9 completed, 1 active not recruiting. 5 Not applicable, 3 Phase 3, 2 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Completed 4, Active not recruiting 1 |
| Phase 3 | 3 | Completed 3 |
| Phase 2 | 2 | Completed 2 |
| Phase 4 | 1 | Completed 1 |
Follow EDTA: new trials by email Literature Review of EDTA trials Research Report on EDTA
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Different Irrigation Protocols on Postoperative Endodontic Pain and Inflammation EDTA, Etidronate, clodronate - Irrigation Solution, Postoperative Pain | Not applicable | Active not recruiting | Suez Canal University | 75 | 2023-08-20 | 2025-08-11 |
| EDTA Eye Drops Compared to Abreva for Herpes Simplex Virus Eruptions EDTA, Abreva - Herpes Simplex Oral | Phase 2 | Completed | University of Utah | 10 | 2022-01-20 | 2025-10-31 |
| Comparing Different Single and Combination Chelating Agents on Sealer Penetration and Dentin Erosion. Ethylene Diamine Tetra Acetic acid, smearOFF, Etidronic acid /sodium hypochlorite - Root Canal Infection, Periapical Abscess | Not applicable | Completed | Dow University of Health Sciences | 100 | 2021-11-16 | 2023-10-26 |
| Ethanolic Extract of Sapindus Mukorrossi as Final Endodontic Irrigant. ethanolic extract of sapindus mukorossi, ethylene diamine tetra acetic acid - Irreversible Pulpitis, Apical Periodontitis | Not applicable | Completed | Dow University of Health Sciences | 90 | 2020-04-02 | 2021-09-08 |
| Smart Touch Non-dispensing Handling Studies Smart Touch Technology packaging, Conventional lens packaging, EDTA - Optometry | Not applicable | Completed | The University of New South Wales | 38 | 2018-06-04 | 2021-12-03 |
| Comparison of Antibacterial Efficacy of Three Final Irrigants QMix Root Canal Irrigant, 17%EDTA+2%Chlorhexidine, EDTA - Endodontic Disease, Root Canal Infection | Phase 2 / Phase 3 | Completed | Dow University of Health Sciences | 90 | 2017-04-03 | 2019-02-25 |
| Trial to Assess Chelation Therapy 2 disodium EDTA, Oral Multi Vitamins/Minerals (OMVM), Placebo disodium EDTA - Diabetes, Myocardial Infarction | Phase 3 | Completed | Mt. Sinai Medical Center, Miami | 1000 | 2016-10-01 | 2025-03-30 |
| Simvastatin Gel With Perforated Resorbable Membranes in Treatment of Intrabony Defects in Chronic Periodontitis Simvastatin, EDTA, Occlusive membrane - Chronic Periodontitis | Phase 4 | Completed | Ain Shams University | 40 | 2016-01-01 | 2018-02-06 |
| Efficacy of Chlorhexidine as a Final Irrigant in Single-visit Root Canal Treatment EDTA, NaOCl, CHX - Root Canal Infection | Not applicable | Completed | Mehmet Kemal Çalışkan | 82 | 2011-01-01 | 2017-11-08 |
| Trial to Assess Chelation Therapy (TACT) EDTA, EDTA Placebo, High Dose Vitamin - Coronary Artery Disease | Phase 3 | Completed | Mt. Sinai Medical Center, Miami | 1708 | 2003-09-01 | 2013-11-05 |
Periapical Periodontitis (2) · Chronic Periodontitis (1) · Coronary Artery Disease (1) · Dental Pulp Diseases (1) · Diabetes Mellitus (1) · Inflammation (1) · Myocardial Infarction (1) · Pain, Postoperative (1) · Periapical Abscess (1) · Stomatitis, Herpetic (1)
Dow University of Health Sciences (3) · Mt. Sinai Medical Center, Miami (2) · Ain Shams University (1) · Mehmet Kemal Çalışkan (1) · Suez Canal University (1) · The University of New South Wales (1) · University of Utah (1)
Pakistan (3) · United States (3) · Australia (1) · Canada (1) · Egypt (1)
Ahmed Y Gamal, Professor (1) · Araib AT Tahir, BDS (1) · Christopher M Hull, M.D. (1) · Dalia Abdallah (1) · Dalia Fayyad (1) · Daniel B Mark, MD (1) · Gervasio A Lamas, M.D. (1) · Gervasio A Lamas, MD (1) · Hasan Zaidi, BDS (1) · Kevin J Anstrom, PhD (1) · Sehrish Zubair (1)
PMID 22172430, PMID 23532240, PMID 24254885, PMID 24490264, PMID 24987051, PMID 32446881, PMID 33973914, PMID 39141382, PMID 40029647
R01AT009273 (1), U01AT001156 (1), U01HL092607 (1), U24AT009150 (1), UH3AT009149 (1), UH3AT009150 (1)