46 completed, 15 unknown, 5 recruiting, 5 terminated. 74 Phase 3, 16 Phase 2.
Follow Folic Acid: new trials by email Literature Review of Folic Acid trials Research Report on Folic Acid
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Micronutrient Enhancement for Development and Health in Adolescents - The MEDHA Study Iron (60 mg)- folic acid (400 ug) [IFA], Multiple micronutrient supplement [MMS], Multiple micronutrient supplement Plus [MMS+] - Neurodevelopment Outcome, Linear Growth | Phase 3 | Recruiting | Johns Hopkins Bloomberg School of Public Health | 3000 | 2026-09-27 | 2026-10-09 |
| Effect of Aspirin and Folic Acid for Sudden Sensorineural Hearing Loss Aspirin + Acid folic, Placebo Aspirin + Placebo Acid folic - Sudden Sensorineural Hearing Loss | Phase 3 | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 142 | 2026-04-01 | 2026-01-14 |
| Efficacy of Alpha Lipoic Acid Combined With Myo-Inositol in Non-Diabetic PCOS Patients Myo-inositol, Folic Acid, Alpha Lipoic Acid - Poly Cystic Ovary Syndrome | Phase 3 | Recruiting | Beni-Suef University | 180 | 2026-03-10 | 2026-06-05 |
| Growth Hormone and Dehydroepiandrosterone Role in Vitro Fertilization Somatropin (4IU for 1 month) plus, folic acid 400 mcg per day., DHEA plus folic acid 400mcg per day, control group - Infertility, Infertility (IVF Patients) | Phase 2 / Phase 3 | Recruiting | Beni-Suef University | 165 | 2025-10-10 | 2026-01-07 |
| Role of Folic Acid in the Management of Adjuvant Endocrine Therapy-Induced Hot Flashes in Breast Cancer Patients Folic Acid 1 Mg Oral Tablet, Folic Acid 5 Mg Oral Tablet - THERAPY-INDUCED HOT FLASHES IN BREAST CANCER PATIENTS | Phase 3 | Completed | Future University in Egypt | 120 | 2025-04-05 | 2026-09-23 |
| of Myo-inositol, Melatonin and Co-enzyme q10 on Ovarian Reserve Myoinositol, Co-Enzyme Q10, Melatonin - IVF | Phase 3 | Unknown | Beni-Suef University | 200 | 2024-06-30 | 2024-05-08 |
| Efficacy and Safety in the Combination of Celecoxib / Pregabalin / Vitamin B for Low Back Chronic Pain Celecoxib+Pregabalin+Vitamin B fixed dose, Celecoxib + Vitamin B fixed dose, Pregabalin + Vitamin B fixed dose - Chronic Low-back Pain | Phase 3 | Completed | Laboratorios Silanes S.A. de C.V. | 192 | 2024-04-11 | 2025-04-04 |
| Safety and Efficacy of Baricitinib on Skin Tightening in Diffuse Cutaneous Systemic Sclerosis: A Comparative Study With Methotrexate tab baricitinib 4 mg daily, tab methotrexate 25 mg weekly with folic acid 5 mg weekly - Diffuse Cutaneous Systemic Sclerosis | Phase 3 | Recruiting | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | 24 | 2024-01-01 | 2025-04-20 |
| Prevention of Iron Deficiency Anemia Post-delivery Ferric carboxymaltose (FCM) and folic acid tablets, Oral iron tablets and folic acid tablets - Postpartum Anemia | Phase 3 | Completed | NICHD Global Network for Women's and Children's Health | 4857 | 2023-05-30 | 2026-07-01 |
| Study of Effects of Preoperative Oral Domperidone on Gastric Residual Volume After Clear Fluid Ingestion in Patients Scheduled for Elective Surgeries Domperidone, Folic acid - Gastric Residual Volume | Phase 3 | Completed | Ain Shams University | 40 | 2022-10-10 | 2023-05-15 |
| Testing the Use of Combination Immunotherapy Treatment (N-803 [ALT-803] Plus Pembrolizumab) Against the Usual Treatment for Advanced Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial) Cobalamin, Dexamethasone, Docetaxel - Advanced Lung Non-Small Cell Carcinoma, Recurrent Lung Non-Small Cell Carcinoma | Phase 2 / Phase 3 | Active not recruiting | SWOG Cancer Research Network | 82 | 2022-03-15 | 2026-05-18 |
| Effect of Folic Acid and/or Pentoxifylline on Patients With Chronic Kidney Disease combination of Pentoxifylline 400 MG and Folic Acid, folic acid, Pentoxifylline 400 MG - Chronic Kidney Diseases | Phase 3 | Active not recruiting | Al-Azhar University | 80 | 2022-01-08 | 2025-06-11 |
| Study of Pemetrexed+Platinum Chemotherapy With or Without Cosibelimab in First Line Metastatic Non-squamous NSCLC Cosibelimab, Cisplatin, Carboplatin - Metastatic Non-squamous Non Small Cell Lung Cancer | Phase 3 | Terminated | Checkpoint Therapeutics, Inc. | 25 | 2021-12-08 | 2025-04-02 |
