5 completed, 1 recruiting. 4 Phase 1, 3 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Completed 3, Recruiting 1 |
| Phase 2 | 3 | Completed 2, Recruiting 1 |
| Phase 3 | 1 | Completed 1 |
Follow DTX: new trials by email Literature Review of DTX trials Research Report on DTX
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate Cancer SX-682, DTX - Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma | Phase 1 / Phase 2 | Recruiting | National Cancer Institute (NCI) | 120 | 2026-10-29 | 2026-10-26 |
| A Phase 1/2 Study of CAN04 in Combination With Different Chemotherapy Regimens in Subjects With Advanced Solid Tumors CAN04 (nadunolimab), mFOLFOX, DTX - Advanced Solid Tumors, Colorectal Cancer | Phase 1 / Phase 2 | Completed | Cantargia AB | 40 | 2021-09-22 | 2023-07-03 |
| Camrelizumab in Combination With Chemotherapy or Apatinib Mesylate as First-Line Treatment for R/M HNSCC Camrelizumab, Cisplatin, Docetaxel - Recurrent Head and Neck Squamous Cell Carcinoma, Metastatic Head and Neck Squamous Cell Carcinoma | Phase 2 | Completed | Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University | 81 | 2021-06-24 | 2025-07-31 |
| A Feasibility Trial of Nivolumab With Neoadjuvant CF or DCF Therapy for Locally Advanced Esophageal Carcinoma Nivolumab, 5-FU, CDDP - Locally Advanced Esophageal Squamous Cell Carcinoma | Phase 1 | Completed | National Cancer Center, Japan | 37 | 2019-05-07 | 2025-05-31 |
| Study of Mogamulizumab + Docetaxel in Subjects With Non-small Cell Lung Cancer mogamulizumab, Docetaxel - Non-Small Cell Lung Cancer | Phase 1 | Completed | Kyowa Kirin, Inc. | 13 | 2015-01-01 | 2024-09-19 |
| National Surgical Adjuvant Study of Breast Cancer(N-SAS BC) 07 [RESPECT] trastuzumab monotherapy, trastuzumab and chemotherapy - Breast Cancer | Phase 3 | Completed | Comprehensive Support Project for Oncology Research | 275 | 2009-10-28 | 2019-10-21 |
Carcinoma, Non-Small-Cell Lung (2) · Squamous Cell Carcinoma of Head and Neck (2) · Biliary Tract Neoplasms (1) · Breast Neoplasms (1) · Carcinoma (1) · Carcinoma, Adenoid Cystic (1) · Colorectal Neoplasms (1) · Esophageal Squamous Cell Carcinoma (1) · Head and Neck Neoplasms (1) · Hypopharyngeal Neoplasms (1) · Laryngeal Neoplasms (1) · Nasopharyngeal Carcinoma (1) · Paranasal Sinus Neoplasms (1) · Prostatic Neoplasms (1) · Salivary Gland Neoplasms (1)
Cantargia AB (1) · Comprehensive Support Project for Oncology Research (1) · Kyowa Kirin, Inc. (1) · National Cancer Center, Japan (1) · National Cancer Institute (NCI) (1) · Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University (1)
Japan (2) · United States (2) · China (1) · France (1) · Spain (1)
Charalampos Floudas, M.D. (1) · Chenping Zhang, M.D. (1) · Ignacio Garcia-Ribas, MD, PhD (1) · Ken Kato, MD/PhD (1) · Masataka Sawaki (1) · Michael Kurman (1)
PMID 32396014, PMID 32936713, PMID 33835842, PMID 34080094, PMID 41188218