Chlorhexidine mouthwash: Clinical Trials

45 trials of Chlorhexidine mouthwash, newest first

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21 completed, 15 unknown, 3 not yet recruiting, 3 recruiting. 24 Not applicable, 8 Phase 2, 8 Phase 3, 5 Phase 1, 5 Phase 4.

By phase and status

PhaseTrialsStatus
Not applicable24Completed 12, Unknown 7, Not yet recruiting 2, Recruiting 2, Enrolling by invitation 1
Phase 28Completed 5, Unknown 2, Not yet recruiting 1
Phase 38Completed 3, Unknown 2, Active not recruiting 1, Not yet recruiting 1, Recruiting 1
Phase 15Completed 2, Unknown 2, Withdrawn 1
Phase 45Unknown 3, Completed 2

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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Anticariogenic Effect of Moringa Oleifera Mouthwash Compared to Chlorhexidine Mouthwash
Moringa Oleifera, Chlorhexidine mouthwash, Base formula - Plaque, Dental, Antimicrobial
Phase 2 / Phase 3Not yet recruitingMisr International University902027-12-012026-10-08
Effectiveness of Coconut Oil Pulling and Moringa Mouthwash Versus Chlorhexidine in Reducing Gingivitis in Diabetic Children
Chlorhexidine mouthwash, Moringa olfera mouthwash, coconut oil pulling - Reducing Gingivitis, Clinical Effect
Not applicableNot yet recruitingAmira Yehia Zakaria302026-10-012026-09-22
Virgin Coconut Oil Versus Chlorhexidine Mouthwash in Non-Surgical Periodontal Therapy of Periodontitis Patients. A Randomized Controlled Clinical Trial With Biochemical Assessment.
Non-surgical periodontal therapy, Chlorhexidine mouthwash, Virgin coconut oil mouthwash - Stage II Periodontitis
Not applicableNot yet recruitingAin Shams University422026-07-012026-07-15
PMPR and Chlorhexidine on Periodontal Disease and Vascular Function
Chlorhexidine (0.2%) mouthwash, Placebo mouthwash - Periodontal Disease (PD), Cardio Vascular Disease
Not applicableRecruitingMahdi Mutahar302026-01-232026-03-25
Comparison Of Clinical Effects Of Listerine And Chlorhexidine Mouth Wash In Patients Undergoing Fixed Orthodontic Treatment
Listerine Mouthwash Product, Chlorhexidine mouthwash - Gingivitis, Dental Plaque
Not applicableCompletedKhyber Medical University Peshawar602025-08-012026-08-13
The Effect of Chamomile on Healing After Tooth Extraction
Physiological serum mouthwash, Chlorhexidine mouthwash, Chamomile mouthwash - Tooth Extraction Status Nos
Not applicableCompletedreyhan saglam-dogu1202025-01-012026-08-27
Oral Care With 3% Hydrogen Peroxide (Oroxid®) in ICU - Effects on the Lower Airway Microbial Colonisation
Oroxid®, Chlorhexidine mouthwash - VAP - Ventilator Associated Pneumonia
Phase 4UnknownCharles University, Czech Republic1602024-05-012024-07-26
Investigating the Effect of Chlorine Dioxide and Chlorhexidine Mouthwash on Bad Breath
Chlorine dioxide mouthwash, Chlorhexidine mouthwash - Halitosis
Not applicableEnrolling by invitationSemmelweis University602024-04-182025-08-05
Clinical Efficacy of Saffron Mouth Rinse in Periodontitis Patients With Renal Disease
Saffron, chlorhexidine mouthwash - Periodontal Diseases, Periodontal Pocket
Not applicableUnknownBritish University In Egypt202024-01-012024-01-31
The Effect of Chlorhexidine on the Oral Microbiome and Saliva in Dental Erosion
Chlorhexidine mouthwash - Dental Erosion
Not applicableUnknownUniversity of Portsmouth242023-12-202023-12-14
Compare the Effect of Green Tea Mouthwash vs Chlorohexidine Mouthwash in Children With Plaque-induced Gingivitis
Green tea mouthwash, Chlorhexidine mouthwash - Plaque Induced Gingivitis
Not applicableUnknownCairo University802023-05-012023-04-07
Ozonated Water in Treatment of Denture Stomatitis
Ozonated water, Chlorhexidine mouthwash - Denture Stomatitis
Not applicableCompletedNational Research Centre, Egypt502023-05-012023-09-01
Anti-inflammatory and Anti-plaque Efficacies of Mouth Rinse Containing Hyaluronic Acid and Hydrogen Peroxide
Perhyal rinse, Chlorhexidine mouthwash, Placebo - Plaque Induced Gingivitis, Mouth Diseases
Phase 3CompletedUniversity of Baghdad542023-03-032023-10-04
The Effect of Post-surgical Chlorhexidine Mouth Washing on the Sub-gingival Periodontal Microbiome A Pilot Study
Corsodyl - Periodontitis, Subgingival Plaque
UnknownRambam Health Care Campus302023-02-032023-03-30
Chlorhexidine Mouthwash and Oral Nitrate in Adults With Pulmonary Hypertension
Nitrates, Chlorhexidine Gluconate Mouthwash, Placebo Mouthwash - Pulmonary Hypertension, Heart Failure With Normal Ejection Fraction
Phase 1WithdrawnGladwin, Mark, MD2022-12-012022-07-07
Therapeutic Application of Coconut Oil in Oral Health
Coconut Oil, Chlorhexidine mouthwash, Water mouthwash - Periodontal Diseases, Periodontal Inflammation
Not applicableCompletedFundacion Clinica Pardinas302022-11-012025-02-26
The Effect of Chlorhexidine Mouthwash on Postprandial Glucose Response in Healthy Individuals
Chlorhexidine mouthwash, Placebo mouthwash - Glucose Metabolism Disorders (Including Diabetes Mellitus)
Not applicableRecruitingUniversity of Plymouth452022-06-082025-09-19
The Effect of Smoking and Chlorhexidine on Periodontal Tissues After Non- Surgical Periodontal Therapy in Patients With Periodontitis
non surgical periodontal therapy, Chlorhexidine mouthwash - Smoking, Periodontitis
Not applicableUnknownUniversity of Rijeka602022-03-142024-01-05
Comparative Evaluation of Propolis Mouthwash With 0.2% Chlorhexidine Mouthwash in Improving the Periodontitis
Propolis mouthwash, Chlorhexidine mouthwash - Periodontal Diseases
Phase 2CompletedZiauddin University1022022-02-022023-05-23
Dental Biofilm Control During Orthodontic Treatment
fixed metal orthodontic appliance, fixed non-metal orthodontic appliance, oral hygiene - Gingivitis, Malocclusion
Phase 3Active not recruitingUniversity of Rijeka802021-11-012026-01-30

