159 completed, 37 terminated, 27 unknown, 8 withdrawn. 88 Phase 2, 54 Phase 1, 21 Not applicable, 6 Phase 3, 4 Early Phase 1.
Follow Immunohistochemistry Staining Method: new trials by email Literature Review of Immunohistochemistry Staining Method trials Research Report on Immunohistochemistry Staining Method
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| PRAME Immunohistochemistry-Guided Slow Mohs Micrographic Surgery for the Treatment of Stage 0 to IIc Cutaneous Melanoma Immunohistochemistry Staining Method, Mohs Surgery - Clinical Stage 0 Cutaneous Melanoma AJCC v8, Clinical Stage I Cutaneous Melanoma AJCC v8 | Not applicable | Suspended | University of California, Davis | 36 | 2025-10-24 | 2026-05-01 |
| Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial) Biopsy Procedure, Biospecimen Collection, Computed Tomography - Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm | Phase 2 | Recruiting | National Cancer Institute (NCI) | 500 | 2025-03-18 | 2026-10-20 |
| Predictive Biomarkers for IGF1R Targeted Therapy in Ovarian Cancer: a Retrospective Study Immunohistochemistry staining method - Ovarian Cancer | Unknown | Hillel Yaffe Medical Center | 40 | 2016-04-01 | 2016-03-25 | |
| AR-inhibitor Bicalutamide in Treating Patients With TNBC Bicalutamide, Physician's Choice - Breast Neoplasms | Phase 2 | Unknown | Jinling Hospital, China | 60 | 2015-01-01 | 2015-02-03 |
| Tissue and Blood Biomarkers From Patients With Stage III or Stage IV Melanoma Treated With Ipilimumab With or Without Sargramostim RNA analysis, in situ hybridization, polymerase chain reaction - Melanoma (Skin) | Completed | Eastern Cooperative Oncology Group | 270 | 2013-04-26 | 2017-05-17 | |
| Immunotherapy for Recurrent Ependymomas in Children Using Tumor Antigen Peptides With Imiquimod HLA-A2 restricted synthetic tumor antigen, Imiquimod, enzyme-linked immunosorbent assay - Ependymoma | Phase 1 | Terminated | James Felker | 23 | 2012-08-01 | 2026-02-05 |
| Studying Gene Expression and Location in Samples From Patients With Brain Tumors gene expression analysis, genetic linkage analysis, microarray analysis - Brain and Central Nervous System Tumors | Completed | Children's Oncology Group | 10 | 2012-04-01 | 2016-05-18 | |
| FOLFIRINOX Plus PF-04136309 in Patients With Borderline Resectable and Locally Advanced Pancreatic Adenocarcinoma Oxaliplatin, Irinotecan, Leucovorin - Pancreatic Neoplasms | Phase 1 | Completed | Washington University School of Medicine | 44 | 2012-04-01 | 2016-09-19 |
| Studying Gene Expression in Samples From Patients With Rhabdoid Tumors DNA analysis, gene expression analysis, mutation analysis - Brain and Central Nervous System Tumors, Kidney Cancer | Completed | Children's Oncology Group | 25 | 2012-03-01 | 2016-07-14 | |
| Vaccine Therapy Following Therapeutic Autologous Lymphocytes and Cyclophosphamide in Treating Patients With Metastatic Melanoma cyclophosphamide, aldesleukin, autologous tumor cell vaccine - Recurrent Melanoma, Stage IV Melanoma | Phase 1 | Completed | Fred Hutchinson Cancer Center | 12 | 2012-03-01 | 2014-04-21 |
| Studying Gene Expression in Samples From Younger Patients With Neuroblastoma gene expression analysis, protein expression analysis, enzyme-linked immunosorbent assay - Neoplastic Syndrome, Neuroblastoma | Completed | Children's Oncology Group | 75 | 2012-03-01 | 2016-05-18 | |
| Everolimus and Combination Chemotherapy in Treating Patients With Metastatic Stomach or Esophageal Cancer fluorouracil, leucovorin calcium, oxaliplatin - Adenocarcinoma of the Esophagus, Adenocarcinoma of the Gastroesophageal Junction | Phase 1 / Phase 2 | Completed | City of Hope Medical Center | 6 | 2012-02-01 | 2017-05-31 |
| Studying Biomarkers in Samples From Younger Patients With Wilms Tumor gene expression analysis, proteomic profiling, reverse transcriptase-polymerase chain reaction - Kidney Cancer | Completed | Children's Oncology Group | 20 | 2012-02-01 | 2016-05-18 | |
| Vandetanib in Preventing Head and Neck Cancer in Patients With Precancerous Head and Neck Lesions vandetanib, placebo, immunohistochemistry staining method - Lip and Oral Cavity Squamous Cell Carcinoma, Oral Cavity Verrucous Carcinoma | Phase 2 | Completed | University of Chicago | 20 | 2012-01-01 | 2021-01-14 |
