26 completed, 7 terminated, 2 withdrawn, 1 active not recruiting. 37 Phase 1, 11 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 37 | Completed 26, Terminated 7, Withdrawn 2, Active not recruiting 1, Unknown 1 |
| Phase 2 | 11 | Completed 7, Terminated 3, Unknown 1 |
Follow gene expression analysis: new trials by email Literature Review of gene expression analysis trials Research Report on gene expression analysis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pomalidomide, Bortezomib, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma pomalidomide, bortezomib, dexamethasone - Refractory Multiple Myeloma | Phase 1 / Phase 2 | Completed | Mayo Clinic | 50 | 2011-09-01 | 2020-04-17 |
| Olaparib and Temozolomide in Treating Patients With Relapsed Glioblastoma olaparib, temozolomide, gene expression analysis - Brain and Central Nervous System Tumors | Phase 1 | Completed | Cancer Research UK | 34 | 2011-07-01 | 2018-02-05 |
| Azadirachta Indica in Treating Patients With Chronic Lymphocytic Leukemia laboratory biomarker analysis, western blotting, gene expression analysis - Refractory Chronic Lymphocytic Leukemia, Stage II Chronic Lymphocytic Leukemia | Phase 1 | Withdrawn | Roswell Park Cancer Institute | 2010-12-01 | 2014-01-13 | |
| Panobinostat and Fluorouracil Followed By Leucovorin Calcium in Treating Patients With Stage IV Colorectal Cancer Who Did Not Respond to Previous Fluorouracil-Based Chemotherapy panobinostat, fluorouracil, leucovorin calcium - Recurrent Colon Cancer, Recurrent Rectal Cancer | Phase 1 | Terminated | University of Southern California | 7 | 2010-10-01 | 2015-05-27 |
| Differentiation Therapy With Decitabine in Treating Patients With Myelodysplastic Syndrome flow cytometry, DNA methylation analysis, cytogenetic analysis - Chronic Myelomonocytic Leukemia, de Novo Myelodysplastic Syndromes | Phase 1 / Phase 2 | Completed | Case Comprehensive Cancer Center | 25 | 2010-07-01 | 2019-03-04 |
| Low-Dose Azacitidine, Lenalidomide, and Low-Dose Dexamethasone in Relapsed or Refractory Multiple Myeloma azacitidine, lenalidomide, dexamethasone - Refractory Multiple Myeloma | Phase 1 / Phase 2 | Completed | Case Comprehensive Cancer Center | 45 | 2010-06-01 | 2020-11-16 |
| Aspirin Mouthwash in Treating Patients With Oral Leukoplakia acetylsalicylic acid, gene expression analysis, protein expression analysis - Precancerous Condition | Phase 1 | Completed | Institute of Head and Neck Studies and Education, United Kingdom | 40 | 2010-02-01 | 2013-08-12 |
| Panobinostat and Epirubicin in Treating Patients With Metastatic Malignant Solid Tumors epirubicin hydrochloride, panobinostat, gene expression analysis - Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | Completed | University of California, San Francisco | 40 | 2009-09-13 | 2017-03-24 |
| ABT-888, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme temozolomide, veliparib, DNA methylation analysis - Brain and Central Nervous System Tumors | Phase 1 | Completed | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 24 | 2009-07-13 | 2018-06-27 |
| Studying Biomarkers in Tumor Tissue and Blood Samples From Patients Undergoing Chemotherapy and Radiation Therapy for Stage II or Stage III Rectal Cancer That Can Be Removed By Surgery systemic chemotherapy, RNA analysis, gene expression analysis - Colorectal Cancer | Phase 1 | Withdrawn | Barbara Ann Karmanos Cancer Institute | 2009-06-01 | 2013-04-16 | |
| Ursodiol, Combination Chemotherapy, and Bevacizumab in Treating Patients With Stage IV Colorectal Cancer bevacizumab, FOLFOX regimen, fluorouracil - Colorectal Cancer | Phase 1 | Completed | City of Hope Medical Center | 11 | 2009-03-11 | 2025-06-22 |
| Sunitinib Before and After Surgery in Treating Patients With Metastatic Kidney Cancer That Can Be Removed By Surgery sunitinib malate, gene expression analysis, reverse transcriptase-polymerase chain reaction - Kidney Cancer | Phase 1 | Terminated | Harry Drabkin | 17 | 2008-10-01 | 2015-10-22 |
