8 unknown, 5 completed, 1 terminated. 14 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 14 | Unknown 8, Completed 5, Terminated 1 |
Follow ATG: new trials by email Literature Review of ATG trials Research Report on ATG
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Study of rATG Individualized Administration in Haploidentical Hematopoietic Stem Cell Transplantation Individual ATG, ATG - Hematopoietic Stem Cell Transplantation, Acute Leukemia | Phase 4 | Unknown | The First Affiliated Hospital of Soochow University | 90 | 2022-12-20 | 2023-02-15 |
| ATG in HLA-matched Sibling HSCT as GVHD Prophylaxis ATG, CsA, MTX - Hematopoietic Stem Cell Transplantation | Phase 4 | Unknown | Nanfang Hospital, Southern Medical University | 266 | 2019-09-01 | 2019-12-18 |
| Hematopoietic Stem Cell Transplantation for Patients With Thalassemia Major: A Multicenter, Prospective Clinical Study Busulfan, Cyclophosphamide, Fludarabine - Thalassemia Major | Phase 4 | Completed | First Affiliated Hospital of Guangxi Medical University | 823 | 2019-07-05 | 2024-08-09 |
| PTCy-ATG vs ATG in Haploidentical HSCT for Acute Graft-versus-host Disease Prophylaxis ATG, CTX, Mycophenolate Mofetil - Hematopoietic Stem Cell Transplantation | Phase 4 | Unknown | Nanfang Hospital, Southern Medical University | 260 | 2018-10-29 | 2019-10-28 |
| ATG/PTCy in Haplo-PBSCT Randomized Controlled,Multi-center ATG/PTCy, standard ATG, standard PTCy - Myeloid Tumor | Phase 4 | Completed | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | 418 | 2018-07-28 | 2023-10-05 |
| Observational Study to Evaluate the Safety and Efficacy of Polyclonal Antibodies in Simultaneous Pancreas Kidney Transplant Recipients Anti-Tlymphocyte Globulins, Anti-Thymocyte Globulins - CKD (Chronic Kidney Disease) Stage 5T, Diabetes Mellitus | Phase 4 | Unknown | Tianjin First Central Hospital | 45 | 2018-03-01 | 2018-03-20 |
| A Optimal Anti-Thymoglobuline (ATG) Dose Decrease cGVHD But Not Increase Leukemia Relapse for Haplo-HSCT ATG - Chronic Graft-versus-host-disease, Leukemia Relapse | Phase 4 | Unknown | Zhujiang Hospital | 192 | 2017-08-30 | 2017-06-19 |
| Haploidentical Hematopoietic Stem Cell Transplantation for Patients With Thalassemia Major Busulfan, Cyclophosphamide, Fludarabine - Thalassemia Major | Phase 4 | Unknown | First Affiliated Hospital of Guangxi Medical University | 30 | 2017-04-01 | 2017-05-31 |
| Efficacy and Safety Study of ATG for Prophylaxis of aGVHD in Matched Sibling Donor PBSCT ATG, CsA, mycophenolate mofetil - aGVHD | Phase 4 | Completed | Chinese PLA General Hospital | 100 | 2016-01-01 | 2022-05-24 |
| Single Dose rATG for Renal Allograft Rejection rATG - Acute (Cellular) Renal Allograft Rejection | Phase 4 | Unknown | The Methodist Hospital Research Institute | 30 | 2014-03-01 | 2020-09-03 |
| ATG in Haploidentical HSCT for Acute Graft-versus-host Disease Prophylaxis ATG - Hematopoietic Stem Cell Transplantation, Antithymocyte Globulin | Phase 4 | Completed | Nanfang Hospital, Southern Medical University | 412 | 2013-06-01 | 2018-04-24 |
| Everolimus + Very Low Tacrolimus vs Enteric-coated Mycophenolate Sodium + Low Tacrolimus in de Novo Renal Transplant Everolimus, Very Low Tacrolimus, Low Tacrolimus - Transplantation Infection, Cytomegalovirus Infections | Phase 4 | Completed | Ronaldo de Matos Esmeraldo, MD | 120 | 2012-12-01 | 2019-02-22 |
| De Novo Everolimus-based Therapy for Renal Transplantation Using Rituximab Induction rituximab and everolimus, thymoglobulin and tacrolimus - Renal Insufficiency | Phase 4 | Terminated | National Taiwan University Hospital | 2 | 2011-04-01 | 2012-12-27 |
| Different Doses of Anti-thymocyte Globin to Treat Child Severe Aplastic Anemia ATG - Severe Aplastic Anemia | Phase 4 | Unknown | Chinese Academy of Medical Sciences | 100 | 2010-12-01 | 2013-12-03 |
Graft vs Host Disease (2) · Virus Diseases (2) · beta-Thalassemia (2) · Anemia, Aplastic (1) · Bronchiolitis Obliterans Syndrome (1) · Cytomegalovirus Infections (1) · Diabetes Mellitus (1) · Renal Insufficiency (1) · Renal Insufficiency, Chronic (1)
Nanfang Hospital, Southern Medical University (3) · First Affiliated Hospital of Guangxi Medical University (2) · Chinese Academy of Medical Sciences (1) · Chinese PLA General Hospital (1) · National Taiwan University Hospital (1) · Ronaldo de Matos Esmeraldo, MD (1) · Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine (1) · The First Affiliated Hospital of Soochow University (1) · The Methodist Hospital Research Institute (1) · Tianjin First Central Hospital (1) · Zhujiang Hospital (1)
China (10) · Brazil (1) · Taiwan (1) · United States (1)
Qifa Liu (2) · Yongrong Lai, MD (2) · Bingyi Wu, MD (1) · Daihong Liu, Doctor (1) · MK Tsai, MD, PhD (1) · Qifa Liu, MD (1) · Ronaldo M Esmeraldo, MD (1) · Samir Patel, PharmD (1) · Xiaowen Tang, PhD (1) · Yingxin FU, M.D (1)
PMID 37341189, PMID 1090310, PMID 15814548, PMID 27855166, PMID 29969826, PMID 31401973, PMID 32164760, PMID 33663084, PMID 35467818, PMID 41730859, PMID 41849227