomy, blood sampling - Acute Appendicitis, Acute Appendicitis Without Peritonitis | Completed | Kahramanmaras Sutcu Imam University | 411 | 2020-01-01 | 2025-06-26 | |
| Identification of the Optimal Treatment Strategy for Complex Appendicitis in the Pediatric Population Laparoscopic appendectomy, Open appendectomy, Non-operative treatment - Appendicitis, Appendix Mass | Completed | Ramon Gorter | 1308 | 2019-08-12 | 2024-07-30 | |
| Usage of Multiple Drugs in Treatment of Postoperative Vomiting After Laparoscopic Appendectomy Ondansetron, isopropyl alcohol 70% inhalation, laparoscopic appendectomy - to Treat the Vomiting Frequently Occur Post-laparoscopic by Different Anti Emetic Drugs | Completed | King Abdul Aziz Specialist Hospital | 240 | 2019-03-10 | 2020-05-28 | |
| Analysis of Endoloops, Endostaples and Endoclips for Closing the Appendiceal Stump During Laparoscopic Appendectomy Technique used for closing the appendiceal stump - Appendicitis Acute, Laparoscopic Surgery | Not applicable | Completed | University Hospital Dubrava | 300 | 2019-01-01 | 2020-03-30 |
| COlonic Salvage by Therapeutic Appendectomy. Laparoscopic appendectomy, Endoscopic appendix biopsies - Colitis, Ulcerative | Not applicable | Completed | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 123 | 2018-08-24 | 2024-10-02 |
| Grey Zone Appendicitis: Role of Blood Test Biomarkers to Detect Early Appendicitis and to Decrease the Incidence of Negative Appendectomy laparoscopic appendectomy - Appendicitis | Not applicable | Completed | Zagazig University | 2 | 2018-08-01 | 2020-02-17 |
| Acute Appendicitis in Foreign Workers of Northern Israel Laparoscopic appendectomy - Surgery | Completed | HaEmek Medical Center, Israel | 117 | 2018-01-01 | 2021-05-21 |
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Appendicitis (30) · Abdominal Abscess (2) · Acute Disease (2) · Gastrointestinal Diseases (2) · Intraabdominal Infections (2) · COVID-19 (1) · Colitis, Ulcerative (1) · Disease (1) · Intestinal Obstruction (1) · Intraoperative Complications (1) · Obesity (1) · Pain (1) · Peritonitis (1) · Pneumoperitoneum (1) · Surgical Wound Infection (1)
Assiut University (2) · Children's Mercy Hospital Kansas City (2) · Turku University Hospital (2) · Zagazig University (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Ahmet Burak Doğan, MD (1) · Changhai Hospital (1) · Far Eastern Memorial Hospital (1) · HaEmek Medical Center, Israel (1) · Hanoi Medical University (1) · Helsinki University Central Hospital (1) · Kahramanmaras Sutcu Imam University (1) · Karolinska University Hospital (1) · King Abdul Aziz Specialist Hospital (1) · Medical Park Gaziantep Hospital (1)
Egypt (4) · Finland (4) · Croatia (3) · United States (3) · Israel (2) · Netherlands (2) · Turkey (Türkiye) (2) · China (1) · Denmark (1) · Pakistan (1) · Russia (1) · Saudi Arabia (1) · Sweden (1) · Switzerland (1) · Taiwan (1)
Paulina Salminen, MD, PhD (2) · Alexander V Sazhin, Prof. (1) · Christianne Buskens, MD, PhD (1) · Claus A Bertelsen, Ph.D. (1) · David Bliss, M.D. (1) · Hannah R Neeser, MD (1) · Heng-Fu Lin, MD (1) · Jan F Svensson, MD (1) · Mehmet Kaplan, M.D. (1) · Panu Mentula, M.D. Ph.D. (1) · Ramon Gorter, MD PhD (1) · Ranko Stare, MD, PhD (1) · Shawn D St. Peter, MD (1)
PMID 20632312, PMID 21946218, PMID 22964730, PMID 25072441, PMID 26141467, PMID 27582784, PMID 29637088, PMID 31800496, PMID 32612104, PMID 33047586, PMID 34312724, PMID 35177453, PMID 39826968, PMID 41291390, PMID 41512889