10 completed, 1 recruiting, 1 unknown. 12 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 12 | Completed 10, Recruiting 1, Unknown 1 |
Follow Digoxin: new trials by email Literature Review of Digoxin trials Research Report on Digoxin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Digoxin After Acute Heart Failure (DIG-DICA) Usual Care, Digoxin - Acute Heart Failure (AHF) | Phase 4 | Recruiting | Hospital General de Agudos "Dr. Cosme Argerich" | 120 | 2025-12-16 | 2026-06-02 |
| Effect of Estrogen Treatment on Drug Metabolism and Transport Midazolam oral solution, Digoxin Oral Tablet, Acetaminophen Oral Tablet - Transgender Persons | Phase 4 | Completed | University of Washington | 22 | 2022-11-01 | 2026-01-09 |
| Sodium-glucose Cotransporter Type 2 Inhibitors for Acute Cardiorenal Syndrome Prevention Standard list of drugs used for acute decompensation of CHF (loop diuretics, vasodilators, digoxin, inotropic agents, vasopressors), plus dapagliflozin (Forxiga; MP-002596) - Congestive Heart Failure | Phase 4 | Completed | I.M. Sechenov First Moscow State Medical University | 370 | 2021-01-01 | 2022-12-07 |
| Digoxin Evaluation in Chronic Heart Failure: Investigational Study In Outpatients in the Netherlands Digoxin, Placebos - Heart Failure | Phase 4 | Completed | University Medical Center Groningen | 982 | 2020-07-01 | 2026-04-27 |
| Intrafetal Digoxin as an Adjuvant for Dilation and Evacuation at 20 to 24 Weeks' Gestation Digoxin, Placebo - Abortion | Phase 4 | Completed | University of California, San Francisco | 178 | 2017-02-23 | 2019-10-30 |
| Rate Control Therapy Evaluation in Permanent Atrial Fibrillation (RATE-AF) Bisoprolol, Digoxin - Permanent Atrial Fibrillation | Phase 4 | Completed | University of Birmingham | 161 | 2016-12-20 | 2021-06-18 |
| Drug Transporter Interaction Study PHENTRA_2015_KPUK pitavastatin, Metformin, digoxin - Healthy | Phase 4 | Completed | University of Cologne | 24 | 2016-04-01 | 2019-09-10 |
| Digoxin Versus Ivabradine in Heart Failure With Reduced Ejection Fraction Digoxin, Ivabradine - Heart Failure | Phase 4 | Unknown | Kocaeli University | 60 | 2014-01-01 | 2014-01-27 |
| Clinical Trial to Evaluate the Influence of Genotype and DDIs of Aspirin on the PK/PD of Clopidogrel and PK of Digoxin Aspirin+Clopidogrel/Digoxin(oral), Aspirin+Clopidogrel/Digoxin(IV) - DRUG REACTIONS | Phase 4 | Completed | Seoul National University Hospital | 24 | 2013-01-01 | 2014-06-10 |
| Effect of Addition of Dronedarone to Standard Rate Control Therapy on Ventricular Rate During Persistent Atrial Fibrillation (AFRODITE) Dronedarone, Beta blocker or calcium antagonist or digoxin - Atrial Fibrillation | Phase 4 | Completed | Sanofi | 183 | 2010-04-01 | 2011-11-10 |
| Efficacy Study of Digoxin & Ivabradine to Treat Heart Failure Ivabradine, Digoxin - Cardiac Failure | Phase 4 | Completed | Cocco, Giuseppe, M.D. | 22 | 2008-04-01 | 2013-11-11 |
| Digoxin Dosing in Heart Failure: A Simplified Nomogram Versus Standard Care Digoxin Dosing per Nomogram, Digoxin - Heart Failure | Phase 4 | Completed | University of Illinois at Chicago | 131 | 2006-12-01 | 2014-05-22 |
Heart Failure (5) · Atrial Fibrillation (3) · Drug-Related Side Effects and Adverse Reactions (1) · Heart Failure, Systolic (1)
Cocco, Giuseppe, M.D. (1) · Hospital General de Agudos "Dr. Cosme Argerich" (1) · I.M. Sechenov First Moscow State Medical University (1) · Kocaeli University (1) · Sanofi (1) · Seoul National University Hospital (1) · University Medical Center Groningen (1) · University of Birmingham (1) · University of California, San Francisco (1) · University of Cologne (1) · University of Illinois at Chicago (1) · University of Washington (1)
United States (3) · Netherlands (2) · Argentina (1) · Germany (1) · Russia (1) · South Korea (1) · Switzerland (1) · Turkey (Türkiye) (1) · United Kingdom (1)
Dipak Kotecha, MBChB PhD MRCP (1) · Dirk J van Veldhuisen, MD, PhD (1) · Giuseppe Cocco, MD (1) · Guillermo Ernesto Liniado, MD (1) · In-Jin Jang, MD (1) · Kurtulus Karauzum, MD (1) · Michiel Rienstra, MD, PhD (1) · Peter van der Meer, MD, PhD (1) · Robert J DiDomenico, PharmD (1) · Uwe Fuhr, Prof. Dr. (1)
PMID 24765517, PMID 25164709, PMID 28729311, PMID 31247117, PMID 32719417, PMID 33351042, PMID 39009776, PMID 39212246, PMID 39819610, PMID 41462450, PMID 42108270
2008 (1), 2009 (1), K23GM147350 (1)