4 completed, 1 withdrawn. 5 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 4, Withdrawn 1 |
| Phase 3 | 1 | Completed 1 |
Follow Biotin: new trials by email Literature Review of Biotin trials Research Report on Biotin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Biotin-Acridine Red Cell Exchange Kinetics Pathogen reduced red blood cells - Sickle Cell Disease | Phase 2 | Withdrawn | Cerus Corporation | 2025-10-15 | 2026-09-22 | |
| Safety and Tolerability of High Dose Biotin in Patients With Amyotrophic Lateral Sclerosis Biotin, Placebo Oral Tablet - Amyotrophic Lateral Sclerosis | Phase 2 | Completed | American University of Beirut Medical Center | 12 | 2018-01-29 | 2021-09-01 |
| SERENDEM : MD1003 in Patients Suffering From Demyelinating Neuropathies, an Open Label Pilot Study MD1003 - Chronic Inflammatory Demyelinating Polyneuropathy, Peripheral Neuropathy | Phase 2 | Completed | MedDay Pharmaceuticals SA | 15 | 2016-12-05 | 2020-11-02 |
| Effect of MD1003 in Amyotrophic Lateral Sclerosis MD1003, Placebo oral capsule - ALS, Amyotrophic Lateral Sclerosis | Phase 2 | Completed | MedDay Pharmaceuticals SA | 30 | 2016-06-29 | 2019-06-04 |
| MD1003-AMN MD1003 in Adrenomyeloneuropathy MD1003 100 mg capsule, Placebo - Adrenomyeloneuropathy, Adrenoleukodystrophy | Phase 2 / Phase 3 | Completed | MedDay Pharmaceuticals SA | 67 | 2014-10-01 | 2017-10-09 |
Amyotrophic Lateral Sclerosis (2) · Adrenoleukodystrophy (1) · Anemia, Sickle Cell (1) · Charcot-Marie-Tooth Disease (1) · Motor Neuron Disease (1) · Peripheral Nervous System Diseases (1) · Polyradiculoneuropathy, Chronic Inflammatory Demyelinating (1)
MedDay Pharmaceuticals SA (3) · American University of Beirut Medical Center (1) · Cerus Corporation (1)
France (3) · Germany (1) · Lebanon (1) · Spain (1)
Frederic Sedel, MD (2) · Achraf Makki, MD (1) · Johnny Salameh, MD (1) · Patrick Aubourg, MD (1)
PMID 11750036, PMID 17182796, PMID 19192301, PMID 19268425, PMID 22714021, PMID 23039386, PMID 23217177, PMID 25787192, PMID 27589059, PMID 32140672, PMID 37899433