3 terminated, 1 completed, 1 unknown, 1 withdrawn. 6 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 6 | Terminated 3, Completed 1, Unknown 1, Withdrawn 1 |
Follow bezlotoxumab: new trials by email Literature Review of bezlotoxumab trials Research Report on bezlotoxumab
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Bezlotoxumab Versus FMT for Multiple Recurrent CDI Bezlotoxumab, Fecal Microbiota Transplantation (FMT), Vancomycin oral - Clostridium Infections, Clostridioides Difficile | Phase 4 | Withdrawn | Leiden University Medical Center | 2022-01-01 | 2023-03-28 | |
| Prevention of Recurrent Clostridium Difficile Infection (CDI) in Patients With Inflammatory Bowel Disease (IBD). Bezlotoxumab - Inflammatory Bowel Diseases, Ulcerative Colitis | Phase 4 | Terminated | David Binion, MD | 19 | 2021-10-14 | 2025-06-05 |
| Bezlotoxumab Efficacy and Tolerability in Cancer Patient Bezlotoxumab Injection - Clostridium Difficile Infection Recurrence | Phase 4 | Unknown | The Cooper Health System | 132 | 2020-07-01 | 2020-06-04 |
| Bezlotoxumab as Secondary Prophylaxis for C. Difficile in High-risk Hospitalized Patients Exposed to Antibiotics. Bezlotoxumab - Clostridium Difficile | Phase 4 | Terminated | Montefiore Medical Center | 1 | 2019-08-30 | 2022-11-09 |
| Comparing the Effectiveness of IV Bezlotoxumab Versus Placebo in Decreasing Morbidity and Mortality in Patients With Fulminant C. Diff Requiring Surgery. Bezlotoxumab, Normal Saline - Clostridia Difficile Colitis, Clostridium; Sepsis | Phase 4 | Terminated | Ohio State University | 5 | 2019-08-19 | 2026-06-18 |
| Bezlotoxumab (BEZLO) In Addition To Standard Of Care (SOC) Vancomycin For The Treatment of Multi-Recurrent Clostridium Difficile Infection bezlotoxumab, Vancomycin Oral - Clostridium Difficile Infection Recurrence | Phase 4 | Completed | University of Kansas Medical Center | 4 | 2019-06-25 | 2022-05-26 |
Clostridium Infections (2) · Enterocolitis, Pseudomembranous (2) · Colitis, Ulcerative (1) · Crohn Disease (1) · Diarrhea (1) · Inflammatory Bowel Diseases (1) · Recurrence (1) · Sepsis (1)
David Binion, MD (1) · Leiden University Medical Center (1) · Montefiore Medical Center (1) · Ohio State University (1) · The Cooper Health System (1) · University of Kansas Medical Center (1)
United States (4) · Netherlands (1)
David Binion, MD (1) · J van Prehn (1) · Lisa A Clough, MD (1) · Paul Riska, MD (1)
2019 (1)