Showing 20 of 45. Sign in to see all of them.

Conditions studied

Gingivitis (8)  ·  Periodontal Diseases (8)  ·  Dental Plaque (5)  ·  Periodontitis (5)  ·  Dental Caries (4)  ·  Gingival Hemorrhage (3)  ·  Hemorrhage (3)  ·  Plaque, Amyloid (3)  ·  Halitosis (2)  ·  Infections (2)  ·  Pneumonia (2)  ·  Postoperative Complications (2)  ·  Communicable Diseases (1)  ·  Dental Calculus (1)  ·  Dry Socket (1)

Sponsors

Cairo University (4)  ·  Semmelweis University (2)  ·  University of Baghdad (2)  ·  University of Milan (2)  ·  University of Plymouth (2)  ·  University of Rijeka (2)  ·  Ziauddin University (2)  ·  Ain Shams University (1)  ·  Amira Yehia Zakaria (1)  ·  British University In Egypt (1)  ·  Charles University, Czech Republic (1)  ·  Damascus University (1)  ·  Dr. Krupa NC (1)  ·  Fundacion Clinica Pardinas (1)  ·  Gladwin, Mark, MD (1)

Countries

Egypt (8)  ·  Pakistan (4)  ·  United Kingdom (4)  ·  India (3)  ·  Saudi Arabia (3)  ·  Croatia (2)  ·  Hungary (2)  ·  Iraq (2)  ·  Italy (2)  ·  Turkey (Türkiye) (2)  ·  Belgium (1)  ·  Brazil (1)  ·  Czechia (1)  ·  Israel (1)  ·  Malaysia (1)

Top investigators

Giampietro Farronato, Professor (2)  ·  Gianguido Cossellu, Fellow (2)  ·  Abdul Hakim Nattouf, Professor (1)  ·  Ahmed Amr, Professor (1)  ·  Alison Morris, MD, MS (1)  ·  Asmaa N, Elboraey, Ass,Pro (1)  ·  Chaza Kouchaji, Professor (1)  ·  Dalia Ghalwash (1)  ·  Doaa Adnan Alnouri, DDS, Msc Student (1)  ·  Dr Naveed Sadiq, PhD (1)  ·  Dr.Chandrika Dubey, MDS (1)  ·  Eid Muhammad, MPHIL (1)  ·  Fazli Rabi, MPH* (1)

Results publications

PMID 19336860, PMID 23489103, PMID 24060558, PMID 25838632, PMID 31111439, PMID 32923724, PMID 35080344, PMID 35287956, PMID 35866376, PMID 35968060, PMID 37214190, PMID 37867062, PMID 37881795, PMID 38148481, PMID 38183081, PMID 38202328, PMID 38582863, PMID 38769314, PMID 39012233, PMID 40085302, PMID 40255646, PMID 41140336, PMID 41376890, PMID 42057009, PMID 42836614

NIH funding

2018 (1), P01HL103455 (1)