4 completed, 2 unknown, 1 not yet recruiting. 3 Not applicable, 2 Phase 2, 1 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Completed 1, Not yet recruiting 1, Unknown 1 |
| Phase 2 | 2 | Completed 2 |
| Phase 3 | 1 | Unknown 1 |
| Phase 4 | 1 | Completed 1 |
Follow Bicarbonate: new trials by email Literature Review of Bicarbonate trials Research Report on Bicarbonate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dial-Bicarb Trial: Effects of a Lower vs. Higher Concentration of Dialysate Bicarbonate Bicarbonate - Renal Failure, Hemodialysis | Not applicable | Not yet recruiting | McMaster University | 14000 | 2025-04-01 | 2025-03-20 |
| The Effects of Ankaferd Blood Stopper Ankaferd Blood Stopper, Bicarbonate - Colon Cancer, Oral Mucositis | Not applicable | Unknown | Uludag University | 66 | 2021-06-01 | 2023-06-01 |
| Alkalinization by Urologists & Nephrologists Alkali - Metabolic Acidosis, Nephrolithiasis | Phase 4 | Completed | Jean-Philippe Bertocchio | 156 | 2017-02-01 | 2020-07-14 |
| Pilot Study to Investigate the Effects of Increased Dialysate Magnesium and Dialysate Bicarbonate on the Calcification Propensity of Serum Magnesium, Bicarbonate - End Stage Renal Failure on Dialysis, Vascular Calcification | Not applicable | Completed | Insel Gruppe AG, University Hospital Bern | 12 | 2015-12-01 | 2017-09-26 |
| Correction of Metabolic Acidosis in End Stage Renal Disease (ESRD) Bicarbonate - Metabolic Acidosis | Phase 3 | Unknown | Azienda Sanitaria ASL Avellino 2 | 728 | 2014-07-01 | 2014-09-19 |
| Prevention of Acute Kidney Injury in Cardiac Surgery Patients 0.9% Sodium Chloride (Placebo), Sodium Bicarbonate - Kidney Injury | Phase 2 | Completed | Community Medical Center, Scranton, PA | 92 | 2009-01-01 | 2014-04-15 |
| Use of Bicarbonate to Reduce the Incidence of Acute Renal Failure After Cardiac Surgery Sodium bicarbonate, Normal saline, Bicarbonate - Kidney Failure, Acute, Renal Replacement Therapy | Phase 2 | Completed | Wake Forest University Health Sciences | 123 | 2006-05-01 | 2018-10-16 |
Acidosis (2) · Acute Kidney Injury (2) · Body Weight (1) · Colonic Neoplasms (1) · Colorectal Neoplasms (1) · Nephrolithiasis (1) · Renal Insufficiency (1) · Stomatitis (1) · Vascular Calcification (1)
Azienda Sanitaria ASL Avellino 2 (1) · Community Medical Center, Scranton, PA (1) · Insel Gruppe AG, University Hospital Bern (1) · Jean-Philippe Bertocchio (1) · McMaster University (1) · Uludag University (1) · Wake Forest University Health Sciences (1)
United States (2) · France (1) · Italy (1) · Switzerland (1) · Turkey (Türkiye) (1)
Amit Garg, MD (1) · Biagio Di Iorio, MD, PhD (1) · Dominik Uehlinger, Prof Dr.med. (1) · Judith L Kristeller, PharmD (1) · Julie Beaume, MD (1) · Michael V. Rocco, MD (1)
PMID 16041502, PMID 18304416, PMID 23553549, PMID 24854326, PMID 25596649, PMID 27770799, PMID 31286226, PMID 31598912, PMID 31631858, PMID 34564842, PMID 37289263, PMID 9659518