5 completed, 1 recruiting, 1 withdrawn. 5 Phase 1, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Completed 4, Withdrawn 1 |
| Phase 2 | 5 | Completed 4, Recruiting 1 |
Follow KRN 7000: new trials by email Literature Review of KRN 7000 trials Research Report on KRN 7000
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| BPC2001 for the Prevention of Acute Graft-Versus-Host Disease Following Haploidentical Stem Cell Transplantation BPC-2001 - Graft -Versus-host-disease, aGVHD | Phase 2 | Recruiting | BioPhoenix Co., Ltd. | 50 | 2025-10-29 | 2026-08-17 |
| RGI-2001 for the Prevention of Acute Graft-vs-Host Disease in Subjects Following Allogeneic Hematopoietic Stem Cell Transplantation RGI-2001, Standard of Care - Graft Vs Host Disease, Graft-versus-host-disease | Phase 2 | Completed | Regimmune Corporation | 49 | 2019-11-25 | 2024-05-28 |
| Intravenous Administration of RGI-2001 in Patient Undergoing Allogenic Hematopoietic Stem Cell Transplantation (AHSCT) RGI-2001, Calcineurin Inhibitors, Allogeneic Hematopoietic Stem Cell Transplantation - Graft Versus Host Disease | Phase 1 / Phase 2 | Completed | Regimmune Corporation | 68 | 2011-09-01 | 2019-10-23 |
| Combination of Lenalidomide and Autologous Mature Dendritic Cells Pulsed With KRN7000 in Myeloma Lenalidomide, Monocyte derived DCs loaded with KRN7000 - Myeloma | Phase 1 | Completed | Yale University | 6 | 2009-04-01 | 2016-06-21 |
| Phase I/II Trial of KRN7000 in Patients With Chronic Hepatitis C Infection KRN7000 - Chronic Hepatitis C | Phase 1 / Phase 2 | Completed | Foundation for Liver Research | 36 | 2003-08-01 | 2006-07-14 |
| KRN7000 in Chronic Hepatitis B KRN7000 - Hepatitis B, Chronic | Phase 1 / Phase 2 | Completed | Foundation for Liver Research | 28 | 2003-03-01 | 2006-08-15 |
| KRN7000 in Treating Patients With Solid Tumors KRN7000 - Lung Cancer, Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | Withdrawn | European Organisation for Research and Treatment of Cancer - EORTC | 1998-09-01 | 2012-07-11 |
Graft vs Host Disease (3) · Bronchiolitis Obliterans Syndrome (1) · Carcinoma, Non-Small-Cell Lung (1) · Hematologic Neoplasms (1) · Hepatitis B (1) · Hepatitis B, Chronic (1) · Hepatitis C, Chronic (1) · Leukemia (1) · Lung Neoplasms (1) · Myelodysplastic Syndromes (1) · Neoplasms, Plasma Cell (1)
Foundation for Liver Research (2) · Regimmune Corporation (2) · BioPhoenix Co., Ltd. (1) · European Organisation for Research and Treatment of Cancer - EORTC (1) · Yale University (1)
Netherlands (3) · United States (3) · Austria (1) · Belgium (1) · China (1) · Denmark (1) · France (1) · Germany (1) · Norway (1) · Switzerland (1) · United Kingdom (1)
Carin MJ van Nieuwkerk, MD, PhD (1) · Giuseppe Giaccone, MD, PhD (1) · Madhav Dhodapkar, MD (1) · Xiaodong Mo, PhD (1) · Yi-Bin Chen, MD (1)