Assessment of Serum Concentration of Interleukin-17 and Osteoprotegerin in Response to Surgical Trauma Induced by Management of Mandibular Fractures Via Intraoral Versus Extraoral Approaches: Prospective Cohort Study

NCT06349135 — Unknown, 2 participants, Aya Ayman Ahmed
ClinicalTrials Daily  ·  Areas  ·  Conditions  ·  Drugs  ·  Sponsors  ·  
RegistryNCT06349135
StatusUnknown
Study typeObservational
Enrollment2 (Estimated)
SponsorAya Ayman Ahmed (Other)
ConditionsMandibular Fractures
InterventionsOpen Reduction & Internal Fixation (Procedure)
Datesstart 2024-04-15 (estimated), primary completion 2024-04-15 (estimated), completion 2025-12-15 (estimated), first posted 2024-04-05, last updated 2024-04-05

Related Papers Related Patents Related Grants Related Experts
All trials for Mandibular Fractures All trials of Open Reduction & Internal Fixation

-Summary

Assessment of Serum Concentration of Interleukin-17 and Osteoprotegerin in Response to Surgical Trauma Induced by Management of Mandibular Fractures via Intraoral Versus Extraoral Approaches: Prospective Cohort Study

Expand all sections  ·  Collapse all

+Arms and interventions

ArmTypeInterventionsDescription
Management of Mandibular Fractures via Intraoral approach.Procedure: Open Reduction & Internal FixationManagement of Mandibular Fractures via Intraoral approach.
Management of Mandibular Fractures via Extraoral approach.Procedure: Open Reduction & Internal FixationManagement of Mandibular Fractures via Extraoral approach.
  • Open Reduction & Internal Fixation (Procedure): Open Reduction \& Internal Fixation of Mandibular fracture either through intraoral or extraoral approaches.

+Outcome measures

Primary outcomes

  • IL-17 [6- weeks]: Interleukin-17
  • OPG [6- weeks]: Osteoprotegerin

Secondary outcomes

  • Blood Loss [in operation room]
  • Operative time [Operative time in minutes]

+Eligibility

Sex: All, ages: 18 Years to 50 Years, accepts healthy volunteers

Inclusion Criteria:

* Single mandibular fracture.
* ORIF is done by two plates fixation with titanium plates and screws.
* Age (18-50 years).
* Recent fracture (less than 2 weeks).

Exclusion Criteria:

* Pathological fractures.
* Medical compromised patient.
* Presence of concomitant injuries.
* Patients receive radiotherapy.
* Patients receive blood transfusion.