| InDuctIon TREatment with SubCuTaneous Infliximab for Crohn's Disease Infliximab subcutaneous, Immunosuppressive Agents - Inflammatory Disease, Disease Crohn | Phase 3 | Recruiting | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 158 | 2021-11-25 | 2024-12-10 |
| Efficacy and Safety of Dexketoprofen/Vitamin B Vs Dexketoprofen for Post-traumatic Cervical Sprain Grade I-II Dexketoprofen/Vitamin B, Dexketoprofen - Acute Low Back Pain | Phase 3 | Completed | Laboratorios Silanes S.A. de C.V. | 174 | 2021-11-23 | 2024-11-13 |
| Managing Endothelial Dysfunction in Critically Ill COVID-19 Patients at LAUMCRH Endothelial Protocol - Covid19, Endothelial Dysfunction | Phase 3 | Unknown | Lebanese American University Medical Center | 70 | 2021-01-20 | 2021-03-24 |
| Managing Endothelial Dysfunction in COVID-19 : A Randomized Controlled Trial at LAUMC Atorvastatin + L-arginine + Folic acid + Nicorandil + Nebivolol, Placebo - Covid19 | Phase 3 | Unknown | Lebanese American University Medical Center | 42 | 2021-01-10 | 2022-02-14 |
| School-Based Assessment of Micronutrient Interventions in Adolescents in Burkina Faso Iron and folic acid (IFA), Multiple Micronutrient Supplements (MMS) and loading dose of Iron and Folic Acid (IFA) - Anemia | Phase 3 | Completed | Harvard School of Public Health (HSPH) | 3123 | 2020-12-11 | 2024-05-22 |
| Low Dose Prednisone Therapy in Women With Recurrent Pregnancy Loss Prednisone, Progesterone, vit D - Recurrent Pregnancy Loss(RPL), Recurrent Miscarriage | Phase 2 / Phase 3 | Unknown | Soroka University Medical Center | 242 | 2020-12-01 | 2020-09-22 |
| Intravenous Versus Oral Iron Therapy in Hemodialysis Patients Intravenous iron, Oral iron - Hemodialysis Complication, Anemia | Phase 3 | Unknown | Chiang Mai University | 124 | 2020-07-29 | 2020-08-11 |
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Arthritis, Rheumatoid (11) · Carcinoma, Non-Small-Cell Lung (5) · Anemia (4) · Colorectal Neoplasms (4) · COVID-19 (3) · Malnutrition (3) · Abortion, Habitual (2) · Anemia, Iron-Deficiency (2) · Cardiovascular Diseases (2) · Cleft Lip (2) · Cleft Palate (2) · Congenital Abnormalities (2) · Lung Neoplasms (2) · Myocardial Infarction (2) · Perinatal Death (2)
Beni-Suef University (3) · Genentech, Inc. (3) · Ain Shams University (2) · Assistance Publique - Hôpitaux de Paris (2) · Johns Hopkins Bloomberg School of Public Health (2) · Laboratorios Silanes S.A. de C.V. (2) · Lebanese American University Medical Center (2) · Merck Sharp & Dohme LLC (2) · NICHD Global Network for Women's and Children's Health (2) · National Institute on Aging (NIA) (2) · Sanofi (2) · AIO-Studien-gGmbH (1) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Al-Azhar University (1) · All India Institute of Medical Sciences (1)
United States (12) · Egypt (9) · Brazil (8) · Canada (8) · India (8) · Germany (7) · Argentina (6) · Mexico (6) · China (5) · Russia (5) · Australia (4) · Bangladesh (4) · France (4) · Greece (4) · Italy (4)
Adelfia Urenda Quezada, M.D (1) · Adelfia Urenda-Quezada (1) · Ahmadreza Jamshidi, Professor (1) · Alex Palatnik, MD (1) · Aline G. Ferrari, MD (1) · Anshu Vashishtha, MD PhD (1) · Arndt Schottelius, M.D. (1) · Brian Greenwood, MD (1) · Christine Johnston, MD, MPH (1)
PMID 37465924, PMID 38642841, PMID 11001674, PMID 11844814, PMID 12324494, PMID 12507972, PMID 12621133, PMID 14699020, PMID 15321804, PMID 15910853, PMID 16543037, PMID 16613998, PMID 16849761, PMID 17551129, PMID 17645592, PMID 18510727, PMID 18620104, PMID 18714059, PMID 18854539, PMID 19118243, PMID 19125808, PMID 19549699, PMID 19687335, PMID 19923375, PMID 20484456, PMID 20488885, PMID 20494665, PMID 20937671, PMID 21083513, PMID 21270268, PMID 21310866, PMID 21482950, PMID 21557525, PMID 22012969, PMID 22127691, PMID 22231424, PMID 22336956, PMID 23181832, PMID 23303315, PMID 23669628, PMID 23734218, PMID 23835707, PMID 23936148, PMID 24055428, PMID 24103380, PMID 24297381, PMID 24349782, PMID 24647388, PMID 24884885, PMID 24885137
2008 (2), 2009 (1), 2015 (1), M01RR000052 (1), R01AG017160 (1), U01DE017958 (1), U01HL050981 (1), U10CA180888 (1)