8 completed, 2 terminated, 1 recruiting, 1 unknown. 6 Phase 3, 5 Phase 2, 2 Not applicable, 2 Phase 1, 1 Early Phase 1.
Follow Lactose monohydrate: new trials by email Literature Review of Lactose monohydrate trials Research Report on Lactose monohydrate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pancrelipase With Nutritional Supplement in Patients at Risk of Malnutrition (EFFORT-ENZO) Zenpep, Placebo - Malnutrition | Not applicable | Recruiting | Philipp Schuetz | 20 | 2025-09-22 | 2026-09-22 |
| Amantadine for COVID-19 Amantadine, Lactose monohydrate - Covid19 | Phase 3 | Unknown | Copenhagen University Hospital, Hvidovre | 226 | 2021-06-01 | 2021-10-06 |
| Value of Inhaled Treatment With Aztreonam Lysine in Bronchiectasis Aztreonam lysine, Placebo - Bronchiectasis Adult | Phase 4 | Terminated | University of Dundee | 34 | 2019-10-19 | 2026-01-12 |
| Effect of Addition of Aromatase Inhibitor to Ovarian Stimulation Therapy in IVF Treatment Letrozole, Placebo - Infertility | Phase 2 / Phase 3 | Completed | Sven O. Skouby | 129 | 2017-02-01 | 2019-07-08 |
| Mapping the Endocrine Determinants of Ovarian Stimulation to Optimize Outcomes in Fresh Embryo Transfer Cycles Placebo, Letrozole - Infertility | Phase 2 / Phase 3 | Completed | Sven O. Skouby | 33 | 2016-08-01 | 2019-02-05 |
| Biomarkers of Neuroinflammation and Anti-Inflammatory Treatments in Major Depressive Disorder Minocycline, Placebo, Celecoxib - Major Depressive Disorder | Early Phase 1 | Completed | Centre for Addiction and Mental Health | 115 | 2015-02-01 | 2019-05-23 |
| Prucalopride Versus Placebo in Gastroparesis Prucalopride, Placebo - Gastroparesis, Diabetes Mellitus | Phase 2 / Phase 3 | Completed | University of Calgary | 15 | 2014-03-01 | 2020-10-08 |
| Fenobam on Heat/Capsaicin Induced Hyperalgesia in Healthy Volunteers Fenobam, Placebo - Hyperalgesia, Allodynia | Phase 1 | Completed | Laura Cavallone | 33 | 2014-01-01 | 2016-04-29 |
| Losmapimod in Chronic Obstructive Pulmonary Disease Patients Stratified by Fibrinogen. Losmapimod, Placebo - Chronic Obstructive Pulmonary Disease | Phase 2 | Completed | Cambridge University Hospitals NHS Foundation Trust | 72 | 2012-06-01 | 2015-03-17 |
| Intracranial Pressure in Experimental Models of Headache Acetazolamide, Lactose monohydrate - High Altitude Headache | Not applicable | Completed | Bangor University | 23 | 2011-07-01 | 2012-02-07 |
| Rhodiola Rosea Therapy of Major Depressive Disorder Herbal extract, Sertraline, Lactose monohydrate - Depression | Phase 3 | Completed | University of Pennsylvania | 58 | 2010-06-01 | 2018-02-22 |
| Randomized Placebo-controlled Trial Evaluating the Safety and Efficacy of Silymarin Treatment in Patients With Acute Viral Hepatitis Silymarin, Lactose monohydrate - Acute Hepatitis A, Acute Hepatitis B | Phase 2 / Phase 3 | Terminated | University of Maryland, Baltimore | 70 | 2008-10-01 | 2021-04-23 |
| Effects of Tranilast on Pharmacokinetics of Methotrexate (MTX) in Patients With Rheumatoid Arthritis (RA) Tranilast, Placebo comparator - Rheumatoid Arthritis | Phase 1 | Withdrawn | Imperial College London | 2008-09-01 | 2015-05-28 |
Infertility (2) · Arthritis, Rheumatoid (1) · Atherosclerosis (1) · Bronchiectasis (1) · COVID-19 (1) · Depression (1) · Depressive Disorder, Major (1) · Diabetes Mellitus (1) · Gastroparesis (1) · Hepatitis (1) · Hyperalgesia (1) · Hypoxia (1) · Malnutrition (1) · Pulmonary Disease, Chronic Obstructive (1)
Sven O. Skouby (2) · Bangor University (1) · Cambridge University Hospitals NHS Foundation Trust (1) · Centre for Addiction and Mental Health (1) · Copenhagen University Hospital, Hvidovre (1) · Imperial College London (1) · Laura Cavallone (1) · Philipp Schuetz (1) · University of Calgary (1) · University of Dundee (1) · University of Maryland, Baltimore (1) · University of Pennsylvania (1)
Denmark (3) · United Kingdom (3) · Canada (2) · United States (2) · Egypt (1) · Switzerland (1)
Sven O. Skouby, Professor (2) · Christopher N Andrews, MD, MSc (1) · George T Strickland, MD, PhD, (1) · James Chalmers, MBChB, MRCP (1) · Jeffrey H Meyer, MD, PhD (1) · Joseph Cheriyan, MD (1) · Jun J. Mao, MD (1) · Justin S Lawley, BSc (1) · Laura F Cavallone, M.D. (1) · Michael Polkey, MD (1) · Mohamed Hashem, MD (1) · Nina M Weis, PhD (1) · Peter C Taylor, PhD (1) · Philipp Schuetz, Prof. MD (1) · Samer El-Kamary, MD, MPH (1)
PMID 34792133, PMID 37699851, PMID 22994519, PMID 25837277, PMID 35356508, PMID 35652260
2015 (2), 2018 (1), R21AT005230 (1)