5 completed, 4 recruiting, 4 terminated, 3 not yet recruiting. 11 Not applicable, 4 Phase 2, 2 Phase 3, 1 Phase 1, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 11 | Terminated 4, Completed 3, Not yet recruiting 2, Unknown 2 |
| Phase 2 | 4 | Recruiting 3, Completed 1 |
| Phase 3 | 2 | Completed 1, Recruiting 1 |
| Phase 1 | 1 | Recruiting 1 |
| Phase 4 | 1 | Recruiting 1 |
Follow Hyperbaric oxygen treatment: new trials by email Literature Review of Hyperbaric oxygen treatment trials Research Report on Hyperbaric oxygen treatment
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of Hyperbaric Oxygen Therapy in Improving Nab-paclitaxel-Induced Peripheral Neuropathy Hyperbaric oxygen treatment, Standard Care (in control arm) - Breast Cancer, CIPN - Chemotherapy-Induced Peripheral Neuropathy | Phase 2 / Phase 3 | Recruiting | Guangdong Provincial People's Hospital | 160 | 2026-09-29 | 2026-09-30 |
| Long-Term Outcomes Following HBOT Hyperbaric Oxygen Therapy (HBOT) - Traumatic Brain Injury, Post-Concussive Symptoms | Phase 2 | Recruiting | Summit Hyperbarics and Wellness | 35 | 2026-06-18 | 2026-07-28 |
| Adjunctive Hyperbaric Oxygen Treatment for Patients With Necrotizing Soft-Tissue Infection (HOT-NSTI Trial). Hyperbaric oxygen treatment, Standard of Care (Investigator Choice) - Necrotizing Soft Tissue Infection | Phase 4 | Recruiting | Ole Hyldegaard | 1480 | 2026-04-04 | 2026-09-04 |
| Effect of Hyperbaric Oxygen Therapy(HBOT) on Patients With Sudden Sensorineural Hearing Loss(SSNHL) and Coagulation Function Hyperbaric oxygen treatment - Sudden Sensorineural Hearing Loss (SSNHL), Hyperbaric Oxygen Therapy | Not yet recruiting | Sun Yuting | 1309 | 2025-06-01 | 2025-05-14 | |
| A Clinical Study to Explore the Efficacy and Safety of Hyperbaric Oxygen in the Neoadjuvant Treatment of Hormone Receptor Positive Breast Cancer Patients Hyperbaric oxygen treatment - Breast Cancers | Not applicable | Not yet recruiting | Guangdong Provincial People's Hospital | 55 | 2025-02-15 | 2025-02-13 |
| A Phase II Single-Arm Clinical Study to Explore the Efficacy and Safety of Hyperbaric Oxygen in the Neoadjuvant Treatment of Triple-Negative and HER2+ Breast Cancer Patients Hyperbaric oxygen treatment - Breast Cancers | Not applicable | Not yet recruiting | Guangdong Provincial People's Hospital | 348 | 2025-02-12 | 2025-02-13 |
| A Phase II Single-Arm Clinical Study to Explore the Efficacy and Safety of Hyperbaric Oxygen in the Neoadjuvant Treatment of Breast Cancer Patients hyperbaric oxygen treatment - Breast Cancers | Phase 1 / Phase 2 | Recruiting | Guangdong Provincial People's Hospital | 161 | 2025-02-01 | 2025-04-01 |
| Hyperbaric Oxygen Therapy for Post-Concussion Syndrome Hyperbaric Oxygen Treatment, Placebo gas - Post-Concussion Syndrome | Not applicable | Completed | University of Texas Southwestern Medical Center | 12 | 2023-03-01 | 2025-10-14 |
| The Effect of Hyperbaric Oxygen Treatment in Patients With Osteoradionecrosis. Hyperbaric oxygen treatment - Osteoradionecrosis | Not applicable | Unknown | Göteborg University | 120 | 2019-03-19 | 2021-06-22 |
| Hyperbaric Oxygenation Treatment and Quality of Life Hyperbaric oxygen treatment - Cancer | Completed | University of Bergen | 137 | 2018-08-31 | 2023-12-14 | |
| HBOT in Fibromyalgia Hyperbaric Oxygen Treatment - Fibromyalgia, Chronic Pain | Not applicable | Completed | University Health Network, Toronto | 16 | 2015-11-01 | 2019-05-17 |
