12 unknown, 4 recruiting, 3 completed, 2 terminated. 22 Phase 2, 2 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 22 | Unknown 12, Recruiting 4, Completed 3, Terminated 2, Not yet recruiting 1 |
| Phase 3 | 2 | Completed 1, Recruiting 1 |
| Phase 1 | 1 | Unknown 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Neoadjuvant and Adjuvant Therapy Studies of Sintilimab Combined With Chemotherapy With or Without Ipilimumab N01 in Resectable Gastric/Gastroesophageal Junction Adenocarcinoma tegafur, Gimeracil and Oteracil Potassium Capsules, Sintilimab Placebo, Sintilimab - Resectable Gastric/Gastroesophageal Junction Adenocarcinoma | Phase 2 / Phase 3 | Recruiting | Innovent Biopharmaceutical Technology (Hangzhou) Co., LTD. | 720 | 2026-07-31 | 2026-08-14 |
| Perioperative Therapy for HER2-negative Hepatoid Adenocarcinoma of Stomach Perioperative treatment with albumin-bound paclitaxel, oxaliplatin, tegafur,gimeracil and oteracil porassium capsules and sintilimab. - Hepatoid Adenocarcinoma of Stomach | Phase 2 | Recruiting | Peking University Cancer Hospital & Institute | 30 | 2025-09-18 | 2025-12-02 |
| RC48 Combined With Adebrelimab, Apatinib and S-1 as Neoadjuvant Therapy in Locally Advanced Gastric Cancer RC48, Adebrelimab, Apatinib - Gastric Cancer/Gastroesophageal Junction Adenocarcinoma | Phase 2 | Not yet recruiting | The First Affiliated Hospital with Nanjing Medical University | 32 | 2024-05-01 | 2024-05-13 |
| Consolidation of Toripalimab After Chemoradiotherapy in Elderly Esophageal Cancer (EC-CRT-007) S-1, Toripalimab, Intensity-modulated radiotherapy - Locally Advanced Esophageal Squamous Cell Carcinoma | Phase 2 | Recruiting | Sun Yat-sen University | 140 | 2024-03-01 | 2024-03-12 |
| A LM-302 Combination With Other Anti-Tumor Therapies Phase ll Study LM-302, Toripalimab, Capecitabine - Malignant Neoplasms of Digestive Organs | Phase 2 | Recruiting | LaNova Medicines Zhejiang Co., Ltd. | 632 | 2023-07-27 | 2026-10-19 |
| Quintuple Method for Treatment of Multiple Refractory Colorectal Liver Metastases Oxaliplatin, S1, Cetuximab - For Patients With Colorectal Cancer Liver Metastases Who Were Not Able to Curative Surgical Resection.Focused on the Treatment Effect With the Quintuple Method | Phase 2 | Unknown | Liaoning Cancer Hospital & Institute | 100 | 2023-03-15 | 2023-03-20 |
| Fruquintinib Plus S-1 and Raltitrexed (RSF) for MCRC Fruquintinib, S-1, raltitrexed - Fruquintinib, S-1 | Phase 2 | Unknown | Meng Qiu | 66 | 2023-02-20 | 2025-01-22 |
| Effect and Safety of Envafolimab Combined With Endostar/S-1 in Second-line of Advanced Non-small Cell Lung Cancer Envafolimab plus Endostar and S-1, Envafolimab plus Endostar, Envafolimab plus S-1 - Carcinoma, Non-Small-Cell Lung | Phase 2 | Unknown | Anhui Chest Hospital | 45 | 2022-09-18 | 2022-09-07 |
| A Phase II Study of Gimatecan (ST1481) in Locally Advanced or Metastatic Pancreatic Cancer Gimatecan, tegafur, gimeracil and oteracil potassium, gemcitabine - Pancreatic Cancer | Phase 2 | Unknown | Lee's Pharmaceutical Limited | 60 | 2020-12-01 | 2020-10-01 |
| CCRT Followed by Tegafur, Gimeracil and Oteracil Potassium in Cervical Cancer Tegafur, Gimeracil and Oteracil Potassium Capsules (one drug) - Cervical Cancer, Chemotherapy | Phase 1 / Phase 2 | Unknown | Peking Union Medical College Hospital | 200 | 2020-04-15 | 2020-03-19 |
| Tripletrumab Combined With Oxaliplatin and Teggio (SOX) in First-line Treatment of Gastric and Gastroesophageal Junction Adenocarcinoma Toripalimab combined with oxaliplatin and Tegafur,Gimeracil and Oteracil Porassium Capsules - Gastric Cancer | Phase 2 | Unknown | RenJi Hospital | 20 | 2020-02-01 | 2019-12-17 |
