6 completed, 4 terminated, 2 unknown, 1 not yet recruiting. 4 Phase 3, 4 Phase 4, 3 Phase 2, 2 Not applicable, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 4 | Completed 3, Not yet recruiting 1 |
| Phase 4 | 4 | Terminated 2, Unknown 1, Withdrawn 1 |
| Phase 2 | 3 | Completed 2, Terminated 1 |
| Not applicable | 2 | Completed 1, Terminated 1 |
| Phase 1 | 1 | Terminated 1 |
Follow ferryl iron: new trials by email Literature Review of ferryl iron trials Research Report on ferryl iron
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Impact of IV Iron on Bleeding Symptoms in Iron Deficient Patients With Inherited Bleeding Disorders IV Iron (standard of care) - Bleeding Disorders, Iron | Recruiting | Nicoletta C Machin | 40 | 2025-08-08 | 2026-10-06 | |
| IRONICA: IRON Repletion In Heart Failure - A Comparison of Oral and IV Approaches Ferric Carboxymaltose, Ferrous Sulfate - Heart Failure, Heart Failure With Reduced Ejection Fraction (HFrEF) | Phase 4 | Terminated | Syed Hamza Mufarrih | 42 | 2025-04-02 | 2026-07-20 |
| Effect of Intravenously Iron Infusion on the Prevention and Treatment of Anemia in Ovarian Cancer IV iron - Anaemia in Ovarian Carcinoma | Phase 3 | Not yet recruiting | University of Saskatchewan | 200 | 2024-02-29 | 2024-02-08 |
| Erythropoietin And/Or Iron Sucrose For Perioperative Anemia Management In Hip and Knee Arthroplasty rHuEPO, Iron sucrose - Anemia, Iron Deficiency | Unknown | Peking Union Medical College Hospital | 780 | 2019-04-24 | 2019-04-25 | |
| Artificial Intelligence for Optimal Anemia Management in End-stage Renal Disease: The Anemia Control Model (ACM) Trial Anemia Control Model (ACM), IV iron, Erythropoiesis-Stimulating Agent (ESA) - Anemia, End Stage Renal Disease | Not applicable | Terminated | Vifor Fresenius Medical Care Renal Pharma | 88 | 2018-12-10 | 2020-01-07 |
| Preoperative Intravenous Iron Infusion to Reduce Post-surgical Complications: a Pilot Randomised Control Trial Ferric carboxymaltose, Ferrous Fumarate - Anemia, Major Abdominal Surgery | Phase 4 | Unknown | Singapore General Hospital | 60 | 2017-11-22 | 2018-12-05 |
| HepciFer Study: Hepcidin Overexpression After Hepatectomy : Does Iron Supplementation Make Sense ? IV iron, IV placebo - Anemia, Postoperative Blood Loss | Phase 3 | Completed | University Hospital, Geneva | 50 | 2015-10-01 | 2017-05-05 |
| A Phase 3b Study of Erythropoietin Drugs Using a Specified Dosing Algorithm in Patients With Chronic Kidney Disease on Hemodialysis Epoetin Hospira Arm, Standard of Care Arm, IV Iron - Chronic Kidney Disease (CKD) | Phase 3 | Completed | Pfizer | 432 | 2015-07-13 | 2018-06-13 |
| A Randomized Study to Compare the Dosing Schedule of INFeD in Anemic Patients. IV iron - Anemia, Iron Deficiency | Phase 4 | Withdrawn | Sutter Gould Medical Foundation | 2015-04-14 | 2019-06-05 | |
| Pilot Study: Randomized, Placebo-controlled Comparator Trial of IV vs Oral Iron Treatment of RLS With IDA. (IVOR-IDA) Ferumoxytol intravenous, Ferrous sulfate - Restless Legs Syndrome, Iron Deficiency Anemia | Phase 2 | Completed | Auerbach Hematology Oncology Associates P C | 100 | 2014-08-01 | 2024-01-30 |
| The Effect of Pomegranate Juice (PJ) on Oxidative Stress Biomarkers During Treatment With IV Iron During One Dialysis Session PJ, IV iron - Cardiovascular Disease (CVD) | Not applicable | Completed | Western Galilee Hospital-Nahariya | 25 | 2014-04-01 | 2016-02-09 |
| Active Preoperative Anemia Management in Patients Undergoing Cardiac Surgery EPO, Feraheme - Anemia, Cardiovascular Disease | Phase 1 / Phase 2 | Terminated | University of Texas Southwestern Medical Center | 5 | 2013-04-09 | 2020-10-23 |
| Study of Roxadustat (FG-4592) to Correct Anemia in Newly Initiated Dialysis Participants Not on Erythropoiesis-Stimulating Agent Treatment Roxadustat, Oral Iron, IV Iron - Dialysis, Anemia | Phase 2 | Completed | Kyntra Bio | 60 | 2011-07-21 | 2021-10-01 |
| Efficacy and Safety of Intravenous Ferric Carboxymaltose (FCM) in Patients With Iron Deficiency Anemia (IDA) Ferric Carboxymaltose (FCM), Ferrous Sulfate Tablets, IV Iron (standard of care) - Iron Deficiency Anemia | Phase 3 | Completed | American Regent, Inc. | 997 | 2009-09-01 | 2018-02-20 |
| A Clinical Trial of Oral Versus IV Iron in Patients With Chronic Kidney Disease IV Iron, Ferrous Sulfate - Chronic Kidney Disease, Iron-deficiency Anemia | Phase 4 | Terminated | Indiana University | 136 | 2008-08-01 | 2016-07-21 |
Anemia, Iron-Deficiency (7) · Anemia (6) · Cardiovascular Diseases (2) · Iron Deficiencies (2) · Kidney Failure, Chronic (2) · Renal Insufficiency, Chronic (2) · Disease Progression (1) · Heart Failure (1) · Hemorrhage (1) · Hemostatic Disorders (1) · Kidney Diseases (1) · Postoperative Hemorrhage (1) · Restless Legs Syndrome (1)
American Regent, Inc. (1) · Auerbach Hematology Oncology Associates P C (1) · Indiana University (1) · Kyntra Bio (1) · Nicoletta C Machin (1) · Peking Union Medical College Hospital (1) · Pfizer (1) · Singapore General Hospital (1) · Sutter Gould Medical Foundation (1) · Syed Hamza Mufarrih (1) · University Hospital, Geneva (1) · University of Saskatchewan (1) · University of Texas Southwestern Medical Center (1) · Vifor Fresenius Medical Care Renal Pharma (1) · Western Galilee Hospital-Nahariya (1)
United States (9) · Singapore (2) · Canada (1) · China (1) · Hong Kong (1) · Israel (1) · Puerto Rico (1) · Russia (1) · Switzerland (1) · United Kingdom (1)
Batya Kristal, MD (1) · David Adkins, MD (1) · Eduardo Schiffer, MD (1) · Hairil Rizal Abdullah (1) · Iain Macdougall (1) · Maryam Al-Hayki (1) · Michael Auerbach, MD (1) · Nicoletta Machin, DO (1) · Philip E. Greilich, MD (1) · Rajiv Agarwal, MD FASN FAHA (1) · Wei Wang, PhD (1)
PMID 30051186, PMID 30196301, PMID 30853478, PMID 32331365, PMID 35363499, PMID 35956390, PMID 36005278, PMID 36791280, PMID 39185895, PMID 39443013
U01DK071633 (1)