46 completed, 5 unknown, 5 withdrawn, 3 terminated. 25 Phase 2, 9 Phase 1, 4 Phase 3, 2 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 25 | Completed 19, Terminated 3, Withdrawn 2, Unknown 1 |
| Phase 1 | 9 | Completed 7, Withdrawn 2 |
| Phase 3 | 4 | Completed 3, Unknown 1 |
| Not applicable | 2 | Completed 1, Unknown 1 |
Follow fluorescence in situ hybridization: new trials by email Literature Review of fluorescence in situ hybridization trials Research Report on fluorescence in situ hybridization
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Studying Biomarkers in Samples From Young Patients With Rhabdoid Tumors DNA analysis, fluorescence in situ hybridization, gene expression analysis - Kidney Cancer | Completed | Children's Oncology Group | 50 | 2012-03-01 | 2016-05-18 | |
| Biomarkers in Tumor Samples From Younger Patients With Neuroblastoma fluorescence in situ hybridization, gene expression analysis, microarray analysis - Neuroblastoma | Completed | Children's Oncology Group | 5 | 2011-12-01 | 2016-07-11 | |
| Cancer Stem Cell Biomarkers as a Predictor of Response to Trastuzumab in Samples From Patients With Breast Cancer Previously Treated in the NSABP-B-31 Trial fluorescence in situ hybridization, immunohistochemistry staining method, immunologic technique - Breast Cancer | Unknown | NSABP Foundation Inc | 1874 | 2011-11-01 | 2015-05-08 | |
| Biomarkers in Patients With Rhabdomyosarcoma DNA methylation analysis, fluorescence in situ hybridization, gene expression analysis - Sarcoma | Completed | Children's Oncology Group | 20 | 2011-10-01 | 2016-05-19 | |
| Docetaxel and Lapatinib in Metastatic Transitional Cell Carcinoma in Bladder docetaxel, lapatinib ditosylate, immunohistochemistry staining method - Recurrent Bladder Cancer, Stage III Bladder Cancer | Phase 2 | Terminated | University of Southern California | 15 | 2011-06-13 | 2025-10-09 |
| Biomarkers in Blood and Bone Marrow Samples From Patients With Acute Lymphoblastic Leukemia DNA analysis, fluorescence in situ hybridization, gene expression analysis - Leukemia | Completed | Alliance for Clinical Trials in Oncology | 200 | 2011-02-01 | 2020-02-20 | |
| Everolimus and Lenalidomide in Treating Patients With Relapsed or Refractory Non-Hodgkin or Hodgkin Lymphoma everolimus, lenalidomide, laboratory biomarker analysis - Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma | Phase 1 / Phase 2 | Completed | Mayo Clinic | 58 | 2011-01-10 | 2020-10-22 |
| Imprime PGG, Alemtuzumab, and Rituximab in Treating Patients With High Risk Chronic Lymphocytic Leukemia alemtuzumab, rituximab, PGG beta-glucan - B-cell Chronic Lymphocytic Leukemia, Refractory Chronic Lymphocytic Leukemia | Phase 1 / Phase 2 | Completed | Mayo Clinic | 22 | 2011-01-01 | 2020-06-23 |
| Azadirachta Indica in Treating Patients With Chronic Lymphocytic Leukemia laboratory biomarker analysis, western blotting, gene expression analysis - Refractory Chronic Lymphocytic Leukemia, Stage II Chronic Lymphocytic Leukemia | Phase 1 | Withdrawn | Roswell Park Cancer Institute | 2010-12-01 | 2014-01-13 | |
| Biomarkers of Response in Blood and Tumor Tissue Samples From Patients With Unresectable Stage IV Squamous Cell Cancer of the Head and Neck Previously Treated With Cetuximab, Cisplatin, and Radiation Therapy fluorescence in situ hybridization, gene expression analysis, polymerase chain reaction - Head and Neck Cancer | Completed | ECOG-ACRIN Cancer Research Group | 69 | 2010-08-05 | 2017-05-17 | |
| Studying Genes in Samples From Younger Patients With Acute Lymphoblastic Leukemia DNA analysis, fluorescence in situ hybridization, gene expression analysis - Leukemia | Unknown | Eastern Cooperative Oncology Group | 400 | 2010-08-01 | 2013-07-10 | |
| DNA Biomarkers in Samples From Patients With Osteosarcoma and Healthy Volunteers DNA analysis, RNA analysis, fluorescence in situ hybridization - Sarcoma | Completed | Children's Oncology Group | 90 | 2010-04-01 | 2016-05-18 | |
| Study of Biomarkers in Blood and Bone Marrow Samples From Patients With Previously Untreated Chronic Lymphocytic Leukemia fluorescence in situ hybridization, mutation analysis, nucleic acid sequencing - Leukemia | Completed | Alliance for Clinical Trials in Oncology | 600 | 2009-10-01 | 2022-08-03 | |
