immunoenzyme technique: Clinical Trials

88 trials of immunoenzyme technique, newest first

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57 completed, 15 terminated, 9 unknown, 7 withdrawn. 31 Phase 1, 28 Phase 2, 9 Not applicable, 2 Early Phase 1, 1 Phase 3.

By phase and status

PhaseTrialsStatus
Phase 131Completed 20, Withdrawn 6, Terminated 4, Unknown 1
Phase 228Completed 15, Terminated 8, Unknown 4, Withdrawn 1
Not applicable9Completed 4, Unknown 4, Withdrawn 1
Early Phase 12Completed 2
Phase 31Unknown 1

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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Edible Hepatitis B Vaccine Therapy in Healthy Participants Who Have Undergone Previous Vaccination
hepatitis B antigen peptide, placebo, immunoenzyme technique - Healthy, no Evidence of Disease
Not applicableWithdrawnRoswell Park Cancer Institute2013-02-012022-10-03
Ex Vivo-Expanded HER2-Specific T Cells and Cyclophosphamide After Vaccine Therapy in Treating Patients With HER2-Positive Stage IV Breast Cancer
HER-2/neu peptide vaccine, cyclophosphamide, ex vivo-expanded HER2-specific T cells - HER2-positive Breast Cancer, Male Breast Cancer
Phase 1WithdrawnUniversity of Washington2012-06-012013-05-17
Biomarkers in Samples From Patients With Chronic Lymphocytic Leukemia Treated on Clinical Trial ECOG-2997
cytogenetic analysis, flow cytometry, fluorescence activated cell sorting - Leukemia
CompletedECOG-ACRIN Cancer Research Group2252012-04-172017-05-17
Vaccine Therapy in Treating Patients With Colorectal, Stomach, or Pancreatic Cancer
laboratory biomarker analysis, enzyme-linked immunosorbent assay, flow cytometry - Recurrent Colon Cancer, Recurrent Gastric Cancer
Phase 1CompletedCity of Hope Medical Center122011-12-222026-10-19
Vaccine Therapy With or Without Cryosurgery in Treating Patients With Residual, Relapsed, or Refractory B-Cell Non-Hodgkin Lymphoma
dendritic cell vaccine therapy, cryotherapy, pneumococcal polyvalent vaccine - Cutaneous B-cell Non-Hodgkin Lymphoma, Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue
Early Phase 1CompletedMayo Clinic162010-11-012020-01-14
ABT-888, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
temozolomide, veliparib, DNA methylation analysis - Brain and Central Nervous System Tumors
Phase 1CompletedSidney Kimmel Comprehensive Cancer Center at Johns Hopkins242009-07-132018-06-27
Sorafenib, Epirubicin, Ifosfamide, and Radiation Therapy Followed By Surgery in Treating Patients With High-Risk Stage II or Stage III Soft Tissue Sarcoma
epirubicin hydrochloride, ifosfamide, sorafenib tosylate - Sarcoma
Phase 1CompletedOHSU Knight Cancer Institute182009-02-012018-09-07
Laboratory-Treated T Cells and Ipilimumab in Treating Patients With Metastatic Melanoma
ipilimumab, cyclophosphamide, biopsy - Recurrent Melanoma, Stage IV Melanoma
Phase 1 / Phase 2CompletedFred Hutchinson Cancer Center102009-02-012017-04-19
Stereotactic Radiosurgery and Erlotinib in Treating Patients With Non-Small Cell Lung Cancer and Brain Metastases
erlotinib hydrochloride, immunoenzyme technique, laboratory biomarker analysis - Lung Cancer, Metastatic Cancer
Phase 1WithdrawnUniversity of California, San Francisco2009-01-012012-10-04
Paricalcitol in Treating Patients With Advanced Prostate Cancer and Bone Metastases
paricalcitol, immunoenzyme technique, laboratory biomarker analysis - Metastatic Cancer, Prostate Cancer
Phase 2TerminatedWake Forest University Health Sciences22009-01-012018-07-06
Trastuzumab, Cyclophosphamide, and Vaccine Therapy in Treating Patients With High-Risk or Metastatic Breast Cancer
allogeneic GM-CSF-secreting breast cancer vaccine, trastuzumab, cyclophosphamide - Breast Cancer
Phase 2CompletedSidney Kimmel Comprehensive Cancer Center at Johns Hopkins202008-12-012018-09-26
Topical Imiquimod and Abraxane in Treating Patients With Advanced Breast Cancer
imiquimod, Abraxane, laboratory biomarker analysis - Male Breast Cancer, Recurrent Breast Cancer
Phase 2CompletedUniversity of Washington152008-12-012018-01-02
Exercise Programs in Healthy Young Women at Increased Risk of Developing Breast Cancer
exercise intervention, counseling intervention, gas chromatography - Breast Cancer, Healthy, no Evidence of Disease
Not applicableCompletedAbramson Cancer Center at Penn Medicine1832008-10-012020-04-16
Donor Stem Cell Transplant, Pentostatin, and Total-Body Irradiation in Treating Patients With Hematological Cancer
cyclosporine, mycophenolate mofetil, pentostatin - Chronic Myeloproliferative Disorders, Leukemia
Phase 1 / Phase 2WithdrawnUniversity of Nebraska2008-09-012023-08-14
Vaccine Therapy in Treating Patients With Previously Treated Stage II or Stage III Breast Cancer
CpG oligodeoxynucleotide, HER-2/neu peptide vaccine, MUC-1 peptide vaccine - Breast Cancer
Early Phase 1CompletedMayo Clinic452008-08-282018-10-31
Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Carboplatin in Treating Patients With Stage IIIB, Stage IV, or Recurrent Non-Small Cell Lung Cancer
carboplatin, paclitaxel albumin-stabilized nanoparticle formulation, protein expression analysis - Lung Cancer
Phase 2CompletedGreg Otterson632008-08-142018-04-02
Blood Samples From Patients on a Clinical Trial to CINV During HSCT
immunoenzyme technique, laboratory biomarker analysis, medical chart review - Breast Cancer, Chronic Myeloproliferative Disorders
TerminatedOHSU Knight Cancer Institute92008-08-012017-05-09
Studying Blood Samples From Patients With Multiple Myeloma Who Were Treated With Thalidomide or Lenalidomide
gene expression analysis, reverse transcriptase-polymerase chain reaction, immunoenzyme technique - Multiple Myeloma and Plasma Cell Neoplasm
CompletedEastern Cooperative Oncology Group332008-07-042017-05-17
Anti-IMP3 Autoantibody and MicroRNA Signature Blood Tests in Finding Metastasis in Patients With Localized or Metastatic Kidney Cancer
gene expression analysis, protein expression analysis, diagnostic laboratory biomarker analysis - Kidney Cancer
CompletedCity of Hope Medical Center1552008-07-012017-12-08
Gemcitabine and Carboplatin Followed By Laboratory-Treated T Lymphocytes in Treating Patients With Metastatic or Locally Recurrent Epstein-Barr Virus-Positive Nasopharyngeal Cancer
autologous Epstein-Barr virus-specific cytotoxic T lymphocytes, carboplatin, gemcitabine hydrochloride - Head and Neck Cancer
Phase 2UnknownNational Cancer Centre, Singapore352008-07-012009-06-29

