13 completed, 3 unknown, 2 recruiting, 2 terminated. 13 Not applicable, 2 Phase 3, 1 Phase 1, 1 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 13 | Completed 7, Terminated 2, Unknown 2, Not yet recruiting 1, Recruiting 1 |
| Phase 3 | 2 | Completed 2 |
| Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Completed 1 |
| Phase 4 | 1 | Unknown 1 |
Follow CytoSorb: new trials by email Literature Review of CytoSorb trials Research Report on CytoSorb
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Hemoadsorpion in Patients With Septic Shock: Efficacy and Safety Evaluation Efferon LPS, Toramyxin PMX 20R, Jafron HA 330 - Septic Shock | Not applicable | Not yet recruiting | Moscow Multidisciplinary Clinical Center "Kommunarka" | 76 | 2026-06-25 | 2026-07-02 |
| COOLEY- Study: aCute On chrOnic Liver failurE Using the cYtosorb Device CytoSorb - Acute-On-Chronic Liver Failure, Anticoagulant Adverse Reaction | Not applicable | Recruiting | University Hospital, Antwerp | 20 | 2024-06-08 | 2026-05-01 |
| CytOSorb TreatMent Of Critically Ill PatientS Registry CytoSorb - Septic Shock, Acute Respiratory Distress Syndrome | Recruiting | CytoSorbents, Inc | 3000 | 2022-06-22 | 2026-10-20 | |
| Cytokine Adsorption in Lung Transplantation CytoSorb - Lung Transplant Failure, Lung Transplant; Complications | Not applicable | Completed | Lund University Hospital | 20 | 2022-03-02 | 2023-09-08 |
| CytoSorb SAH Trial CytoSorb - Aneurysmal Subarachnoid Haemorrhage | Not applicable | Terminated | Emanuela Keller | 2 | 2022-01-31 | 2022-08-08 |
| Safe and Timely Antithrombotic Removal (STAR) Registry CytoSorb - Hemorrhage, Surgical, Hemorrhage Postoperative | Active not recruiting | CytoSorbents, Inc | 1000 | 2021-09-30 | 2026-10-21 | |
| Extracorporeal Cytokine Adsorption as Additive Treatment of CAR-T Associated Cytokine Release Syndrome (CRS) Cytosorb - Cytokine Release Syndrome, CAR-T | Not applicable | Unknown | Hannover Medical School | 34 | 2021-06-01 | 2021-04-01 |
| ECMOsorb Trial - Impact of a VA-ECMO in Combination With CytoSorb in Critically Ill Patients With Cardiogenic Shock CytoSorb, VA-ECMO only - Cardiogenic Shock | Not applicable | Completed | Christian Schulze | 42 | 2021-05-21 | 2026-02-04 |
| Cytokine Filter Usage During Open Thoracoabdominal Aortic Aneurysm Repair- a Single-center Randomized Prospective Trial Cytosorb - Postoperative Complications, Inflammatory Response | Completed | RWTH Aachen University | 20 | 2021-02-11 | 2024-04-10 | |
| Hemadsorption During and After Cardiopulmonary Bypass to Modulate the Inflammatory Response CytoSorb, Control - Inflammatory Response, Chronic Renal Disease | Not applicable | Unknown | University Magna Graecia | 40 | 2020-11-15 | 2020-11-12 |
| Determination of the Hemoadsorption Impact as Adjunctive Treatment Upon the Support Therapy of COVID-19 CytoSorb - Covid19 | Not applicable | Completed | Dr David DE BELS | 24 | 2020-05-03 | 2022-03-04 |
| Hemodynamic Impact of Cytosorb and CKRT in Children With Septic Shock Cytosorb - Septic Shock | Not applicable | Completed | Ospedale Pediatrico Bambin Gesù | 17 | 2019-09-01 | 2022-12-21 |
| Does Whole Blood Adsorber During CPB Reduce Vasoactive Drugs Postoperatively in Endocarditis Patients Undergoing Valve Surgery? CytoSorb - Infective Endocarditis | Not applicable | Completed | Emma Hansson | 20 | 2019-05-15 | 2021-09-22 |
