39 completed, 18 unknown, 13 recruiting, 6 terminated. 23 Not applicable, 23 Phase 1, 18 Phase 2, 10 Early Phase 1, 6 Phase 4.
Follow ICG: new trials by email Literature Review of ICG trials Research Report on ICG
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Acute Cholecystitis Biliary Complications - ICG ICG - Acute Cholecystitis, Biliary Complications | Not applicable | Not yet recruiting | Hospital del Mar | 296 | 2027-01-01 | 2026-03-19 |
| Magnetic Sentinel Lymph Node Mapping in Gastric Cancer Gastrectomy, Indocyanine Green, Iron Conjugated Polymers in Saline Suspension - Gastric Adenocarcinoma | Phase 1 | Not yet recruiting | M.D. Anderson Cancer Center | 20 | 2026-12-31 | 2026-08-14 |
| Indocyanine Green With Near Infrared Imaging for Intraoperative Visualization of Head and Neck Squamous Cell Carcinoma Indocyanine green, Near-infrared fluorescence imaging - Head and Neck Squamous Cell Carcinoma | Recruiting | Washington University School of Medicine | 25 | 2026-09-30 | 2026-10-09 | |
| Comparing Intraoperative Indocyanine Green Fluorescence Imaging With Standard Clinical Assessment for Flap Perfusion in Head and Neck Reconstruction (VISION Trial) Indocyanine Green, Standard clinical perfusion assessment - Head and Neck Cancer (H&N), Free Tissue Flaps | Phase 4 | Recruiting | Region Skane | 244 | 2026-09-28 | 2026-09-29 |
| Fluorescence-Guided Surgical Resection for Reducing Unexpected Positive Margins in Patients With Sarcoma, SarcoSIGHT Trial Electronic Health Record Review, Fluorescence Imaging, Fluorescence-Guided Surgery - High Grade Sarcoma, Sarcoma | Phase 2 | Recruiting | City of Hope Medical Center | 22 | 2026-08-14 | 2026-10-16 |
| Application of Indocyanine Green Tracer in D2 Lymphadenectomy of Locally Advanced Gastric Cancer ICG administration - GASTRIC CANCER, Indocyanine Green (ICG) | Not applicable | Not yet recruiting | Hospital of Navarra | 102 | 2026-03-01 | 2025-03-24 |
| The Use of Near-Infrared Fluorescence Cholangiography With Indocyanine Green (ICG) in the Work Up of Neonatal Cholestasis Indocyanine Green - Biliary Atresia, Kasai | Early Phase 1 | Recruiting | University of Alabama at Birmingham | 15 | 2026-01-23 | 2026-02-18 |
| Accuracy of Indocyanine Green (ICG) Fluorescence Imaging in Giant Cell Tumor of Bone Surgery Indocyanine Green - Giant Cell Tumor of Bone | Phase 4 | Recruiting | Shanghai Jiao Tong University Affiliated Sixth People's Hospital | 40 | 2026-01-02 | 2026-01-05 |
| Clinical Trial to Evaluate Post-Operative Outcomes of Ureteral Stent vs Ureteral Stent Free Radical Cystectomy Ureteral Stent Placement, No Ureteral Stent, Indocyanine Green with Fluorescence Imaging - Bladder Cancer, Muscle-Invasive Bladder Carcinoma | Not applicable | Recruiting | Thomas Jefferson University | 70 | 2025-12-23 | 2026-02-17 |
| Indocyanine Green Fluoroscopy and SPY Angiography for the Assessment of Lymphatic Structure in Breast Cancer Patients at Risk for Breast Cancer-Related Lymphedema Fluid Therapy, Indocyanine Green, Questionnaire Administration - Breast Cancer-Related Lymphedema, Breast Carcinoma | Not applicable | Withdrawn | City of Hope Medical Center | 2025-08-14 | 2025-09-17 | |
| Implementation of Indocyanine Green to Identify Sentinel Lymph Nodes During Surgery for Breast Cancer Technetium (99mTc), Indocyanine Green, Sentinel lymph node biopsy - Breast Cancer, Sentinel Lymph Node Biopsy (SLNB) | Not applicable | Recruiting | Isabelle Henskens | 1760 | 2025-04-18 | 2026-06-25 |
| Assessing CSF Flow Dynamics in Pediatric Hemorrhagic Hydrocephalus fCTOT cap, NIRF planar imaging, ICG - Post-hemorrhagic Hydrocephalus (PHH) | Phase 1 | Recruiting | Eva Sevick | 20 | 2025-01-14 | 2025-05-29 |
| Evaluation of Neuroma Perfusion with Indocyanine Green Fluorescence Angiography Indocyanine green - Neuroma, Neuroma Amputation | Phase 4 | Withdrawn | Northwestern University | 2024-12-28 | 2025-01-01 | |