| Biomarkers in Tissue Samples From Patients With Recurrent or Metastatic Head and Neck Cancer Treated on ECOG-E1395 and ECOG-E3301 gene expression analysis, in situ hybridization, immunohistochemistry staining method - Head and Neck Cancer | Completed | Eastern Cooperative Oncology Group | 155 | 2011-12-22 | 2017-05-17 | |
| Biomarkers in Blood and Tissue Samples From Patients With Epstein-Barr Virus-Positive Hodgkin Lymphoma DNA analysis, RNA analysis, cytogenetic analysis - Lymphoma, Nonneoplastic Condition | Completed | Children's Oncology Group | 50 | 2011-12-01 | 2016-05-17 | |
| Biomarkers in Tumor Samples From Younger Patients With Neuroblastoma fluorescence in situ hybridization, gene expression analysis, microarray analysis - Neuroblastoma | Completed | Children's Oncology Group | 5 | 2011-12-01 | 2016-07-11 | |
| Biomarkers in Patients With Metastatic or Recurrent Head and Neck Cancer Treated With Cisplatin and Cetuximab on ECOG-E5397 cetuximab, cisplatin, gene expression analysis - Head and Neck Cancer | Completed | Eastern Cooperative Oncology Group | 42 | 2011-11-11 | 2017-05-17 | |
| Brentuximab Vedotin and Combination Chemotherapy in Treating Older Patients With Previously Untreated Stage II-IV Hodgkin Lymphoma brentuximab vedotin, doxorubicin hydrochloride, vinblastine - Adult Lymphocyte Depletion Hodgkin Lymphoma, Adult Lymphocyte Predominant Hodgkin Lymphoma | Phase 2 | Completed | Northwestern University | 49 | 2011-11-01 | 2026-05-22 |
| Cancer Stem Cell Biomarkers as a Predictor of Response to Trastuzumab in Samples From Patients With Breast Cancer Previously Treated in the NSABP-B-31 Trial fluorescence in situ hybridization, immunohistochemistry staining method, immunologic technique - Breast Cancer | Unknown | NSABP Foundation Inc | 1874 | 2011-11-01 | 2015-05-08 |
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Breast Neoplasms (57) · Head and Neck Neoplasms (21) · Carcinoma, Non-Small-Cell Lung (19) · Squamous Cell Carcinoma of Head and Neck (19) · Lung Neoplasms (18) · Colorectal Neoplasms (17) · Colonic Neoplasms (15) · Melanoma (15) · Rectal Neoplasms (14) · Lymphoma (12) · Carcinoma, Renal Cell (11) · Lymphoma, Follicular (11) · Carcinoma, Ovarian Epithelial (10) · Ovarian Neoplasms (10) · Pancreatic Neoplasms (10)
City of Hope Medical Center (19) · Children's Oncology Group (13) · Case Comprehensive Cancer Center (11) · Alliance for Clinical Trials in Oncology (10) · ECOG-ACRIN Cancer Research Group (9) · Memorial Sloan Kettering Cancer Center (9) · Abramson Cancer Center at Penn Medicine (8) · National Cancer Institute (NCI) (8) · Vanderbilt-Ingram Cancer Center (8) · Eastern Cooperative Oncology Group (7) · Mayo Clinic (7) · NCIC Clinical Trials Group (6) · Roswell Park Cancer Institute (6) · SWOG Cancer Research Network (5) · University of California, San Francisco (5)
United States (149) · United Kingdom (17) · Canada (10) · Belgium (3) · Ireland (3) · Switzerland (3) · France (2) · Australia (1) · Austria (1) · Cyprus (1) · Israel (1) · Italy (1) · Netherlands (1) · Poland (1) · Portugal (1)
Angela Davies, MD (2) · Barbara Murphy, MD (2) · Bryan P. Schneider, MD (2) · Cassian Yee (2) · Daniel F. Hayes, MD (2) · F. Stephen Hodi, MD (2) · Gerald Gui, MD, MS, FRCS(Edin), FRCS(Eng) (2) · Jana Portnow (2) · Jill Kolesar, PharmD (2) · Julia Newton Bishop, MD (2) · Laura Goff, MD (2) · Maryann Fitzmaurice, MD (2) · Renuka Iyer, MD (2) · Sylvia Lee (2) · Vincent Chung, MD (2)
PMID 11882819, PMID 12121233, PMID 14520092, PMID 14654545, PMID 15829324, PMID 16164916, PMID 16192820, PMID 16514477, PMID 17330838, PMID 17551310, PMID 18024211, PMID 18090584, PMID 19875761, PMID 20035238, PMID 20063546, PMID 20142602, PMID 20309640, PMID 20667781, PMID 21092279, PMID 21285985, PMID 21321091, PMID 21458303, PMID 21494121, PMID 21570352, PMID 21584903, PMID 21677464, PMID 21791687, PMID 21816436, PMID 21865946, PMID 21990404, PMID 22044694, PMID 22127070, PMID 22160854, PMID 22595848, PMID 22868365, PMID 22915661, PMID 22989664, PMID 23096768, PMID 23169503, PMID 23303141, PMID 23380277, PMID 23456389, PMID 24618153, PMID 24799460, PMID 24831979, PMID 25173583, PMID 26123189, PMID 26187751, PMID 26276750, PMID 26774555
P30CA033572 (11), P30CA043703 (5), P30CA015083 (4), P30CA036727 (4), U10CA032102 (4), K12CA076930 (3), P30CA008748 (3), P30CA022453 (3), P30CA068485 (3), P30CA072720 (3), P30CA093373 (3), U10CA031946 (3), P30CA006973 (2), P30CA069533 (2), U10CA021115 (2)