6 completed, 2 unknown, 1 recruiting, 1 terminated. 4 Phase 1, 3 Phase 3, 2 Early Phase 1, 2 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Completed 2, Unknown 2 |
| Phase 3 | 3 | Completed 2, Terminated 1 |
| Early Phase 1 | 2 | Completed 1, Withdrawn 1 |
| Phase 2 | 2 | Completed 1, Unknown 1 |
| Phase 4 | 1 | Recruiting 1 |
Follow hydrocortisone acetate: new trials by email Literature Review of hydrocortisone acetate trials Research Report on hydrocortisone acetate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Sore Throat After Open Neck Elective Surgery Hydrocortisone Acetate 1% Ointment, Lidocaine hydrochloride 0,05% with chlorhexidine - Postoperative Sore Throat, Cough, Hoarseness, Thyroid and Parathyroid Surgery | Phase 4 | Recruiting | Saint Petersburg State University, Russia | 764 | 2025-09-15 | 2026-04-13 |
| A Study of Opevesostat (MK-5684) in China Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC) (MK-5684-001) Opevesostat, Dexamethasone, Fludrocortisone - Prostatic Neoplasms, Metastatic Castration-Resistant Prostate Cancer | Phase 1 | Completed | Merck Sharp & Dohme LLC | 14 | 2024-01-30 | 2026-03-19 |
| Topical Cream SNG100 for Treatment in Moderate Atopic Dermatitis Subjects. Hydrocortisone Acetate 1% Cream, Mometasone Furoate, SNG100 - Atopic Dermatitis | Phase 1 | Unknown | Seanergy Dermatology Ltd. | 66 | 2021-01-01 | 2020-11-04 |
| Phase 3 Study to Evaluate the Safety and Efficacy of Hydrocortisone Acetate Suppositories Twice daily 90 mg hydrocortisone acetate suppository administered with Sephure applicator, Once daily 90 mg hydrocortisone acetate or placebo suppository administered with Sephure applicator, Twice daily placebo suppository administered with Sephure applicator - Ulcerative Proctitis | Phase 3 | Completed | Cristcot HCA LLC | 200 | 2020-12-10 | 2026-08-06 |
| Epinephrine and Cortisol in Depression Hydrocortisone Acetate (CORT), Epinephrine Sulfate (EPI), Placebo (PLB) - Depression | Early Phase 1 | Withdrawn | Stanford University | 2020-12-01 | 2021-10-06 | |
| Effectivness of Topical Tacrolimus Monotherapy in Patients With Vitiligo Tacrolimus 0.03% Ointment, Hydrocortisone Acetate 1% Ointment - Vitiligo, Tacrolimus | Phase 1 / Phase 2 | Unknown | Sohag University | 100 | 2017-10-01 | 2017-11-30 |
| The Effect of Cortisol Administration on Neural Correlates of Emotion in Depression Hydrocortisone acetate, Placebo - Depression | Early Phase 1 | Completed | Stanford University | 192 | 2016-07-01 | 2021-10-22 |
| Pharmacokinetics and Bioavailability of Hydrocortisone Acetate Suppositories Cortenema, Hydrocortisone Acetate - Healthy | Phase 1 | Completed | Cristcot LLC | 16 | 2016-03-01 | 2017-07-28 |
| Safety and Efficacy of Hydrocortisone and Lidocaine Treatment of Grade I and II Hemorrhoids Hydrocortisone acetate and lidocaine hydrochloride, Placebo control, Hydrocortisone acetate - Hemorrhoids | Phase 2 | Completed | Citius Pharmaceuticals, Inc. | 211 | 2015-05-01 | 2016-02-24 |
| Low Doses Corticosteroids as Adjuvant Therapy for the Treatment of Severe H1N1 Flu hydrocortisone, isotonic saline - Pneumonia, Viral, Influenza in Humans | Phase 3 | Terminated | University of Versailles | 40 | 2010-03-01 | 2014-12-18 |
| Chemotherapy Plus Hormone Therapy Versus Androgen Suppression in Treating Patients With Metastatic or Unresectable Prostate Cancer Bicalutamide, Doxorubicin hydrochloride, Estramustine Phosphate Sodium - Prostate Cancer | Phase 3 | Completed | M.D. Anderson Cancer Center | 306 | 1996-08-01 | 2018-10-31 |
Depression (2) · Prostatic Neoplasms (2) · Acute Lung Injury (1) · Cough (1) · Dermatitis, Atopic (1) · Hemorrhoids (1) · Hoarseness (1) · Inflammation (1) · Influenza, Human (1) · Pneumonia, Viral (1) · Respiratory Distress Syndrome (1) · Thyroid Diseases (1) · Vitiligo (1)
Stanford University (2) · Citius Pharmaceuticals, Inc. (1) · Cristcot HCA LLC (1) · Cristcot LLC (1) · M.D. Anderson Cancer Center (1) · Merck Sharp & Dohme LLC (1) · Saint Petersburg State University, Russia (1) · Seanergy Dermatology Ltd. (1) · Sohag University (1) · University of Versailles (1)
United States (3) · China (2) · France (2) · Russia (2) · Bulgaria (1) · Denmark (1) · Egypt (1) · Georgia (1) · Germany (1) · India (1) · Italy (1) · Jordan (1) · Lebanon (1) · Libya (1) · Moldova (1)
Keith Sudheimer, Ph.D. (2) · Alan S. Lader, Ph.D. (1) · Charles Mayaud (1) · Christian Brun Buisson, MD (1) · Christian Perronne (1) · Djillali Annane, MD,PhD (1) · Jennifer Davagian (1) · Marck C Ensign (1) · Ramadan Saleh, MD (1) · Randall E. Millikan, MD, PhD (1) · Sergey M. Efremov, MD, PhD (1) · Yuval Ramot, Prof. (1)
2019 (1), P30CA016672 (1)