50 completed, 21 unknown, 7 recruiting, 2 active not recruiting. 29 Not applicable, 25 Phase 4, 14 Phase 2, 9 Phase 1, 6 Phase 3.
Follow Bupivacain: new trials by email Literature Review of Bupivacain trials Research Report on Bupivacain
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparison of Intraperitoneal Bupivacaine and Saline Irrigation for Pain Relief After Laparoscopic Cholecystectomy Bupivacain, Saline (0.9% NaCl) - Postoperative Pain | Phase 4 | Recruiting | Wah Medical college , POF hospital | 106 | 2026-07-01 | 2026-06-16 |
| FASCIA ILIACA BLOCK VERSUS INTRAVENOUS NALBUPHINE AS ANALGESIC METHOD BEFORE POSITIONING FOR SPINAL ANESTHESIA IN PATIENTS UNDERGOING SURGERY FOR HIP FRACTURES Bupivacain, Nalbuphine - Hip Fracture Surgeries | Phase 4 | Active not recruiting | Liaquat National Hospital & Medical College | 30 | 2026-05-12 | 2026-05-29 |
| Comparison Of Clinical Outcomes of Intraperitoneal Bupivacaine Instillation Versus Placebo as Preemptive Analgesia in Patients Undergoing Open Appendectomy Bupivacain, Normal Saline - Appendectomy | Phase 1 | Recruiting | Sardar Umer Rehman | 60 | 2025-12-16 | 2026-02-24 |
| Continuous Epidural With Dexmedetomidine Adjuvant in Gynecologic Laparotomy Dexmedetomidine & Bupivacaine., Bupivacain - Post Operative Pain, Acute, Chronic Post Surgical Pain | Phase 4 | Completed | Udayana University | 62 | 2025-08-21 | 2026-03-25 |
| Superficial Cervical Plexus Block With Dexmedetomidine Versus Without Adjuvant in Thyroid Surgery Dexmedetomidine & Bupivacaine., Bupivacain - Thyroid Cancer, Goiter | Not applicable | Completed | Udayana University | 58 | 2025-07-01 | 2025-12-10 |
| Analgesic Effect of Bupivacaine Plus Ketamine Versus Bupivacaine Alone in Transversalis Fascia Plane Block Ketamine, Bupivacaine, Bupivacain - Analgesia | Phase 1 | Not yet recruiting | Ain Shams University | 68 | 2025-04-25 | 2025-04-20 |
| Phase 2/3 Study of TLC590 for Postsurgical Pain Management TLC590, Bupivacain, Ropivacaine - Postsurgical Pain Management | Phase 2 / Phase 3 | Unknown | Taiwan Liposome Company | 415 | 2025-04-01 | 2024-04-11 |
| Rhomboid Intercostal Sub Serratus Plane Block Versus Serratus Anterior Plane Block in Thoractomy Bupivacain, Ultrasound - Thoracic, Pain | Not applicable | Completed | Yasser S Mostafa, MD | 40 | 2025-02-01 | 2026-10-08 |
| Comparison Between Dexametidomedine\Bupivacaine and Plain Bupivacaine in Superior Trunk Block for Arthroscopic Shoulder Surgeries dexametedomidine, Bupivacain - Post Operative Pain, Acute, Arthroscopic Shoulder Surgery | Not applicable | Completed | Ain Shams University | 40 | 2025-01-20 | 2025-07-01 |
| Role of Pericapsular Nerve Block Using Dexmedetomidine and Bupivacaine in Improving the Outcome of Patients Undergoing Hip Surgery Under Spinal Anesthesia Dexmedetomidin, Bupivacain - Pain During Spinal Positioning | Phase 1 | Completed | Ain Shams University | 60 | 2024-12-10 | 2025-08-29 |
| Vaginal Cuff Anesthesia and Post-Operative Pain Medication Use Bupivacain, Saline (NaCl 0,9 %) (placebo) - Hysterectomy, Post Operative Analgesia | Phase 4 | Recruiting | MediSys Health Network | 100 | 2024-12-01 | 2025-01-07 |
| Effect of Adding Different Concentrations of Dexmedetomidine to Bupivacaine in Caudal Block for Pediatrics Dexmedetomidine, Bupivacain - Caudal Block for Postoperative Analgesia | Phase 1 | Not yet recruiting | Assiut University | 50 | 2024-11-20 | 2024-11-13 |