| Study of Tumor Tissue Testing in Selecting Treatment for Patients With Metastatic or Locally Advanced Colorectal Cancer bevacizumab, cetuximab, fluorouracil - Colorectal Cancer | Phase 2 / Phase 3 | Completed | Medical Research Council | 3240 | 2009-07-01 | 2013-12-19 |
| Study of Tumor Samples in Patients Undergoing Radiation Therapy or Surgery For Primary Melanoma of the Eye fluorescence in situ hybridization, laboratory biomarker analysis, fine-needle aspiration - Intraocular Melanoma | Completed | Case Comprehensive Cancer Center | 150 | 2009-03-01 | 2015-01-30 | |
| Nilotinib and Imatinib Mesylate in Treating Patients With Early Chronic Phase Chronic Myelogenous Leukemia imatinib mesylate, nilotinib, cytogenetic analysis - Leukemia | Phase 2 | Completed | Gruppo Italiano Malattie EMatologiche dell'Adulto | 129 | 2009-02-09 | 2022-01-04 |
| Fludarabine Phosphate, Rituximab, and Bevacizumab in Treating Patients With B-Cell Chronic Lymphocytic Leukemia That Has Relapsed or Not Responded To Treatment fludarabine phosphate, rituximab, bevacizumab - B-cell Chronic Lymphocytic Leukemia, Refractory Chronic Lymphocytic Leukemia | Phase 2 | Withdrawn | Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium | 2009-01-01 | 2015-03-06 | |
| Donor Stem Cell Transplant, Pentostatin, and Total-Body Irradiation in Treating Patients With Hematological Cancer cyclosporine, mycophenolate mofetil, pentostatin - Chronic Myeloproliferative Disorders, Leukemia | Phase 1 / Phase 2 | Withdrawn | University of Nebraska | 2008-09-01 | 2023-08-14 | |
| CLL-Irl Study. CTRIAL-IE (ICORG) 07-01, V7 pegfilgrastim, rituximab, cyclophosphamide - Leukemia | Phase 2 | Completed | Cancer Trials Ireland | 52 | 2008-08-18 | 2025-07-08 |
| Laboratory Study Using Samples From Patients With Non-Small Cell Lung Cancer Treated on Clinical Trial CASE-2507 DNA analysis, RNA analysis, fluorescence in situ hybridization - Lung Cancer | Withdrawn | Case Comprehensive Cancer Center | 2008-08-01 | 2014-07-24 |
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Leukemia (12) · Leukemia, Lymphocytic, Chronic, B-Cell (12) · Breast Neoplasms (10) · Congenital Abnormalities (9) · Leukemia, Myeloid, Acute (7) · Lymphoma, Mantle-Cell (7) · Lymphoma, B-Cell, Marginal Zone (6) · Lymphoma, Follicular (6) · Multiple Myeloma (6) · Myeloproliferative Disorders (6) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (6) · Burkitt Lymphoma (5) · Carcinoma, Non-Small-Cell Lung (5) · Colonic Neoplasms (5) · Leukemia, Myeloid, Chronic-Phase (5)
Case Comprehensive Cancer Center (7) · Alliance for Clinical Trials in Oncology (6) · Children's Oncology Group (5) · City of Hope Medical Center (3) · European Organisation for Research and Treatment of Cancer - EORTC (3) · Fred Hutchinson Cancer Center (3) · ECOG-ACRIN Cancer Research Group (2) · Mayo Clinic (2) · Memorial Sloan Kettering Cancer Center (2) · SWOG Cancer Research Network (2) · Vanderbilt-Ingram Cancer Center (2) · Barbara Ann Karmanos Cancer Institute (1) · Cancer Trials Ireland (1) · Children's Cancer and Leukaemia Group (1) · Dr. Susan Love Research Foundation (1)
United States (34) · France (3) · United Kingdom (3) · Belgium (2) · Ireland (2) · Italy (2) · Australia (1) · Canada (1) · Germany (1) · Switzerland (1)
Afshin Dowlati, MD (1) · Ahmad Awada, MD, PhD (1) · Andrew D. Zelenetz, MD, PhD (1) · Anthony Michalski, MD (1) · Ari M. Melnick, MD (1) · Arun D. Singh, MD (1) · Asher Chanan-Khan (1) · B. Douglas Smith, MD (1) · Balazs Halmos, MD (1) · Bart Scott (1) · Brenda Cooper, MD (1) · Caroline Y. Hu, MD (1) · Charles Mullighan, MD (1) · Craig Reeder, M.D. (1) · Daniel F. Hayes, MD (1)
PMID 21321091, PMID 22989664, PMID 23041588, PMID 24831979, PMID 25361995, PMID 28925785
P30CA043703 (5), U10CA031946 (2), U10CA032102 (2), 2008 (1), K23HL084054 (1), P01CA018029 (1), P01CA078902 (1), P01HL036444 (1), P30CA006973 (1), P30CA008748 (1), P30CA014236 (1), P30CA022453 (1), P30CA033572 (1), P30CA036727 (1), P30CA046592 (1)