| Trial of Neoadjuvant Chemotherapy With S1 Plus Paclitaxel-albumin on Pancreatic Cancer S1,, Paclitaxel-albumin - Pancreatic Cancer, Neoadjuvant Chemotherapy | Phase 2 | Terminated | Zhejiang Provincial People's Hospital | 40 | 2017-11-20 | 2021-01-08 |
| Apatinib Combined With SOX Neoadjuvant Therapy for Locally Advanced Gastric Cancer ApatinibMesylateTablets - Apatinib Combined, SOX | Phase 2 | Unknown | Chang-Ming Huang, Prof. | 50 | 2017-09-01 | 2020-02-05 |
| The Clinical Study of Apatinib Plus S1 for Patients With Advanced Non-squamous Head and Neck Cancer Apatinib, S1 - Head and Neck Neoplasms | Phase 2 | Unknown | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 30 | 2016-10-01 | 2016-10-24 |
| Endostar Combined With MPFC Adjuvant Treatment of Esophageal Cancer Clinical Trial "Endostar", Liposo, cisplatin - Esophageal | Phase 2 | Terminated | The First Affiliated Hospital with Nanjing Medical University | 70 | 2016-04-01 | 2022-07-29 |
| Combined Use of Raltitrexed and S-1 as Treatment for Patients With Metastasizing Colorectal Cancer Raltitrexed and S-1 - Metastatic Colon Cancer | Phase 2 | Unknown | Fudan University | 82 | 2015-12-25 | 2017-10-02 |
| Efficacy and Safety of Nab-Paclitaxel Plus S-1 in the First-line Treatment of Advanced Pancreatic Cancer Nab-paclitaxel and S-1 - Advanced Pancreatic Cancer | Phase 2 | Completed | Aiping Zhou | 32 | 2015-05-11 | 2021-02-01 |
| Study of Oxaliplatin, Irinotecan, and S-1 in Biliary Tract Cancer Oxaliplatin, Irinotecan, S-1 - Biliary Tract Neoplasm | Phase 2 | Unknown | Hallym University Medical Center | 31 | 2015-03-01 | 2017-08-23 |
| Study of Oxaliplatin, Irinotecan, and S-1 in Gastric Cancer Oxaliplatin, Irinotecan, S-1(OIS) - Stomach Neoplasm | Phase 2 | Completed | Hallym University Medical Center | 44 | 2015-02-01 | 2017-08-23 |
| DC-CIK In Combination With Chemotherapy ( Gio / Oxaliplatin or Cisplatin ) Versus First-line Chemotherapy for Locally Advanced Unresectable or Metastatic Gastric Adenocarcinoma Randomized Controlled Phase II Clinical Study of Treatment autologous dendritic cells co-cultured with cytokine-induced killer cells, Gimeracil and Oteracil Porassium Capsules, Oxaliplatin - Gastric Cancer | Phase 2 | Unknown | Beijing Biohealthcare Biotechnology Co.,Ltd | 80 | 2014-11-01 | 2015-07-21 |
Showing 20 of 22. Sign in to see all of them.
Stomach Neoplasms (5) · Pancreatic Neoplasms (2) · Biliary Tract Neoplasms (1) · Carcinoma, Non-Small-Cell Lung (1) · Colonic Neoplasms (1) · Esophageal Squamous Cell Carcinoma (1) · Head and Neck Neoplasms (1) · Rectal Neoplasms (1) · Uterine Cervical Neoplasms (1)
Hallym University Medical Center (2) · The First Affiliated Hospital with Nanjing Medical University (2) · Aiping Zhou (1) · Anhui Chest Hospital (1) · Beijing Biohealthcare Biotechnology Co.,Ltd (1) · Cancer Institute and Hospital, Chinese Academy of Medical Sciences (1) · Chang-Ming Huang, Prof. (1) · Clinical Research Support Center Kyush (1) · Fudan University (1) · Hebei Medical University (1) · Innovent Biopharmaceutical Technology (Hangzhou) Co., LTD. (1) · LaNova Medicines Zhejiang Co., Ltd. (1) · Lee's Pharmaceutical Limited (1) · Liaoning Cancer Hospital & Institute (1) · Meng Qiu (1)
China (15) · South Korea (2) · Japan (1)
Dae Young Zang, MD, PhD (2) · Aiping Zhou (1) · Aiping Zhou, Doctor (1) · Chunmei Bai (1) · Deliang Fu (1) · Gu Yanhong, PI (1) · Haijiao Yan (1) · Haiping Jiang (1) · Hao Xu, Ph.D (1) · Jiafu Ji, MD (1) · Jieer Ying (1) · Jin Li (1) · Jing Dai (1) · Jun Zhou (1) · Ke Hu, MD (1)
PMID 19331206, PMID 21183517, PMID 26884585, PMID 29372461, PMID 32583567, PMID 33567129, PMID 34241629, PMID 34351356, PMID 35419831, PMID 36990609, PMID 37195667, PMID 37501640, PMID 38022664, PMID 40022044, PMID 41816563