| CytoSorb® Reduction of FREee Hemoglobin/Acute Kidney Injury (AKI) During Cardiac Surgery CytoSorb - Elective Cardiac Surgery | Not applicable | Terminated | CytoSorbents, Inc | 186 | 2018-04-19 | 2024-12-04 |
| Pancreatitis CytoSorbents (CytoSorb®) Inflammatory Cytokine Removal CytoSorb - Pancreatitis, Acute, SIRS | Phase 4 | Unknown | Technical University of Munich | 30 | 2017-03-15 | 2017-03-17 |
| Effects of Renal Replacement Therapy With Hemoadsoption in Patients With Sepsis CytoSorb - Sepsis | Completed | Institutul Clinic Fundeni | 30 | 2016-07-10 | 2021-09-13 | |
| Effect of Cytosorb on Blood Levels of Inflammatory Biomarkers of Sepsis. Cytokine aphaeresis - Sepsis, Cytokine Storm | Completed | University of Gaziantep | 34 | 2016-06-01 | 2020-01-13 | |
| Cytokine Clearance With Cytoabsorbant Device During Cardiac Bypass Cytosorb - Myocardial Ischemia, Heart Valve Diseases | Phase 1 / Phase 2 | Completed | Centre Hospitalier Universitaire Vaudois | 30 | 2016-05-01 | 2018-01-25 |
| Extracorporeal Cytokine Adsorption in Cardiac Surgery CytoSorb, Methylprednisolone - Cardiopulmonary Bypass | Phase 3 | Completed | University Medical Centre Ljubljana | 60 | 2016-02-01 | 2020-03-25 |
| CytoSorb Reduction of Free Hemoglobin During Cardiac Surgery CytoSorb - Elective Cardiac Surgery | Not applicable | Completed | CytoSorbents, Inc | 52 | 2015-11-01 | 2021-08-20 |
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Cytokine Release Syndrome (4) · Shock, Septic (4) · Sepsis (3) · Acute-On-Chronic Liver Failure (2) · Inflammation (2) · Multiple Organ Failure (2) · Pancreatitis (2) · Shock, Cardiogenic (2) · Acute Kidney Injury (1) · Blood Loss, Surgical (1) · Burns (1) · COVID-19 (1) · Communicable Diseases (1) · Diabetes Insipidus (1) · Drug Overdose (1)
CytoSorbents, Inc (4) · Centre Hospitalier Universitaire Vaudois (1) · Christian Schulze (1) · Dr David DE BELS (1) · Emanuela Keller (1) · Emma Hansson (1) · Hannover Medical School (1) · Institutul Clinic Fundeni (1) · Lund University Hospital (1) · Medical University of Vienna (1) · Moscow Multidisciplinary Clinical Center "Kommunarka" (1) · Ospedale Pediatrico Bambin Gesù (1) · RWTH Aachen University (1) · Technical University of Munich (1) · University Hospital, Antwerp (1)
Germany (5) · Switzerland (4) · Austria (3) · Belgium (3) · Italy (3) · Sweden (3) · United States (2) · Poland (1) · Portugal (1) · Romania (1) · Russia (1) · Slovenia (1) · Spain (1) · United Kingdom (1)
Andreas Spittler, MD (1) · Christian Schulze, Prof. (1) · Dana Tomescu, Prof (1) · Denis Protsenko, MD, PHD (1) · Dominik Wiedemann, MD (1) · Emma Hansson, MD PhD (1) · Friedrich Hoffelner (1) · Giuseppe Serraino, MD (1) · Gordana Taleska, MD, MSc (1) · Karolien Dams (1) · Maja Sostaric, MD, PhD (1) · Marco Maggiorini, MD (1) · Martin H Bernardi, MD (1) · Matej Podbregar, MD, PhD (1)
PMID 22429562, PMID 27052747, PMID 27059056, PMID 28389120, PMID 30681551, PMID 30944029, PMID 31936597, PMID 32113143, PMID 32292492, PMID 32414386, PMID 32573283, PMID 35011653, PMID 36983259, PMID 37240843, PMID 37607074, PMID 37780052, PMID 37855706, PMID 38709456, PMID 39500494, PMID 39833891, PMID 40044567, PMID 40933270, PMID 41180104
2015 (1)