3 completed, 3 terminated, 2 recruiting, 1 unknown. 6 Phase 1, 2 Phase 2, 1 Early Phase 1, 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 6 | Completed 2, Terminated 2, Recruiting 1, Unknown 1 |
| Phase 2 | 2 | Completed 1, Terminated 1 |
| Early Phase 1 | 1 | Completed 1 |
| Not applicable | 1 | Recruiting 1 |
Follow Copper Gluconate: new trials by email Literature Review of Copper Gluconate trials Research Report on Copper Gluconate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Copper Supplementation in Cirrhosis Copper Gluconate - Cirrhosis, Chronic Liver Disease | Not applicable | Recruiting | University of Washington | 30 | 2026-03-15 | 2026-03-13 |
| Disulfiram With Copper Gluconate and Liposomal Doxorubicin in Treatment-Refractory Sarcomas Disulfiram, Copper Gluconate, Liposomal Doxorubicin (Doxil) - Relapsed Sarcomas | Phase 1 | Recruiting | Case Comprehensive Cancer Center | 24 | 2023-03-09 | 2026-08-06 |
| Study of Disulfiram and Copper Gluconate in Patients With Treatment-Refractory Multiple Myeloma Disulfiram, Copper Gluconate - Multiple Myeloma | Phase 1 | Terminated | University of Utah | 2 | 2021-05-21 | 2023-03-13 |
| Disulfiram and Copper Gluconate With Temozolomide in Unmethylated Glioblastoma Multiforme Disulfiram, Copper gluconate, Temozolomide - Glioblastoma, Glioblastoma Multiforme | Phase 2 | Terminated | Wake Forest University Health Sciences | 15 | 2018-03-28 | 2024-10-03 |
| A Phase Ib Study of Intravenous Copper Loading With Oral Disulfiram in Metastatic, Castration Resistant Prostate Cancer Copper, Disulfiram, Copper gluconate - Prostate Cancer | Phase 1 | Terminated | Daniel George, MD | 9 | 2017-07-11 | 2021-09-16 |
| Disulfiram/Copper With Concurrent Radiation Therapy and Temozolomide in Patients With Newly Diagnosed Glioblastoma Disulfiram, Copper Gluconate, Surgery - Glioblastoma Multiforme | Phase 1 / Phase 2 | Completed | Washington University School of Medicine | 35 | 2016-06-15 | 2025-04-10 |
| Disulfiram in Treating Patients With Glioblastoma Multiforme After Radiation Therapy With Temozolomide Temozolomide, Disulfiram, Copper gluconate - Glioblastoma | Early Phase 1 | Completed | Washington University School of Medicine | 21 | 2013-10-10 | 2018-07-20 |
| Human Biomarkers for Assessing Copper Deficiency Copper gluconate - Copper Deficiency | Phase 1 | Unknown | Purdue University | 70 | 2010-11-01 | 2017-04-19 |
| Phase I Study of Disulfiram and Copper Gluconate for the Treatment of Refractory Solid Tumors Involving the Liver Disulfiram, Copper Gluconate - Cancer | Phase 1 | Completed | University of Utah | 21 | 2008-07-01 | 2014-10-31 |
Glioblastoma (3) · Fibrosis (1) · Infections (1) · Malnutrition (1) · Multiple Myeloma (1) · Neoplasms (1) · Osteosarcoma (1) · Prostatic Neoplasms (1) · Rhabdomyosarcoma (1) · Sarcoma (1) · Sarcoma, Ewing (1)
University of Utah (2) · Washington University School of Medicine (2) · Case Comprehensive Cancer Center (1) · Daniel George, MD (1) · Purdue University (1) · University of Washington (1) · Wake Forest University Health Sciences (1)
United States (9)
Jiayi Huang, M.D. (2) · Asadullah Khan, MD (1) · Daniel George, MD (1) · Douglas Sborov, MD (1) · Kenneth Grossmann, MD, PhD (1) · Lei Yu, MD (1) · Matteo Trucco, MD (1)
PMID 24344045, PMID 33957901, PMID 35285015, PMID 38768767
R01DK142802 (1)