9 completed, 1 active not recruiting, 1 terminated. 4 Not applicable, 3 Phase 3, 2 Phase 2, 2 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 4 | Completed 3, Active not recruiting 1 |
| Phase 3 | 3 | Completed 3 |
| Phase 2 | 2 | Completed 1, Terminated 1 |
| Phase 4 | 2 | Completed 2 |
Follow Control Toothpaste: new trials by email Literature Review of Control Toothpaste trials Research Report on Control Toothpaste
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of a Toothpaste Containing a Gum Health Active in Participants With Gingival Problem Test Toothpaste, Control Toothpaste - Gingival Inflammation, Gingival Bleeding | Not applicable | Active not recruiting | Unilever R&D | 150 | 2026-02-27 | 2026-09-15 |
| Hypersensitivity Reduction Efficacy: 5% Potassium Nitrate Toothpaste Compared to Colgate Cavity Protection Toothpaste test toothpaste, Control toothpaste - Dentin Hypersensitivity | Phase 3 | Completed | Colgate Palmolive | 80 | 2025-05-10 | 2026-03-19 |
| Clinical of Hypersensitivity Reduction Efficacy on Two Toothpastes Test toothpaste, Control toothpaste - Hypersensitivity | Phase 3 | Completed | Colgate Palmolive | 87 | 2024-10-08 | 2025-04-22 |
| Fluoride vs Probiotic Toothpaste for Caries Prevention Fluoride toothpaste, Probiotic Toothpaste, Control Toothpaste - Dental Caries, Child Behavior | Phase 4 | Completed | The Affiliated Hospital of Qingdao University | 508 | 2023-01-01 | 2026-05-12 |
| Investigation of the Instant Tooth Whitening Effect of a Silica Toothpaste Containing Blue Covarine Blue covarine toothpaste, Control toothpaste - Tooth Whitening | Not applicable | Completed | University of Aarhus | 24 | 2018-11-13 | 2019-11-19 |
| Effect of Over-the-counter Toothpastes on Chemotherapy-induced Oral Mucositis Oral Defense Toothpaste, Crest Toothpaste, Magic Mouth Rinse - Mucositis, Neoplasms | Phase 2 | Terminated | Oral Defense, LLC | 1 | 2018-05-29 | 2019-02-06 |
| Whitening Efficacy of Dentifrice Containing 10% High Cleaning Silica, 0.5% Sodium Phytate and 0.5% Sodium Pyrophosphate Toothpaste containing 10% high cleaning silica base, 0.5% sodium phytate and 0.5% sodium pyrophosphate, Control toothpaste - Tooth Bleaching | Not applicable | Completed | Sun Yat-sen University | 86 | 2018-05-07 | 2022-02-23 |
| Evaluation of the Effect of Zinc Citrate Trihydrate Toothpaste on the Oral Plaque Microbiome ZCT toothpaste, Control toothpaste - Dental Plaque | Not applicable | Completed | Unilever R&D | 142 | 2017-01-10 | 2024-04-11 |
| Clinical Investigation of the Effects of Colgate Total Toothpaste as Compared to a Matching Placebo on Periodontal Disease and Systemic Inflammatory Markers Triclosan Containing Toothpaste, Triclosan Free Toothpaste - Periodontal Disease, Systemic Inflammatory Markers | Phase 4 | Completed | Colgate Palmolive | 303 | 2015-06-01 | 2019-02-22 |
| The Clinical Investigation of a Zinc Based Toothpaste in Reducing Plaque and Gingivitis Control toothpaste, Experimental toothpaste, Active Comparator - Dental Plaque and Gingivitis | Phase 2 | Completed | Colgate Palmolive | 162 | 2014-12-01 | 2019-02-25 |
| Effects of Antioxidant Dentifrice on Gingivitis Experimental toothpaste, Control toothpaste - Gingivitis | Phase 3 | Completed | Lion Corporation | 300 | 2006-09-01 | 2014-04-02 |
Dental Plaque (3) · Gingivitis (3) · Child Behavior (1) · Dental Caries (1) · Dentin Sensitivity (1) · Gingival Hemorrhage (1) · Hypersensitivity (1) · Mucositis (1) · Neoplasms (1) · Periodontal Diseases (1) · Stomatitis (1)
Colgate Palmolive (4) · Unilever R&D (2) · Lion Corporation (1) · Oral Defense, LLC (1) · Sun Yat-sen University (1) · The Affiliated Hospital of Qingdao University (1) · University of Aarhus (1)
China (4) · Denmark (1) · Dominican Republic (1) · Indonesia (1) · Japan (1) · United States (1)
Arvind Chaudhry, MD,PhD (1) · Deyu Hu, DDS, MS (1) · Hongchun Liu, Ph.D. (1) · Robert Maclure, BDS (1) · Sebastian Schlafer, Dr. (1) · Shinya Murakami (1)