5 completed, 1 recruiting, 1 unknown. 7 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 7 | Completed 5, Recruiting 1, Unknown 1 |
| Phase 1 | 1 | Unknown 1 |
| Phase 3 | 1 | Completed 1 |
Follow Cefixime: new trials by email Literature Review of Cefixime trials Research Report on Cefixime
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Optimizing the Diagnostic Approach to Cephalosporin Allergy Testing Beta-lactam antibiotic (cefazolin, cefuroxime, cefotaxime, ceftazidime, ceftriaxone, cefepime, pre-pen, penicillin G, ampicillin, and histamine) double-blind skin testing, Culprit cephalosporin (cefazolin, ceftazidime, ceftriaxone, cefepime, cephalexin, cefaclor, cefadroxil, cefuroxime, cefpodoxime, cefdinir, or cefixime) double-blind placebo-controlled drug challenge, Similar cephalosporin (cefepime, ceftriaxone, cefaclor, cephalexin, cefixime, or cefdinir) antibiotic double-blind placebo-controlled drug challenge - Drug Allergy, Cephalosporin Allergy | Phase 2 | Recruiting | Massachusetts General Hospital | 300 | 2025-05-05 | 2026-11-12 |
| Efficacy of Immunization With 4C-MenB in Preventing Experimental Urethral Infection With Neisseria Gonorrhoeae Cefixime, Ceftriaxone, Ciprofloxacin - Gonorrhea Male | Phase 2 | Completed | University of North Carolina, Chapel Hill | 65 | 2022-04-18 | 2026-03-02 |
| Comparison of Efficacy of Two Combination Regimens for the Neisseria Gonorrhoeae and Chlamydia Coinfection Ceftriaxone 1000mg + doxycycline 100 mg, Cefixime 800mg + doxycycline 100 mg - Neisseria Gonorrhoeae Infection, Chlamydia Trachomatis Infection | Phase 2 | Completed | Haiphong University of Medicine and Pharmacy | 125 | 2021-07-15 | 2022-03-17 |
| Combination Antibiotic Therapy Compared to Monotherapy in the Treatment of Acute COPD Beta-Lactams, Fluoroquinolone - COPD Exacerbation Acute | Phase 2 / Phase 3 | Completed | Haiphong University of Medicine and Pharmacy | 170 | 2020-01-01 | 2021-05-10 |
| Trial Evaluating the Clinical Efficacy of Cefixime for Treatment of Early Syphilis in Non-pregnant Women Cefixime, Benzathine penicillin 2.4 million units - Syphilis Female | Phase 1 / Phase 2 | Unknown | World Health Organization | 180 | 2019-11-22 | 2020-02-05 |
| Cefixime for Alternative Syphilis Treatment Cefixime 400 milligram Oral Capsule [Suprax], Benzathine Penicillin G - Syphilis, Early Syphilis | Phase 2 | Completed | University of California, Los Angeles | 58 | 2018-09-03 | 2022-07-26 |
| The SCOUT Study: "Short Course Therapy for Urinary Tract Infections in Children" Cefixime, Cephalexin, Placebo - Urinary Tract Infection | Phase 2 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 717 | 2012-05-18 | 2020-08-06 |
Syphilis (2) · Anaphylaxis (1) · Drug Hypersensitivity (1) · Escherichia coli Infections (1) · Gonorrhea (1) · Hypersensitivity (1) · Reinfection (1) · Sexually Transmitted Diseases (1) · Urinary Tract Infections (1)
Haiphong University of Medicine and Pharmacy (2) · Massachusetts General Hospital (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · University of California, Los Angeles (1) · University of North Carolina, Chapel Hill (1) · World Health Organization (1)
United States (4) · Vietnam (2) · Brazil (1)
David A Khan, MD (1) · David Tellalian, MD (1) · Edna O Kara, MD (1) · Jeffrey D Klausner, MD MPH (1) · Joseph A Duncan, MD, PhD (1) · Kimberly G Blumenthal, MD, MSc (1) · Melanie M Taylor, MD (1) · Nathalie JN Broutet, MD (1) · Phuong Nguyen, PhD (1) · Phuong TT Nguyen, PhD MD (1)
PMID 32522244, PMID 33298143, PMID 33640982, PMID 35810277, PMID 37358858, PMID 40086037, PMID 42049314
U01AI162457 (1), U01AI184071 (1)