| Impact of Intraoperative ICG on Functional Outc in RARP ICG - Prostate Adenocarcinoma | Early Phase 1 | Recruiting | University of California, Irvine | 400 | 2024-07-12 | 2026-03-03 |
| Indocyanine Green (ICG) Guided Sentinel Lymph Node Mapping for Pediatric Visceral Solid Tumors Indocyanine Green - Solid Tumor | Early Phase 1 | Recruiting | St. Jude Children's Research Hospital | 25 | 2023-10-24 | 2026-05-04 |
| Intraoperative Parathyroid Gland (PTG) Identification Using a Hand-Held Imager (HHI) Parathyroid auto-fluorescence imaging, Indocyanine green - Thyroid Disease, Thyroid Surgery | Phase 1 | Terminated | OPTOSURGICAL, LLC | 44 | 2023-09-01 | 2026-09-22 |
| Feasibility and Utility of Artificial Intelligence (AI) / Machine Learning (ML) - Driven Advanced Intraoperative Visualization and Identification of Critical Anatomic Structures and Procedural Phases in Laparoscopic Cholecystectomy ICG - Cholecystitis, Cholelithiasis | Not applicable | Unknown | Activ Surgical | 120 | 2023-08-01 | 2024-02-21 |
| Fluorescence Imaging With Indocyanine Green(ICG) in Endoscopic Spinal Surgery Indocyanine Green, Fluorescence imaging - Disc Herniation | Phase 1 / Phase 2 | Completed | Zhongnan Hospital | 40 | 2023-04-11 | 2025-12-19 |
| Comparison of ICG Microangiography and Conventional Angiography in Severe Frostbite Indocyanine Green Angiogram - Frostbite | Completed | HealthPartners Institute | 8 | 2023-02-03 | 2026-07-30 | |
| Near-infrared Imaging With Indocyanine Green for Detection of Peritoneal Metastases for Gastric Adenocarcinoma. Indocyanine green - Gastric Cancer, Gastric Adenocarcinoma | Phase 2 | Terminated | Laval University | 11 | 2022-12-15 | 2024-04-02 |
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Breast Neoplasms (15) · Stomach Neoplasms (7) · Neoplasms (6) · Carcinoma, Hepatocellular (4) · Cholecystitis (4) · Lung Neoplasms (4) · Arthritis, Rheumatoid (3) · Melanoma (3) · Uterine Cervical Neoplasms (3) · Cholecystitis, Acute (2) · Cholestasis (2) · Esophageal Neoplasms (2) · Fractures, Bone (2) · Head and Neck Neoplasms (2) · Hypocalcemia (2)
Jules Bordet Institute (6) · University of Pennsylvania (5) · Huazhong University of Science and Technology (4) · Centre Hospitalier Universitaire Saint Pierre (3) · Chinese Academy of Sciences (3) · M.D. Anderson Cancer Center (3) · University of Rochester (3) · Washington University School of Medicine (3) · City of Hope Medical Center (2) · Fujian Medical University (2) · Massachusetts General Hospital (2) · National Taiwan University Hospital (2) · Northwestern University (2) · Oxford University Hospitals NHS Trust (2) · St. Jude Children's Research Hospital (2)
United States (37) · China (16) · Belgium (9) · Netherlands (3) · Spain (3) · Canada (2) · Taiwan (2) · United Kingdom (2) · Australia (1) · Denmark (1) · France (1) · Germany (1) · Qatar (1) · South Korea (1) · Sweden (1)
Ding-Cheng Chan (2) · Isabelle Veys, MD (2) · Jean-Paul Belgrado (2) · Sunil Singhal, MD (2) · Thomas Barnes, MBChB (2) · Alda Tam, MD (1) · Alexandra Lacey, MD (1) · Alexandre Brind'Amour, MD (1) · Ali Zarrinpar, MD, PhD (1) · Andrew Davidoff, MD (1) · Andrew T. Chan, MD, MPH (1) · Annemiek Doeksen, MD, PhD (1) · Antoine Digonnet, MD (1) · Bharat Panuganti, MD, FACS (1) · Chang-Ming Huang, MD (1)
PMID 24358319, PMID 27497181, PMID 17013643, PMID 21613624, PMID 25106680, PMID 25304271, PMID 27499979, PMID 27566635, PMID 27586634, PMID 28249726, PMID 28387632, PMID 28623992, PMID 28950327, PMID 29049798, PMID 29290809, PMID 30028985, PMID 30327136, PMID 31188797, PMID 31482242, PMID 32101269, PMID 32224746, PMID 33094400, PMID 33214476, PMID 33754215, PMID 34905086, PMID 35340114, PMID 36686792, PMID 36728303, PMID 36809077, PMID 37121582, PMID 37121591, PMID 37178368, PMID 37194488, PMID 37554762, PMID 37939147, PMID 37973806, PMID 38954670, PMID 40859341, PMID 42342397
P30CA033572 (2), R01AR056702 (2), 2025 (1), P30CA016672 (1), R01CA128919 (1), R01HL092923 (1), R01NS126437 (1), R44CA206754 (1), U54CA136404 (1), U54CA136465 (1)