| Effect of Hyperbaric Oxygen on Functional Connectivity in Patients With Cerebral Small Vessel Disease hyperbaric oxygen treatment - Cerebral Small Vessel Diseases | Not applicable | Terminated | St. Luke's Hospital, Chesterfield, Missouri | 6 | 2014-11-01 | 2017-10-27 |
| Effect of HBO on Functional Connectivity of Resting State Networks in Patients With Cerebral Small Vessel Disease Hyperbaric Oxygen Treatment - Encephalopathy, White Matter Hyperintensities | Not applicable | Terminated | St. Luke's Hospital, Chesterfield, Missouri | 20 | 2014-09-16 | 2017-10-30 |
| Stem Cell Quantification In Peripheral Blood After Hyperbaric Oxygen Therapy Treatments Hyperbaric Oxygen Treatment - Changes in Peripheral Blood Population Numbers and Type. | Unknown | Restorix Research Institute, LLLP | 8 | 2012-12-01 | 2012-12-04 | |
| Effects of Hyperbaric Oxygen Therapy on Surgical Wound Healing Hyperbaric oxygen treatment, Air sham - Edema, Ecchymosis | Not applicable | Unknown | Restorix Research Institute, LLLP | 164 | 2011-08-01 | 2012-12-05 |
| Hyperbaric Oxygen Treatment Ameliorates Insulin Resistance Hyperbaric Oxygen Treatment - Obesity, Type 2 Diabetes | Not applicable | Completed | University of Adelaide | 20 | 2011-04-01 | 2013-09-19 |
| Hyperbaric Oxygen Treatment as Adjuvant Treatment for Frost Injury Hyperbaric oxygen treatment - Wound (Morphologic Abnormality) | Not applicable | Terminated | Oslo University Hospital | 20 | 2011-01-01 | 2021-03-04 |
| Hyperbaric Oxygen in Lower Leg Trauma Hyperbaric Oxygen Treatment - Tibial Fracture, Soft Tissue Injury | Phase 2 / Phase 3 | Completed | Bayside Health | 120 | 2007-02-13 | 2023-09-05 |
| An Evaluation of Hyperbaric Treatments for Children With Cerebral Palsy Hyperbaric Oxygen Treatment, Hyperbaric Air Treatment - Cerebral Palsy, Cerebral Palsy, Spastic | Not applicable | Terminated | Dayton Children's Hospital | 49 | 2005-08-01 | 2014-08-28 |
Breast Neoplasms (4) · Post-Concussion Syndrome (2) · Wounds and Injuries (2) · Anxiety Disorders (1) · Brain Diseases (1) · Brain Injuries, Traumatic (1) · Cerebral Palsy (1) · Cerebral Small Vessel Diseases (1) · Chronic Pain (1) · Crush Injuries (1) · Depression (1) · Diabetes Mellitus, Type 2 (1) · Ecchymosis (1) · Edema (1) · Fibromyalgia (1)
Guangdong Provincial People's Hospital (4) · Restorix Research Institute, LLLP (2) · St. Luke's Hospital, Chesterfield, Missouri (2) · Bayside Health (1) · Dayton Children's Hospital (1) · Göteborg University (1) · Ole Hyldegaard (1) · Oslo University Hospital (1) · Summit Hyperbarics and Wellness (1) · Sun Yuting (1) · University Health Network, Toronto (1) · University of Adelaide (1) · University of Bergen (1) · University of Texas Southwestern Medical Center (1)
United States (8) · China (5) · Norway (3) · Australia (2) · Sweden (2) · Austria (1) · Belgium (1) · Canada (1) · Chile (1) · Czechia (1) · India (1) · Italy (1) · Portugal (1)
John D. Davidson, MD (2) · Bryan Sires, MD, FACS (1) · Daniel J Lacey, MD, PhD (1) · Ian L Millar, MBBS (1) · James Berry, M.D. (1) · Knut Ar Kirkeboen, MD Professor (1) · Kun Wang (1) · Kun Wang, PhD (1) · Leonie K Heilbronn, Phd (1) · May Aa Hauken, Professor (1) · Owen Williamson (1) · Peter Cameron (1) · Rita Katznelson (1)
PMID 23071074, PMID 33594439, PMID 34779920, PMID 35320424, PMID 37449715, PMID 42296275
2025 (1)