7 completed, 3 terminated, 1 suspended, 1 unknown. 7 Phase 1, 7 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 7 | Completed 4, Terminated 2, Suspended 1 |
| Phase 2 | 7 | Completed 4, Terminated 2, Unknown 1 |
| Phase 3 | 1 | Completed 1 |
Follow eniluracil: new trials by email Literature Review of eniluracil trials Research Report on eniluracil
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase 2 Study of PCS6422 With Capecitabine in Patients With Advanced or Metastatic Breast Cancer PCS6422 and capecitabine, Capecitabine - Breast Cancer, TNBC - Triple-Negative Breast Cancer | Phase 2 | Terminated | Processa Pharmaceuticals | 20 | 2024-10-02 | 2026-10-06 |
| Study of Eniluracil + 5-Fluorouracil (5-FU) + Leucovorin Versus Capecitabine in Metastatic Breast Cancer Eniluracil, 5-Fluorouracil, Leucovorin - Metastatic Breast Cancer | Phase 2 | Unknown | Adherex Technologies, Inc. | 140 | 2011-04-01 | 2012-07-17 |
| Eniluracil Hand Foot Syndrome Eniluracil - Breast Cancer, Colon Cancer | Phase 1 | Terminated | West Virginia University | 3 | 2009-01-01 | 2018-05-30 |
| A Study of 5 Fluorouracil and the Anti-Tumor Activity of ADH300004 and 5 Fluorouracil in Subjects With Incurable Solid Tumors ADH300004 - Neoplasms | Phase 1 | Suspended | Adherex Technologies, Inc. | 60 | 2006-01-01 | 2008-12-15 |
| Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Advanced Mouth Cancer ethynyluracil, fluorouracil, hydroxyurea - Head and Neck Cancer | Phase 1 / Phase 2 | Completed | Robert H. Lurie Cancer Center | 1999-10-01 | 2013-06-26 | |
| Eniluracil, Fluorouracil, and Oxaliplatin in Treating Patients With Advanced Colorectal Cancer ethynyluracil, fluorouracil, oxaliplatin - Colorectal Cancer | Phase 1 / Phase 2 | Completed | NYU Langone Health | 1999-08-01 | 2011-03-28 | |
| Fluorouracil With or Without Eniluracil in Treating Patients With Advanced Colorectal Cancer fluorouracil, eniluracil - Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum | Phase 3 | Completed | National Cancer Institute (NCI) | 950 | 1999-04-01 | 2013-01-24 |
| Eniluracil and Surgery in Treating Patients With Primary or Metastatic Colorectal Cancer eniluracil, conventional colon surgery - Colorectal Cancer | Phase 2 | Completed | University of Alabama at Birmingham | 28 | 1998-09-01 | 2015-06-15 |
| SWOG-S9635 Fluorouracil Plus Ethynyluracil in Advanced Colorectal Cancer Not Responded to Fluorouracil ethynyluracil, fluorouracil - Colorectal Cancer | Phase 2 | Completed | SWOG Cancer Research Network | 75 | 1998-04-01 | 2012-03-08 |
| A Phase I Trial of 5-Fluorouracil Given With 776C85 (GW776) and Low-Dose Leucovorin in Adult Patients With Solid Tumors 5-Fluorouracil, Ethynyluracil, Leucovorin - Lymphoma, Neoplasms | Phase 1 | Completed | National Cancer Institute (NCI) | 50 | 1997-06-01 | 2006-07-17 |
| A Study of ADH300004 and 5-Fluorouracil in Locally Advanced, Recurrent, or Metastatic Hepatocellular Carcinoma ADH300004 - Hepatocellular Carcinoma | Phase 1 / Phase 2 | Terminated | Adherex Technologies, Inc. | 2008-12-15 | ||
| A Study of ADH300004 in Surgically Resected Primary or Metastatic Colorectal Cancer and Liver Biopsy, or Planned Hepatic Resection ADH300004 - Neoplasms | Phase 1 | Completed | Adherex Technologies, Inc. | 2007-08-06 |
Colonic Neoplasms (5) · Colorectal Neoplasms (4) · Neoplasms (4) · Rectal Neoplasms (4) · Breast Neoplasms (3) · Carcinoma, Hepatocellular (1) · Head and Neck Neoplasms (1) · Hypopharyngeal Neoplasms (1) · Liver Neoplasms (1) · Lymphoma (1) · Squamous Cell Carcinoma of Head and Neck (1) · Triple Negative Breast Neoplasms (1)
Adherex Technologies, Inc. (4) · National Cancer Institute (NCI) (2) · NYU Langone Health (1) · Processa Pharmaceuticals (1) · Robert H. Lurie Cancer Center (1) · SWOG Cancer Research Network (1) · University of Alabama at Birmingham (1) · West Virginia University (1)
United States (11) · Russia (1) · Singapore (1) · Taiwan (1)
Cynthia G. Leichman, MD (1) · Everett E. Vokes, MD (1) · Howard Burris, III, MD (1) · Howard S. Hochster, MD (1) · Jacqueline Whang-Peng, MD (1) · John Hines (1) · Martin Heslin, MD (1) · Martin J. Heslin, MD (1) · Mridula George, MD (1) · William P. Petros, Pharm D (1)
P30CA016087 (1), U10CA021115 (1), U10CA032102 (1)