6 recruiting, 1 active not recruiting. 7 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 7 | Recruiting 6, Active not recruiting 1 |
| Phase 2 | 2 | Recruiting 2 |
Follow Iza-bren: new trials by email Literature Review of Iza-bren trials Research Report on Iza-bren
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase 1 Study Of Izalontamab Brengitecan + Adagrasib In NSCLC - The IZA-A Trial Adagrasib, Iza-bren - Non-small Cell Lung Cancer | Phase 1 | Recruiting | M.D. Anderson Cancer Center | 18 | 2026-05-15 | 2026-08-11 |
| A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors BMS-986507, Osimertinib, Pembrolizumab - Lung Cancer, Breast Cancer | Phase 1 / Phase 2 | Recruiting | Bristol-Myers Squibb | 416 | 2025-02-04 | 2026-09-23 |
| A Study of BL-B01D1 in Patients With Multiple Solid Tumors, Including Recurrent or Metastatic Gynecological Malignancies BL-B01D1 - Gynecological Malignant Tumor, Solid Tumor | Phase 1 / Phase 2 | Recruiting | Sichuan Baili Pharmaceutical Co., Ltd. | 38 | 2023-06-25 | 2025-09-26 |
| A Study of BL-B01D1 in Patients With Unresectable Locally Advanced or Metastatic Breast Cancer and Other Solid Tumors BL-B01D1 - Breast Cancer, Solid Tumor | Phase 1 | Recruiting | Sichuan Baili Pharmaceutical Co., Ltd. | 36 | 2022-08-11 | 2026-08-27 |
| A Study of BL-B01D1 in Patients With Locally Advanced or Metastatic Urological Tumors and Other Solid Tumors BL-B01D1 - Locally Advanced or Metastatic Urinary Tumors, Other Solid Tumors | Phase 1 | Active not recruiting | Sichuan Baili Pharmaceutical Co., Ltd. | 4 | 2022-02-15 | 2025-09-26 |
| A Study of BL-B01D1 in Patients With Locally Advanced or Metastatic Gastrointestinal Tumor and Other Solid Tumor BL-B01D1 - Gastrointestinal Tumor | Phase 1 | Recruiting | Sichuan Baili Pharmaceutical Co., Ltd. | 96 | 2022-02-14 | 2026-08-27 |
| A Study of BL-B01D1 in Patients With Locally Advanced or Metastatic Solid Tumor BL-B01D1 - Locally Advanced or Metastatic Solid Tumor | Phase 1 | Recruiting | Sichuan Baili Pharmaceutical Co., Ltd. | 570 | 2021-11-29 | 2026-08-27 |
Carcinoma, Non-Small-Cell Lung (3) · Breast Neoplasms (2) · Carcinoma, Renal Cell (1) · Colorectal Neoplasms (1) · Digestive System Neoplasms (1) · Endometrial Neoplasms (1) · Esophageal Neoplasms (1) · Head and Neck Neoplasms (1) · Lung Neoplasms (1) · Neoplasm Metastasis (1) · Ovarian Neoplasms (1) · Pancreatic Neoplasms (1) · Small Cell Lung Carcinoma (1) · Stomach Neoplasms (1) · Triple Negative Breast Neoplasms (1)
Sichuan Baili Pharmaceutical Co., Ltd. (5) · Bristol-Myers Squibb (1) · M.D. Anderson Cancer Center (1)
China (5) · United States (2) · Australia (1) · Canada (1) · Chile (1) · France (1) · Italy (1) · Netherlands (1) · Spain (1) · Taiwan (1) · United Kingdom (1)
Jian Zhang (1) · Jian Zhang, PHD (1) · Jiong Wu (1) · Jun Guo, PHD (1) · Li Zhang, PHD (1) · Lin Shen, PHD (1) · Marcelo V Negrao, MD (1) · Xiaohua Wu, PHD (1)