5 unknown, 3 completed, 2 not yet recruiting, 2 recruiting. 13 Phase 3, 6 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 13 | Unknown 5, Completed 3, Not yet recruiting 2, Recruiting 2, Terminated 1 |
| Phase 2 | 6 | Unknown 3, Completed 1, Not yet recruiting 1, Recruiting 1 |
Follow Cryotherapy: new trials by email Literature Review of Cryotherapy trials Research Report on Cryotherapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of Cryotherapy Followed by Tirbanibulin Ointment for Actinic Keratosis on the Scalp and Forehead Cryotherapy + Tirbanibulin - Keratosis, Actinic Keratoses | Phase 3 | Not yet recruiting | University Hospital, Lille | 59 | 2026-11-30 | 2026-05-22 |
| Topical Cryotherapy and Keloid/Hypertrophic Scars Cryotherapy with liquid nitrogen, Intralesional Triamcinolone 10 mg/ml - Keloid Scars, Hypertrophic Scars | Phase 3 | Recruiting | Sonal Choudhary | 30 | 2026-06-10 | 2026-06-12 |
| Efficacy and Safety of Platelet-rich Plasma, Metformin and Cryotherapy in Treatment of Non-genital Warts platelet-rich plasma, Metformin, cryotherapy - Non-Genital Warts | Phase 2 / Phase 3 | Not yet recruiting | Assiut University | 108 | 2024-11-14 | 2024-11-15 |
| Intralesional Acyclovir Versus Cryotherapy in the Treatment of Plantar Warts. A Randomized Controlled Trial. Intralesional Acyclovir, Cryotherapy - Plantar Wart | Phase 2 / Phase 3 | Unknown | Cairo University | 92 | 2023-10-01 | 2024-02-15 |
| Ocular Conservative Treatment for Retinoblastoma : Efficacy of the New Management Strategies and Visual Outcome Melphalan or Melphalan + Topotecan, etoposide, carboplatin and vincristine or local ophthalmological treatment without IV chemotherapy, Carboplatin administered on Day 1 - Retinoblastoma | Phase 2 / Phase 3 | Recruiting | Institut Curie | 225 | 2021-03-25 | 2025-11-28 |
| Effect of Cryotherpy on Hypertrophic Scar cryotherapy (Gymna Cryoflow ICE-CT), Exercising, Positioning and splinting, Pressure Therapy and Massage - Hypertrophic Scars | Phase 2 / Phase 3 | Unknown | Zakria Mowafy | 60 | 2019-04-15 | 2020-08-31 |
| Comparison Between Tuberculin Vaccine and Cryotherapy in Genital Wart Patients tuberculin, cryotherapy - Genital Wart | Phase 3 | Unknown | Assiut University | 45 | 2017-06-01 | 2017-05-17 |
| A Sequential Treatment Regimen of Cryotherapy and Picato® for the Treatment of Actinic Keratosis on the Face and Scalp Cryotherapy, Vehicle, Ingenol metabute - Actinic Keratosis | Phase 3 | Completed | LEO Pharma | 367 | 2012-03-01 | 2025-03-10 |
| Study of Ablation for the Pulmonary Focal Pure Ground Glass Opacity (pGGO) cryotherapy or radiofrequency ablation - Pulmonary Lesions | Phase 3 | Unknown | Dongfang Hospital Beijing University of Chinese Medicine | 100 | 2011-09-01 | 2011-09-07 |
| Comparison Between 5-aminolevulinic Acid Photodynamic Therapy Versus Cryotherapy for Actinic Keratosis Treatment 5-ALA Photodynamic Therapy, Cryotherapy with liquid nitrogen - Actinic Keratosis | Phase 3 | Completed | Barretos Cancer Hospital | 137 | 2010-11-01 | 2017-06-28 |
| The Efficacy and Cost Effectiveness of Preoperative and Postoperative Cryotherapy in Proximal Tibia Fractures Cryotherapy, Room temperature cuff - Proximal Tibia Fracture | Phase 3 | Terminated | University of Manitoba | 20 | 2010-04-01 | 2017-05-08 |
| Cyrotherapy vs. APC in GAVE cryotherapy, Argon Plasma Coagulation - Watermelon Stomach | Phase 2 / Phase 3 | Completed | Mayo Clinic | 60 | 2007-12-01 | 2016-01-07 |
| Ablatherm Integrated Imaging High Intensity Focused Ultrasound for the Indication of Low Risk, Localized Prostate Cancer Integrated Imaging High Intensity Focused Ultrasound, Endocare CRYOcare Cryosurgical and Galil Medical CRYO-HIT Systems (cryotherapy) - Prostate Cancer | Phase 2 / Phase 3 | Unknown | EDAP TMS S.A. | 141 | 2006-04-01 | 2014-02-07 |
Keratosis, Actinic (3) · Cicatrix, Hypertrophic (2) · Condylomata Acuminata (1) · Gastric Antral Vascular Ectasia (1) · Keloid (1) · Keratosis (1) · Prostatic Neoplasms (1) · Retinoblastoma (1) · Tibial Plateau Fractures (1)
Assiut University (2) · Barretos Cancer Hospital (1) · Cairo University (1) · Dongfang Hospital Beijing University of Chinese Medicine (1) · EDAP TMS S.A. (1) · Institut Curie (1) · LEO Pharma (1) · Mayo Clinic (1) · Sonal Choudhary (1) · University Hospital, Lille (1) · University of Manitoba (1) · Zakria Mowafy (1)
United States (4) · Canada (2) · Egypt (2) · Brazil (1) · China (1) · France (1)
Brian Berman, MD, Ph.D (1) · Carey Robertson, MD (1) · Catarina Robert, MD (1) · Jesse A Shantz, MD, MBA (1) · Louis M Wongkeesong, MD (1) · Shahira Ramadan, Professor (1) · Sonal Choudhary (1) · Weisheng Chen, MD (1) · Yousra Azzazi, Lecturer (1)
PMID 11238198, PMID 12807939, PMID 15897380, PMID 16973081, PMID 23336207, PMID 24509965, PMID 24918567, PMID 25273231