6 completed, 5 unknown, 2 active not recruiting, 1 recruiting. 14 Phase 2, 7 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 14 | Completed 6, Unknown 5, Active not recruiting 2, Recruiting 1 |
| Phase 3 | 7 | Unknown 4, Completed 2, Recruiting 1 |
Follow Calcium Hydroxide: new trials by email Literature Review of Calcium Hydroxide trials Research Report on Calcium Hydroxide
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of Postoperative Pain and Bacterial Load After Hyalone or Calcium Hydroxide Medication in Mandibular First Molars Hyalone, Calcium Hydroxide (Ca(OH)2) Intracanal Medication - Bacterial Load Reduction, Postoperative Pain | Phase 2 | Active not recruiting | Future University in Egypt | 28 | 2026-06-01 | 2026-08-20 |
| N-acetylcysteine for Root Canal Treatment of Necrotic Teeth With Apical Periodontitis Calcium hydroxide (Ca(OH)₂), N-Acetylcysteine (NAC) - Apical Periodontitis | Phase 2 | Active not recruiting | Alexandria University | 40 | 2025-11-15 | 2025-12-30 |
| The Antimicrobial Potential of Diclofenac Sodium as an Intracanal Medicament Diclofenac Sodium, Calcium hydroxide - Endodontic Disease, Pulp Disease, Dental | Phase 2 / Phase 3 | Recruiting | British University In Egypt | 48 | 2025-11-01 | 2025-05-30 |
| Anti-bacterial Potential of Nano Calcium Hydroxide as an Intracanal Medication Calcium hydroxide, nano calcium hydroxide - Endodontic Disease, Pulp Disease, Dental | Phase 2 / Phase 3 | Unknown | British University In Egypt | 54 | 2024-08-01 | 2024-08-19 |
| Evaluation of Silver Diamine Fluoride, Sodium Fluoride With Casein Phosphopeptide-Amorphous Calcium Phosphate(MI Varnish) and Dycal to Arrest Caries When Used in Indirect Pulp Capping Procedures in Children Silver Diamine Fluoride (SDF, 38%) gel, Sodium Fluoride with CPP-ACP (MI varnish), Calcium Hydroxide (CH) - Early Childhood Caries (ECC), Color Stability of Restoration | Phase 2 | Completed | University of Jazan | 90 | 2024-05-06 | 2026-10-26 |
| Investigate"Clinically" the Effectiveness of Boswellia Based Intracanal Medication Compared to Calcium Hydroxide Ca(OH)2 and Ledermix on the Levels of Bacteria and Inflammatory Cytokines in Root Canals and Periradicular Tissues of Teeth With Apical Periodontitis Calcium hydroxide, Leddermix, Boswellia - Microbial Colonization | Phase 2 / Phase 3 | Unknown | Mansoura University | 36 | 2022-06-01 | 2024-06-20 |
| Effectiveness of Glycyrrhizin as Intracanal Medication in Root Canal Disinfection and Inflammatory Cytokines Calcium Hydroxide, Leddermix, Glycirrhizin - Intracanal Medication | Phase 2 / Phase 3 | Unknown | Mansoura University | 36 | 2022-03-20 | 2024-07-03 |
| Evaluation of Antibacterial Effect of Allium Sativum, Calcium Hydroxide and Their Combination in Infected Mature Teeth Allium Sativum, Polymerase chain reaction - Drug Effect | Phase 2 / Phase 3 | Completed | Suez Canal University | 48 | 2019-10-08 | 2021-09-20 |
| Efficacy of PRF and MTA as Compared to Calcium Hydroxide for Pulpotomy in Human Irreversibly Inflamed Permanent Teeth Calcium hydroxide, MTA, PRF - Pulpitis - Irreversible, Tooth Decay | Phase 2 | Completed | Liaquat College of Medicine and Dentistry | 114 | 2019-08-28 | 2022-08-17 |
| Regenerative Endodontic Therapy (RET) for the Management of Immature Non-vital Permanent Teeth in Children RET using antibiotics (Ciprofloxacin and Metronidazole), RET using non-setting Calcium Hydroxide - Infected Immature Permanent Teeth | Phase 2 | Completed | National University Health System, Singapore | 40 | 2017-03-01 | 2021-10-21 |
| Photodynamic Therapy in Endodontic Treatment Laser, Calcium hydroxide - Endodontic Disease | Phase 2 | Completed | Universidade Estadual Paulista Júlio de Mesquita Filho | 24 | 2015-02-01 | 2016-07-06 |
| Comparison Between Biodentine and Calcium Hydroxide in the Indirect Pulp Treatment on Primary Teeth Indirect Pulp Treatment with Bioactive Dentin Substitute, Indirect Pulp treatment with Calcium hydroxide - Dental Caries | Phase 2 / Phase 3 | Unknown | José Arturo Garrocho Rangel | 80 | 2014-11-01 | 2016-06-16 |
| Calcium Hydroxide, Mineral Trioxide Aggregate and Biodentine (Trademark) as Direct Pulp Capping of Permanent Teeth Mineral trioxide aggregate, Calcium hydroxide, Biodentine - Caries, Dental Pulp Exposure | Phase 2 / Phase 3 | Completed | Universidad de los Andes, Chile | 169 | 2014-04-01 | 2024-05-30 |
| Effect Of Different Lining Materials in Stepwise Excavation Control, Calcium Hydroxide, Mineral Trioxide Aggregate(MTA) - Dental Pulp Necrosis | Phase 2 | Unknown | Azad University of Medical Sciences | 100 | 2010-05-01 | 2012-11-21 |
Dental Caries (3) · Dental Pulp Diseases (3) · Pain, Postoperative (2) · Periapical Periodontitis (2) · Communicable Diseases (1) · Dental Pulp Exposure (1) · Dental Pulp Necrosis (1)
British University In Egypt (2) · Mansoura University (2) · Alexandria University (1) · Azad University of Medical Sciences (1) · Future University in Egypt (1) · José Arturo Garrocho Rangel (1) · Liaquat College of Medicine and Dentistry (1) · National University Health System, Singapore (1) · Suez Canal University (1) · Universidad de los Andes, Chile (1) · Universidade Estadual Paulista Júlio de Mesquita Filho (1) · University of Jazan (1)
Egypt (7) · Brazil (1) · Chile (1) · Iran (1) · Pakistan (1) · Saudi Arabia (1) · Singapore (1)
Shehab Eldin M Saber, doctoral (2) · Amany Badr, Prof (1) · Amany Badr, Professor (1) · Claudia Brizuela (1) · Frederico C Martinho, PhD (1) · Ghada Abdelrazik, Dr (1) · Huei Jinn Tong (1) · Sepideh Banava, Assist-Prof (1) · Shaimaa M. Mahfouz, PhD (1) · Youssry Elhawary, Prof (1) · Youssry RM Elhawary, Professor (1)