| PTC299 in Treating Patients With HIV-Related Kaposi Sarcoma VEGF inhibitor PTC299, gene expression analysis, polymerase chain reaction - Kaposi's Sarcoma | Phase 1 / Phase 2 | Terminated | AIDS Malignancy Consortium | 17 | 2008-09-01 | 2018-06-06 |
| Dasatinib and Vorinostat in Treating Patients With Accelerated Phase or Blastic Phase Chronic Myelogenous Leukemia or Acute Lymphoblastic Leukemia dasatinib, vorinostat, cytogenetic analysis - Leukemia | Phase 1 | Completed | City of Hope Medical Center | 5 | 2008-09-01 | 2012-07-17 |
| Clofarabine and Rituximab in Treating Patients With Relapsed Non-Hodgkin Lymphoma rituximab, clofarabine, DNA methylation analysis - Lymphoma | Phase 1 / Phase 2 | Terminated | OHSU Knight Cancer Institute | 2 | 2008-05-01 | 2019-11-27 |
| PEG-Interferon Alfa-2b and Sorafenib in Treating Patients With Unresectable or Metastatic Kidney Cancer PEG-interferon alfa-2b, Sorafenib, gene expression analysis - Kidney Cancer | Phase 1 | Terminated | Thomas Olencki | 1 | 2008-02-01 | 2015-06-08 |
| Vorinostat, Rituximab, Ifosfamide, Carboplatin, and Etoposide in Treating Patients With Relapsed or Refractory Lymphoma or Previously Untreated T-Cell Non-Hodgkin Lymphoma or Mantle Cell Lymphoma vorinostat, rituximab, ifosfamide - Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma | Phase 1 / Phase 2 | Completed | University of Washington | 29 | 2007-12-01 | 2017-05-25 |
| Genetic Testing in Predicting Biomarkers of Recurrence in Patients With Prostate Cancer Undergoing Surgery DNA analysis, DNA methylation analysis, RNA analysis - Prostate Cancer | Phase 1 | Active not recruiting | City of Hope Medical Center | 1045 | 2007-11-26 | 2026-08-20 |
| Sorafenib and Isolated Limb Infusion of Melphalan in Treating Patients With Stage III Melanoma of the Arm or Leg melphalan, sorafenib tosylate, gene expression analysis - Melanoma (Skin) | Phase 1 | Completed | Duke University | 20 | 2007-10-01 | 2015-03-06 |
| Pertuzumab and Cetuximab in Treating Patients With Previously Treated Locally Advanced or Metastatic Colorectal Cancer pertuzumab, cetuximab, irinotecan hydrochloride - Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 17 | 2007-10-01 | 2015-03-31 |
Showing 20 of 37. Sign in to see all of them.
Precursor Cell Lymphoblastic Leukemia-Lymphoma (5) · Rectal Neoplasms (5) · Central Nervous System Neoplasms (4) · Colonic Neoplasms (4) · Glioblastoma (4) · Gliosarcoma (4) · Carcinoma, Renal Cell (3) · Colorectal Neoplasms (3) · Kidney Neoplasms (3) · Leukemia, Lymphocytic, Chronic, B-Cell (3) · Melanoma (3) · Anemia, Refractory, with Excess of Blasts (2) · Brain Neoplasms (2) · Breast Neoplasms (2) · Burkitt Lymphoma (2)
City of Hope Medical Center (7) · Case Comprehensive Cancer Center (2) · Mayo Clinic (2) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (2) · University of California, Davis (2) · University of California, San Francisco (2) · AIDS Malignancy Consortium (1) · Barbara Ann Karmanos Cancer Institute (1) · Cancer Research UK (1) · Cytheris SA (1) · Duke University (1) · Fred Hutchinson Cancer Center (1) · Gustave Roussy, Cancer Campus, Grand Paris (1) · Harry Drabkin (1) · Institute of Head and Neck Studies and Education, United Kingdom (1)
United States (28) · United Kingdom (2) · France (1)
Allen E. Bale, MD (1) · Angela Davies, MD (1) · Anthony Chalmers, Prof (1) · Anthony Stein, MD (1) · Arthur Blackstock (1) · Asher Chanan-Khan (1) · Bhaumik B. Patel, MD (1) · Brenda Cooper, MD (1) · Caroline Robert, MD (1) · Craig Okada, MD, PhD (1) · David G. Pfister, MD (1) · David Snyder, MD (1) · Douglas S. Tyler, MD (1) · Ehsan Malek, MD (1) · Elizabeth C. Dees, MD (1)
PMID 18090584, PMID 24711549, PMID 25621498, PMID 26903311, PMID 28684537
P30CA033572 (6), U01CA062475 (2), P01CA018029 (1), P30CA016086 (1), P30CA069533 (1), P30CA093373 (1), R01CA102521 (1), U01CA062490 (1), U01CA121947 (1)