16 completed. 16 Phase 2, 4 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 16 | Completed 16 |
| Phase 1 | 4 | Completed 4 |
Follow dehydroftorafur: new trials by email Literature Review of dehydroftorafur trials Research Report on dehydroftorafur
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Linear Energy Transfer (LET)-Optimized Intensity Modulated Proton Therapy (IMPT) as a Component of Definitive Chemoradiation for Newly Diagnosed Squamous Cell Carcinoma of the Anal Canal: a Feasibility Trial Cisplatin, Fluorouracil, Linear Energy Transfer-Optimized Intensity Modulated Proton Therapy - Anal Canal Squamous Cell Carcinoma, Stage I Anal Cancer AJCC v8 | Phase 2 | Completed | M.D. Anderson Cancer Center | 8 | 2018-11-08 | 2023-06-29 |
| Avelumab in Combination With Fluorouracil and Mitomycin or Cisplatin and Radiation Therapy in Treating Participants With Muscle-Invasive Bladder Cancer Avelumab, Cisplatin, Fluorouracil - Bladder Carcinoma Infiltrating the Muscle of the Bladder Wall, Stage II Bladder Cancer AJCC v8 | Phase 2 | Completed | Mayo Clinic | 2 | 2018-09-19 | 2023-01-06 |
| Veliparib, Pembrolizumab, and Combination Chemotherapy in Treating Patient With Locally Advanced Rectal Cancer Capecitabine, Fluorouracil, Intensity-Modulated Radiation Therapy - Rectal Adenocarcinoma, Stage II Rectal Cancer AJCC v7 | Phase 2 | Completed | National Cancer Institute (NCI) | 363 | 2017-01-11 | 2025-12-04 |
| FOLFIRI or Modified FOLFIRI and Veliparib as Second Line Therapy in Treating Patients With Metastatic Pancreatic Cancer Fluorouracil, Irinotecan Hydrochloride, Laboratory Biomarker Analysis - Metastatic Pancreatic Adenocarcinoma, Recurrent Pancreatic Carcinoma | Phase 2 | Completed | National Cancer Institute (NCI) | 123 | 2016-10-27 | 2026-05-20 |
| Pembrolizumab, Combination Chemotherapy, and Radiation Therapy Before Surgery in Treating Adult Patients With Locally Advanced Gastroesophageal Junction or Gastric Cardia Cancer That Can Be Removed by Surgery Carboplatin, Computed Tomography, Fluorouracil - Gastric Cardia Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma | Phase 1 / Phase 2 | Completed | Mayo Clinic | 31 | 2016-06-24 | 2025-06-22 |
| Nab-paclitaxel and Gemcitabine Hydrochloride Followed by Radiation Therapy Before Surgery in Treating Patients With Pancreatic Cancer That Can Be Removed by Surgery Fluorouracil, Gemcitabine, Image Guided Radiation Therapy - Pancreatic Adenocarcinoma, Resectable Pancreatic Carcinoma | Phase 2 | Completed | OHSU Knight Cancer Institute | 20 | 2016-01-21 | 2023-09-06 |
| S1505: Combination Chemotherapy or Gemcitabine Hydrochloride and Paclitaxel Albumin-Stabilized Nanoparticle Formulation Before Surgery in Treating Patients With Pancreatic Cancer That Can Be Removed by Surgery Fluorouracil, Gemcitabine Hydrochloride, Irinotecan Hydrochloride - Pancreatic Adenocarcinoma, Resectable Pancreatic Carcinoma | Phase 2 | Completed | SWOG Cancer Research Network | 147 | 2016-01-06 | 2022-10-19 |
| BATS With in Combination With Low Dose IL-1 and GM-CSF for Advanced Pancreatic Cancer Aldesleukin, Antibody Therapy, Fluorouracil - Metastatic Pancreatic Adenocarcinoma, Recurrent Pancreatic Carcinoma | Phase 1 / Phase 2 | Completed | Barbara Ann Karmanos Cancer Institute | 2 | 2015-12-01 | 2023-05-15 |
| Trametinib or Combination Chemotherapy in Treating Patients With Refractory or Advanced Biliary or Gallbladder Cancer or That Cannot Be Removed by Surgery Capecitabine, Fluorouracil, Laboratory Biomarker Analysis - Adult Cholangiocarcinoma, Advanced Adult Hepatocellular Carcinoma | Phase 2 | Completed | National Cancer Institute (NCI) | 53 | 2014-02-01 | 2017-09-12 |
