6 completed, 2 terminated, 1 suspended, 1 unknown. 8 Phase 1, 6 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 8 | Completed 5, Terminated 2, Suspended 1 |
| Phase 2 | 6 | Completed 3, Terminated 2, Unknown 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| ADH-1, Gemcitabine Hydrochloride & Cisplatin in Treating Metastatic Pancreatic or Biliary Tract Cancer ADH-1, Cisplatin, Gemcitabine Hydrochloride - Ampulla of Vater Adenocarcinoma, Gallbladder Adenocarcinoma | Phase 1 | Completed | University of Nebraska | 17 | 2013-04-09 | 2023-12-28 |
| Study of Eniluracil + 5-Fluorouracil (5-FU) + Leucovorin Versus Capecitabine in Metastatic Breast Cancer Eniluracil, 5-Fluorouracil, Leucovorin - Metastatic Breast Cancer | Phase 2 | Unknown | Adherex Technologies, Inc. | 140 | 2011-04-01 | 2012-07-17 |
| A Study of ADH-1 in Combination With Normothermic Isolated Limb Infusion of Melphalan ADH-1, melphalan - Neoplasms | Phase 1 / Phase 2 | Completed | Adherex Technologies, Inc. | 56 | 2007-04-01 | 2010-12-28 |
| A Study of ADH 1 in Combination With Carboplatin, or Docetaxel or Capecitabine ADH -1 and carboplatin, ADH -1 and docetaxel, ADH -1 and capecitabine - Neoplasms | Phase 1 | Completed | Adherex Technologies, Inc. | 2006-11-01 | 2010-12-28 | |
| A Study of 5 Fluorouracil and the Anti-Tumor Activity of ADH300004 and 5 Fluorouracil in Subjects With Incurable Solid Tumors ADH300004 - Neoplasms | Phase 1 | Suspended | Adherex Technologies, Inc. | 60 | 2006-01-01 | 2008-12-15 |
| Study of ADH-1 Given Intravenously to Patients With Solid Tumors ADH -1 (Exherin™) - Neoplasms | Phase 1 / Phase 2 | Completed | Adherex Technologies, Inc. | 2005-06-01 | 2010-12-28 | |
| A Study of ADH300004 and 5-Fluorouracil in Locally Advanced, Recurrent, or Metastatic Hepatocellular Carcinoma ADH300004 - Hepatocellular Carcinoma | Phase 1 / Phase 2 | Terminated | Adherex Technologies, Inc. | 2008-12-15 | ||
| A Study of the Safety and Effects of ADH-1 Given Daily to Subjects With Solid Tumors ADH -1 (Exherin™) - Neoplasms | Phase 1 / Phase 2 | Terminated | Adherex Technologies, Inc. | 2007-08-06 | ||
| A Study of ADH300004 in Surgically Resected Primary or Metastatic Colorectal Cancer and Liver Biopsy, or Planned Hepatic Resection ADH300004 - Neoplasms | Phase 1 | Completed | Adherex Technologies, Inc. | 2007-08-06 | ||
| A Study of the Safety and Effects of ADH-1 Given Intravenously as a Single Agent ADH -1 (Exherin™) - Neoplasms | Phase 2 | Completed | Adherex Technologies, Inc. | 2007-08-06 |
Neoplasms (8) · Carcinoma, Hepatocellular (2) · Carcinoma, Non-Small-Cell Lung (2) · Adrenocortical Carcinoma (1) · Breast Neoplasms (1) · Carcinoma, Renal Cell (1) · Cholangiocarcinoma (1) · Colorectal Neoplasms (1) · Esophageal Neoplasms (1) · Gallbladder Neoplasms (1) · Klatskin Tumor (1) · Liver Neoplasms (1) · Melanoma (1) · Ovarian Neoplasms (1) · Pancreatic Neoplasms (1)
N-Ac-CHAVC-NH2 (4) · eniluracil (4) · Capecitabine (2) · 1,2-diaminocyclohexaneplatinum II citrate (1) · Carboplatin (1) · Cisplatin (1) · Docetaxel (1) · Fluorouracil (1) · Gemcitabine (1) · Leucovorin (1) · Melphalan (1) · Platinum (1)
United States (9) · Canada (1) · Italy (1) · Russia (1) · Singapore (1) · Switzerland (1) · Taiwan (1)
Doug Tyler, MD (1) · Howard Burris, III, MD (1) · Jacqueline Whang-Peng, MD (1) · Jean L Grem, MD (1) · Martin Heslin, MD (1)
P30CA036727 (1), P50CA127297 (1)