| Genicular Nerve Block After Open Reduction Internal Fixation of Tibial Plateau Bupivacain - Tibial Plateau Fractures | Phase 1 | Recruiting | University of Chicago | 38 | 2024-11-01 | 2026-02-05 |
| Post-mastectomy Recovery: Comparing Preoperative PECS-II Blocks With Intraoperative Pectoral Blocks Bupivacain, Exparel, Intraoperative Pecs II block (IOB) & superior AT (EX or BP) - Mastectomy; Lymphedema, Breast Cancer | Phase 4 | Recruiting | University of Cincinnati | 100 | 2024-09-25 | 2025-11-04 |
| QL Block in Laparoscopic Myomectomy Bupivacain, Saline - Postoperative Pain, Fibroid Uterus | Phase 4 | Recruiting | Joseph Findley MD | 80 | 2024-08-24 | 2026-09-11 |
| Unilateral Intrathecal Bupivacaine Versus Prilocaine on Postoperative Spontaneous Voiding Prilocaine, Bupivacain - Fast Track Surgery | Phase 4 | Completed | Theodor Bilharz Research Institute | 70 | 2024-08-03 | 2025-12-03 |
| COMPARISON OF BUPIVACAINE WITH AND WITHOUT DEXMEDETOMIDINE IN CAUDAL BLOCK AMONG CHILDREN UNDERGOING INGUINAL HERNIOTOMY Bupivacain, Dexmedetomidine & Bupivacaine. - Pain, Rescue Analgesia | Phase 1 | Completed | Allama Iqbal Medical College | 60 | 2024-08-01 | 2025-08-24 |
| The Effect of Spinal Column Flexion on Unilaterality of Spinal Anesthesia Bupivacain - Hip Fractures, Spinal Anesthesia | Not applicable | Unknown | Ankara City Hospital Bilkent | 60 | 2024-08-01 | 2024-07-31 |
| Comparison of Superior Hypogastric Plexus Block and Peritoneal Bupivacaine in Pain Management Bupivacain, Dexketoprofen (KETAVEL 50 mg/2 ml), Intraperitoneal Bupivacaine spray - Superior Hypogastric Plexus Block, Intraperitoneal Bupivacaine | Completed | Enes Celik | 94 | 2024-07-01 | 2025-05-02 | |
| The Effectiveness of Bupivacaine and Bupivacaine+Dexmedetomidine Combination in Transversus Abdominis Plane* Block Bupivacain, bupivacain+dexmedetomidine - Colorectal Cancer, Colorectal Neoplasms | Completed | Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital | 84 | 2024-05-01 | 2026-07-02 |
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Pain, Postoperative (35) · Agnosia (14) · Pain (10) · Hip Fractures (3) · Breast Neoplasms (2) · Goiter (2) · Aortic Aneurysm, Abdominal (1) · Aortic Diseases (1) · Arthritis (1) · Atrial Fibrillation (1) · Back Pain (1) · Balanitis (1) · Cardiac Output, Low (1) · Cardiac Septal Defects with Coarctation of the Aorta (1) · Carpal Tunnel Syndrome (1)
Ain Shams University (8) · Assiut University (5) · Benha University (4) · Istanbul University (3) · Sohag University (3) · Armed Forces Hospital, Pakistan (2) · Cukurova University (2) · Dr. Lutfi Kirdar Kartal Training and Research Hospital (2) · Icahn School of Medicine at Mount Sinai (2) · Minia University (2) · Sisli Hamidiye Etfal Training and Research Hospital (2) · Udayana University (2) · Alberta Children's Hospital (1) · Alexandria University (1) · Allama Iqbal Medical College (1)
Egypt (27) · Turkey (Türkiye) (14) · United States (14) · Pakistan (7) · Indonesia (2) · Sweden (2) · Argentina (1) · Canada (1) · Denmark (1) · Panama (1) · Spain (1) · Syria (1) · Taiwan (1) · Tunisia (1)
Fatma Ah Abdelfatah, MD (2) · Fouad I Soliman, MD (2) · Albert Sundberg, MD, PhD (1) · Ali Shariat, M.D. (1) · Angel Oliva Pascual-Vaca, Dr (1) · Anthony Christiano, MD (1) · Asmaa Ah Hossain, Ph.D (1) · Beyza Seker, MD (1) · Bryce Weber, MD FRCSC (1) · Chad A. Purnell, MD (1) · Christina Gunnervik, MD (1) · Dilek MD Metin Yamac (1) · Dina Salem, MD. (1)
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