7 completed, 3 terminated. 10 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 10 | Completed 7, Terminated 3 |
| Phase 1 | 1 | Completed 1 |
Follow Alefacept: new trials by email Literature Review of Alefacept trials Research Report on Alefacept
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Inducing Remission in Type 1 Diabetes With Alefacept Alefacept, Placebo - New-onset Type 1 Diabetes Mellitus | Phase 2 | Terminated | National Institute of Allergy and Infectious Diseases (NIAID) | 49 | 2011-03-01 | 2017-07-06 |
| Alefacept in Subjects With Steroid-Refractory Chronic Graft-versus-Host Disease Alefacept - Chronic Graft-versus-host Disease | Phase 2 | Terminated | Dana-Farber Cancer Institute | 6 | 2010-10-01 | 2013-08-13 |
| Safety and Pharmacokinetics (PK) of Alefacept in Adolescent Subjects With Moderate to Severe Psoriasis alefacept - Psoriasis | Phase 2 | Completed | Astellas Pharma Inc | 30 | 2009-04-01 | 2013-12-12 |
| A Study to Assess the Safety and Efficacy of Alefacept in Kidney Transplant Recipients Alefacept, tacrolimus, basiliximab - Kidney Transplantation | Phase 2 | Completed | Astellas Pharma Inc | 323 | 2008-02-01 | 2015-12-11 |
| A Study to Assess the Efficacy and Safety of Alefacept in Kidney Transplant Recipients Alefacept, placebo, Tacrolimus - De Novo Kidney Transplantation | Phase 2 | Completed | Astellas Pharma Inc | 218 | 2007-12-01 | 2016-02-04 |
| Alefacept for Chronic Graft Versus Host Disease Alefacept - Resistant Chronic GVHD | Phase 1 / Phase 2 | Completed | Hadassah Medical Organization | 20 | 2006-10-01 | 2015-04-21 |
| Open-Label,Singel Center Study of Alefacept in Patients With Atopic Dermatitis Alefacept - Atopic Dermatitis | Phase 2 | Completed | Insel Gruppe AG, University Hospital Bern | 10 | 2006-01-01 | 2007-12-10 |
| Study to Evaluate the Efficacy of Alefacept to Treat Palmar Plantar Pustulosis Alefacept - Psoriasis, Palmoplantaris Pustulosis | Phase 2 | Completed | The Guenther Dermatology Research Centre | 15 | 2005-06-01 | 2006-11-23 |
| A Safety and Efficacy Study of Alefacept in the Treatment of Moderate to Severe Erosive Mucosal Lichen Planus Amevive (Alefacept), Placebo - Lichen Planus | Phase 2 | Terminated | Massachusetts General Hospital | 13 | 2004-04-01 | 2009-02-12 |
| A Placebo-controlled Study With an Extension Examining the Safety and Efficacy of Alefacept in Psoriatic Arthritis Alefacept, Methotrexate, Placebo - Psoriatic Arthritis | Phase 2 | Completed | Astellas Pharma Inc | 185 | 2003-09-01 | 2014-09-18 |
Psoriasis (3) · Arthritis, Psoriatic (1) · Autoimmune Diseases (1) · Bronchiolitis Obliterans Syndrome (1) · Dermatitis, Atopic (1) · Lichen Planus (1)
Astellas Pharma Inc (4) · Dana-Farber Cancer Institute (1) · Hadassah Medical Organization (1) · Insel Gruppe AG, University Hospital Bern (1) · Massachusetts General Hospital (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · The Guenther Dermatology Research Centre (1)
United States (6) · Canada (2) · Germany (2) · Poland (2) · Austria (1) · Belgium (1) · Bulgaria (1) · Czechia (1) · France (1) · Hungary (1) · Israel (1) · Italy (1) · Latvia (1) · Netherlands (1) · Russia (1)
Alexandra B. Kimball, MD, MPH (1) · Corey Cutler, MD (1) · Lyn C Guenther, MD, FRCPC (1) · Mark R Rigby, MD, PhD (1) · Michael Y Shapira, MD (1) · Nikhil Yawalkar, Prof (1)
PMID 24622414, PMID 26193635, PMID 27208317
2008 (1)