9 completed, 2 unknown, 1 active not recruiting, 1 enrolling by invitation. 7 Not applicable, 2 Phase 2, 2 Phase 3, 2 Phase 4, 1 Early Phase 1.
Follow Intravenous morphine: new trials by email Literature Review of Intravenous morphine trials Research Report on Intravenous morphine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Rhomboid Intercostal Sub-serratus Plane Block Versus External Oblique Intercostal Block in Open Nephrectomy Rhomboid intercostal subserratus plane block, External oblique intercostal block, Intravenous morphine - Rhomboid Intercostal Sub-serratus Plane Block, External Oblique Intercostal Block | Not applicable | Recruiting | Cairo University | 90 | 2026-05-02 | 2026-06-11 |
| Intrathecal Analgesia in Laparoscopic Nissen Fundoplication. Fentanyl Intrathecal 20ug, NOL-guided intravenous morphine analgesia, Intrathecal Morphine 100ug - Perioperative Pain Management, Gastreoesophageal Reflux Disease | Not applicable | Enrolling by invitation | Karlstad Central Hospital | 63 | 2026-03-10 | 2026-06-05 |
| Sterile Water Injection vs Morphine for Renal Colic Single Intradermal Sterile Water Injection, Multiple Intradermal Sterile Water Injections, Intravenous Morphine - Renal Colic, Urolithiasis | Not applicable | Active not recruiting | University Tunis El Manar | 150 | 2026-01-20 | 2026-01-30 |
| Pain Control and Quality of Recovery After Intravenous Methadone Versus Intrathecal Morphine in Major Abdominal Surgery Methadone, Morphine - Pain, Postoperative | Early Phase 1 | Unknown | University of Virginia | 40 | 2024-08-06 | 2025-08-11 |
| Dexmedetomidine vs Dexamethasone as Adjuvant to Bupivacaine in Bilevel Erector Spinae Plane Block in Breast Surgeries Bilevel Erector spinae plane block, Bilateral Erector spinae plane block with dexamethasone, Bilateral Erector spinae plane block with dexmedetomidine - Analgesia | Not applicable | Completed | National Cancer Institute, Egypt | 68 | 2022-10-27 | 2024-10-29 |
| Comparison of Hemodynamic Changes With Morphine Versus Esmolol During Induction of Anaesthesia Intravenous morphine - Intubation Complication | Phase 1 / Phase 2 | Completed | Pakistan Navy Station Shifa Hospital | 110 | 2022-08-28 | 2023-10-04 |
| Erector Spinae Plane Block Versus General Anesthesia in Breast Cancer Surgeries Bilevel erector spinae plane block, Single level erector spinae plane block, Intravenous morphine - Analgesia | Not applicable | Completed | National Cancer Institute, Egypt | 126 | 2022-06-27 | 2024-01-23 |
| Comparison of Intrathecal and Intravenous Analgesia in Patients Undergoing Liver Resection Intravenous morphine, Intrathecal morphine - Liver Diseases, Liver Cancer | Not applicable | Unknown | Medical University of Warsaw | 36 | 2018-08-17 | 2018-10-04 |
| Transversus Abdominus Plane Block in Living Donor Hepatectomy surgically inserted Transversus abdominus plane catheter, Intravenous morphine, Bupevecaine - Living Donor Hepatectomy | Not applicable | Completed | AlRefaey Kandeel | 90 | 2016-03-01 | 2016-08-30 |
| Intravenous Lidocaine Versus Morphine for Severe Pain in the ED Intravenous lidocaine, Intravenous morphine - Pain | Phase 4 | Completed | Alameda Health System | 32 | 2016-03-01 | 2020-04-06 |
| CAUDAL BUPIVACAINE VERSUS INTRAVENOUS MORPHINE ON TIME TO FIRST ANALGESIC REQUIREMENT caudal bupivacaine, intravenous morphine - Post Operative Pain | Phase 4 | Completed | Makerere University | 70 | 2015-07-01 | 2016-04-11 |
| Efficacy of Intranasal Fentanyl at Reducing Pain During Abscess Incision and Drainage (I&D) in Children Intranasal Fentanyl, Intravenous Morphine - Abscess, Pain | Phase 3 | Completed | Columbia University | 20 | 2012-01-01 | 2019-04-30 |
| Efficacy Study of Nebulized Morphine and Intravenous Morphine in Post Traumatic Pain nebulized morphine, Intravenous morphine - Post Traumatic Pain | Phase 3 | Completed | University of Monastir | 200 | 2010-06-01 | 2014-07-23 |
| Efficacy and Safety of Intranasal Morphine for Pain After Third Molar Extraction Intranasal Placebo, Intranasal Morphine 15 mg, Immediate Release Oral Morphine 60 mg - Post-Operative Pain, Third Molar Extraction | Phase 2 | Completed | Javelin Pharmaceuticals | 225 | 2001-09-01 | 2008-01-04 |
Agnosia (4) · Pain (4) · Pain, Postoperative (3) · Abscess (1) · Emergencies (1) · Liver Diseases (1) · Liver Neoplasms (1) · Renal Colic (1) · Urinary Calculi (1) · Urolithiasis (1)
National Cancer Institute, Egypt (2) · AlRefaey Kandeel (1) · Alameda Health System (1) · Cairo University (1) · Columbia University (1) · Javelin Pharmaceuticals (1) · Karlstad Central Hospital (1) · Makerere University (1) · Medical University of Warsaw (1) · Pakistan Navy Station Shifa Hospital (1) · University Tunis El Manar (1) · University of Monastir (1) · University of Virginia (1)
Egypt (4) · United States (3) · Tunisia (2) · Pakistan (1) · Poland (1) · Sweden (1) · Uganda (1)
Walaa Y Elsabeeny, MD (2) · Andrew Herring, MD (1) · Daniel Fenster, MD (1) · Daniel Tsze, MD, MPH (1) · Kyle Christensen, DDS (1) · Peter Dayan, MD, MSc (1)
PMID 27387971, PMID 32112166, PMID 32444296, PMID 32571630, PMID 37823931, PMID 40956348
2025 (1)