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Conditions studied

Breast Neoplasms (22)  ·  Carcinoma, Non-Small-Cell Lung (12)  ·  Lung Neoplasms (10)  ·  Head and Neck Neoplasms (8)  ·  Leukemia, Lymphocytic, Chronic, B-Cell (8)  ·  Lymphoma, B-Cell, Marginal Zone (8)  ·  Lymphoma, Follicular (8)  ·  Lymphoma, Mantle-Cell (8)  ·  Lymphoma, Non-Hodgkin (8)  ·  Precursor Cell Lymphoblastic Leukemia-Lymphoma (8)  ·  Breast Neoplasms, Male (7)  ·  Congenital Abnormalities (7)  ·  Carcinoma, Ovarian Epithelial (6)  ·  Leukemia (6)  ·  Lymphoma, Large B-Cell, Diffuse (6)

Sponsors

Memorial Sloan Kettering Cancer Center (9)  ·  City of Hope Medical Center (7)  ·  Case Comprehensive Cancer Center (5)  ·  Mayo Clinic (5)  ·  National Cancer Institute (NCI) (4)  ·  University of Washington (4)  ·  ECOG-ACRIN Cancer Research Group (3)  ·  National Cancer Centre, Singapore (3)  ·  OHSU Knight Cancer Institute (3)  ·  Roswell Park Cancer Institute (3)  ·  Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (3)  ·  Vanderbilt University Medical Center (3)  ·  Wake Forest University Health Sciences (3)  ·  Abramson Cancer Center at Penn Medicine (2)  ·  Barbara Ann Karmanos Cancer Institute (2)

Countries

United States (63)  ·  Canada (3)  ·  Singapore (3)  ·  United Kingdom (2)  ·  Belgium (1)  ·  France (1)  ·  Switzerland (1)

Top investigators

Svetomir Markovic, MD, PhD (3)  ·  Wendell G. Yarbrough, MD, FACS (3)  ·  Angela Davies, MD (2)  ·  Lupe Salazar (2)  ·  Toh Han Chong, MD, MBBS, MRCP (2)  ·  Vincent Chung, MD (2)  ·  Alan N. Houghton, MD (1)  ·  Alex A. Adjei, MD, PhD (1)  ·  Alison T. Stopeck, MD (1)  ·  Andrew D. Zelenetz, MD, PhD (1)  ·  Antonio Omuro, MD (1)  ·  Aude Chapuis (1)  ·  Barbara A Pockai, M.D. (1)  ·  Charles M. Rudin, MD, PhD (1)  ·  Christopher W. Ryan, MD (1)

Results publications

PMID 16469108, PMID 17551310, PMID 17570509, PMID 18090584, PMID 20063546, PMID 20400682, PMID 21285985, PMID 21677464, PMID 22044694, PMID 23243055, PMID 24386300, PMID 24987057, PMID 26123189, PMID 26130251, PMID 27269940, PMID 28114604, PMID 28679643, PMID 31319977, PMID 34615429, PMID 35135810, PMID 36326756

NIH funding

P30CA008748 (5), P30CA033572 (4), P30CA015083 (3), P30CA043703 (3), P30CA068485 (3), P30CA006973 (2), P30CA012197 (2), P30CA022453 (2), P30CA023074 (2), P30CA036727 (2), P30CA069533 (2), K12CA076930 (1), N01CM17101 (1), N01CN35158 (1), N01CN35160 (1)