| Chemotherapy, Stereotactic Body Radiation Therapy & Nelfinavir Mesylate in Locally Advanced Pancreatic Cancer 4-Dimensional Computed Tomography, Fluorouracil, Gemcitabine Hydrochloride - Pancreatic Adenocarcinoma, Resectable Pancreatic Carcinoma | Phase 2 | Completed | University of Nebraska | 11 | 2013-09-06 | 2023-10-10 |
| Combination Chemotherapy With or Without Veliparib in Treating Patients With Stage IV Head and Neck Cancer Carboplatin, Cisplatin, Fluorouracil - Head and Neck Squamous Cell Carcinoma, Stage IVA Oropharyngeal Carcinoma AJCC v7 | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 24 | 2012-10-22 | 2023-06-07 |
| Selumetinib and Akt Inhibitor MK2206 or mFOLFOX Therapy Comprising Oxaliplatin and Fluorouracil in Treating Patients With Metastatic Pancreatic Cancer Previously Treated With Chemotherapy Akt Inhibitor MK2206, Fluorouracil, Oxaliplatin - Pancreatic Acinar Cell Carcinoma, Pancreatic Ductal Adenocarcinoma | Phase 2 | Completed | National Cancer Institute (NCI) | 137 | 2012-08-01 | 2016-03-09 |
| Alvocidib and Oxaliplatin With or Without Fluorouracil and Leucovorin Calcium in Treating Patients With Relapsed or Refractory Germ Cell Tumors Alvocidib Hydrochloride, Fluorouracil, Leucovorin Calcium - Recurrent Extragonadal Seminoma, Recurrent Malignant Extragonadal Germ Cell Tumor | Phase 2 | Completed | National Cancer Institute (NCI) | 36 | 2009-06-01 | 2017-03-10 |
| Bevacizumab, Cisplatin, Radiation Therapy, and Fluorouracil in Treating Patients With Stage IIB, Stage III, Stage IVA, or Stage IVB Nasopharyngeal Cancer 3-Dimensional Conformal Radiation Therapy, Bevacizumab, Cisplatin - Stage II Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7, Stage III Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7 | Phase 2 | Completed | National Cancer Institute (NCI) | 46 | 2006-12-13 | 2018-01-30 |
| Bevacizumab, Radiation Therapy, and Combination Chemotherapy in Treating Patients Who Are Undergoing Surgery for Locally Advanced Nonmetastatic Rectal Cancer Bevacizumab, Capecitabine, Fluorouracil - Rectal Adenocarcinoma, Stage II Rectal Cancer AJCC v7 | Phase 2 | Completed | National Cancer Institute (NCI) | 57 | 2006-07-25 | 2019-03-27 |
| Fluorouracil and Low-Dose Suramin as Chemosensitization in Treating Patients With Metastatic Renal Cell (Kidney) Cancer Fluorouracil, Pharmacological Study, Suramin - Recurrent Renal Cell Carcinoma, Stage IV Renal Cell Cancer | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 36 | 2004-03-01 | 2015-05-25 |
Pancreatic Neoplasms (4) · Rectal Neoplasms (2) · Anus Neoplasms (1) · Bile Duct Neoplasms (1) · Carcinoma, Hepatocellular (1) · Carcinoma, Renal Cell (1) · Cholangiocarcinoma (1) · Gallbladder Neoplasms (1) · Klatskin Tumor (1) · Oropharyngeal Neoplasms (1) · Squamous Cell Carcinoma of Head and Neck (1) · Stomach Neoplasms (1) · Testicular Neoplasms (1) · Ureteral Neoplasms (1) · Urethral Neoplasms (1)
National Cancer Institute (NCI) (9) · Mayo Clinic (2) · Barbara Ann Karmanos Cancer Institute (1) · M.D. Anderson Cancer Center (1) · OHSU Knight Cancer Institute (1) · SWOG Cancer Research Network (1) · University of Nebraska (1)
United States (16) · Canada (1) · Puerto Rico (1)
Anthony Shields (1) · Chi Lin (1) · Darren Feldman (1) · Davendra Sohal (1) · Elena G Chiorean (1) · Emma B Holliday (1) · Gina Vaccaro (1) · Harry H. Yoon, M.D. (1) · Jerome C Landry (1) · Jonas De Souza (1) · Nancy Lee (1) · Parminder Singh (1) · Richard Kim (1) · Ronald Bukowski (1) · Thomas J George (1)
PMID 22178121, PMID 25926352, PMID 27978579, PMID 32740235, PMID 32939319, PMID 33475684, PMID 34196693, PMID 37266942, PMID 37478389, PMID 38445914
U10CA180888 (4), U10CA032102 (2), N01CM00071 (1), N01CM62201 (1), N01CM62206 (1), P30CA008748 (1), P30CA022453 (1), P30CA036727 (1), R01CA093871 (1), U01CA062491 (1), U01CA062502 (1), U01CA062505 (1), U01CA069856 (1), U01CA069912 (1), U01CA099168 (1)