heme arginate: Clinical Trials

6 trials of heme arginate, newest first

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6 completed. 6 Phase 2, 2 Phase 1.

By phase and status

PhaseTrialsStatus
Phase 26Completed 6
Phase 12Completed 2

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Trials (filtered) newest first · largest first

All 6 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
The Effects of Intravenous Heme Arginate on Heme Oxygenase-1 Expression (HO-1) and Oxidative Stress in the Human Heart
Heme arginate 3mg/kg, Heme arginate 1mg/kg, Placebo - Myocardial Ischemia
Phase 2CompletedMartin Andreas, M.D.312015-03-292021-02-15
Heme Arginate in Cardiac Surgery Patients
Heme arginate - Acute Kidney Injury
Phase 2CompletedUniversity of Edinburgh202014-10-172024-09-19
Hemin to Prevent Post-ERCP (Endoscopic Retrograde Cholangiopancreatography) Acute Pancreatitis
Hemin, placebo - Post-ERCP Acute Pancreatitis
Phase 2CompletedErasme University Hospital2842012-04-012021-07-07
Does Heme Oxygenase-1 Induction Ameliorate Cardiac Injury After Myocardial Infarction?
Heme arginate - Acute Myocardial Infarction
Phase 1 / Phase 2CompletedUniversity Medical Center Groningen152007-07-012010-09-20
Studies in Porphyria III: Heme and Tin Mesoporphyrin in Acute Porphyrias
heme arginate, tin mesoporphyrin - Porphyria
Phase 2CompletedNational Center for Research Resources (NCRR)321997-09-012005-06-24
Phase I/II Study of Heme Arginate and Tin Mesoporphyrin for Acute Porphyria
heme arginate, tin mesoporphyrin - Porphyria
Phase 1 / Phase 2CompletedNational Center for Research Resources (NCRR)591993-07-012005-06-24

Conditions studied

Metabolism, Inborn Errors (2)  ·  Porphyrias (2)  ·  Rare Diseases (2)  ·  Reperfusion Injury (2)  ·  Acute Coronary Syndrome (1)  ·  Acute Kidney Injury (1)  ·  Myocardial Ischemia (1)  ·  Non-ST Elevated Myocardial Infarction (1)  ·  Porphyria, Acute Intermittent (1)

Sponsors

National Center for Research Resources (NCRR) (2)  ·  Erasme University Hospital (1)  ·  Martin Andreas, M.D. (1)  ·  University Medical Center Groningen (1)  ·  University of Edinburgh (1)

Countries

Austria (1)  ·  Belgium (1)  ·  Netherlands (1)  ·  Taiwan (1)  ·  United Kingdom (1)  ·  United States (1)

Top investigators

Karl Elmo Anderson (2)  ·  Alfred Kocher, M.D. (1)  ·  Arnaud Lemmers, MD,PhD (1)  ·  David C Kluth, MD (1)  ·  Jeremy Hughes, MD (1)  ·  Prof. F. Zijlstra, MD, PhD (1)  ·  Vipin Zamvar, MD (1)

Results publications

PMID 30354231, PMID 38431445

NIH funding

2014 (1)