4 completed, 3 terminated. 7 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 7 | Completed 4, Terminated 3 |
| Phase 2 | 3 | Terminated 2, Completed 1 |
Follow fosbretabulin: new trials by email Literature Review of fosbretabulin trials Research Report on fosbretabulin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Fosbretabulin With Everolimus in Neuroendocrine Tumors With Progression everolimus, fosbretabulin - Neuroendocrine Tumors, Everolimus | Phase 1 | Terminated | Lowell Anthony, MD | 17 | 2017-03-06 | 2019-08-08 |
| PAZOFOS: Phase Ib and Phase II Trial of Pazopanib +/- Fosbretabulin in Advanced Recurrent Ovarian Cancer Pazopanib, Fosbretabulin - Ovarian Neoplasms, Neoplasms, Ovarian | Phase 1 / Phase 2 | Terminated | The Christie NHS Foundation Trust | 21 | 2014-09-01 | 2021-05-17 |
| Safety Study of Increasing Doses of Combretastatin in Combination With Bevacizumab (Avastin) in Patients With Advanced Solid Tumors Combretastatin A4 Phosphate (CA4P), Bevacizumab (Avastin) - Tumors | Phase 1 | Completed | Mateon Therapeutics | 20 | 2006-09-01 | 2011-10-31 |
| Induction Chemotherapy Using Doxorubicin and Cisplatin Followed by Combretastatin A4 Phosphate and Radiation Therapy in Treating Patients With Newly Diagnosed Regionally Advanced Anaplastic Thyroid Cancer filgrastim, pegfilgrastim, cisplatin - Head and Neck Cancer | Phase 1 / Phase 2 | Terminated | Case Comprehensive Cancer Center | 4 | 2003-11-01 | 2010-06-11 |
| Combretastatin A4 Phosphate in Patients With Neovascular Age-Related Macular Degeneration Combretastatin A-4 phosphate, Combretastatin A-4 Phosphate - Combretastatin A4 Phosphate, Age-related Macular Degeneration | Phase 1 / Phase 2 | Completed | Johns Hopkins University | 8 | 2003-05-01 | 2017-12-06 |
| Combretastatin A4 Phosphate in Treating Patients With Advanced Solid Tumors fosbretabulin disodium - Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | Completed | Case Comprehensive Cancer Center | 25 | 1998-09-01 | 2014-01-07 |
| Chemotherapy in Treating Patients With Solid Tumors fosbretabulin disodium - Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | Completed | University of Glasgow | 35 | 1998-07-01 | 2013-12-19 |
Choroidal Neovascularization (1) · Head and Neck Neoplasms (1) · Macular Degeneration (1) · Neoplasm Metastasis (1) · Neoplasms (1) · Neuroendocrine Tumors (1) · Ovarian Neoplasms (1) · Thyroid Carcinoma, Anaplastic (1)
Case Comprehensive Cancer Center (2) · Johns Hopkins University (1) · Lowell Anthony, MD (1) · Mateon Therapeutics (1) · The Christie NHS Foundation Trust (1) · University of Glasgow (1)
United States (4) · United Kingdom (3)
Gordon J.S. Rustin, MD (1) · Gordon Jayson (1) · Gordon Rustin (1) · Hillori Connors, MS (1) · Lowell Anthony, MD (1) · Panayiotis Savvides, MD (1) · Paul Nathan, MD (1) · Peter Harris, MD (1) · Quan D Nguyen, MD, MSc (1) · Scot C. Remick, MD (1)
PMID 12807934, PMID 23316779, PMID 31932108, PMID 37816266
P30CA043703 (1)