16 completed, 2 terminated, 1 not yet recruiting, 1 recruiting. 21 Phase 1, 10 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 21 | Completed 16, Terminated 2, Not yet recruiting 1, Recruiting 1, Withdrawn 1 |
| Phase 2 | 10 | Completed 8, Not yet recruiting 1, Withdrawn 1 |
Follow Adrucil: new trials by email Literature Review of Adrucil trials Research Report on Adrucil
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Stereotactic Body Radiation Therapy Followed by NALIRIFOX vs NALIRIFOX for Borderline Resectable Pancreatic Cancer Irinotecan liposome injection, Oxaliplatin, 5-Fluorouracil - Pancreatic Cancer | Phase 1 / Phase 2 | Not yet recruiting | Tianjin Medical University Cancer Institute and Hospital | 96 | 2024-04-01 | 2024-03-15 |
| FOLFIRINOX + NIS793 in Pancreatic Cancer FOLFIRINOX, Oxaliplatin, Leucovorin - Pancreas Cancer, Metastatic Pancreatic Cancer | Phase 1 | Terminated | Colin D. Weekes, M.D., PhD | 4 | 2022-08-09 | 2025-11-18 |
| Liposomal Irinotecan Plus 5-FU / LV Combined With Paricalcitol in Patients With Advanced Pancreatic Cancer Progressed on Gemcitabine-based Therapy 5-FU, Leucovorin, Liposomal Irinotecan - Pancreatic Cancer, Pancreas Cancer | Phase 1 | Completed | Washington University School of Medicine | 20 | 2019-07-11 | 2022-10-05 |
| Intralesional 5-Fluorouracil (5FU), Topical Calcipotriene Treatment for SCC 5-fluorouracil, Calcipotriene - Carcinoma, Squamous Cell | Phase 1 | Recruiting | Melissa Pugliano-Mauro | 30 | 2018-08-03 | 2026-06-01 |
| BATS With in Combination With Low Dose IL-1 and GM-CSF for Advanced Pancreatic Cancer Aldesleukin, Antibody Therapy, Fluorouracil - Metastatic Pancreatic Adenocarcinoma, Recurrent Pancreatic Carcinoma | Phase 1 / Phase 2 | Completed | Barbara Ann Karmanos Cancer Institute | 2 | 2015-12-01 | 2023-05-15 |
| Modufolin (Arfolitixorin) in Combination With 5-Fluorouracil Alone or Together With Oxaliplatin or Irinotecan in Colorectal Cancer Modufolin (arfolitixorin), Fluorouracil, Oxaliplatin - Colorectal Neoplasm | Phase 1 / Phase 2 | Completed | Isofol Medical AB | 105 | 2014-09-01 | 2020-09-09 |
| A Study of BBI608 in Combination With Standard Chemotherapies in Adult Patients With Pancreatic Cancer BBI608, Nab-paclitaxel, Gemcitabine - Metastatic Pancreatic Adenocarcinoma | Phase 1 | Completed | Sumitomo Pharma America, Inc. | 139 | 2014-08-01 | 2023-11-18 |
| S1313, PEGPH20 in Treating Patients With Newly Diagnosed Metastatic Pancreatic Cancer PEGPH20, Oxaliplatin, Leucovorin - Metastatic Pancreatic Adenocarcinoma | Phase 1 / Phase 2 | Completed | SWOG Cancer Research Network | 126 | 2014-01-23 | 2024-02-09 |
| A Study of BBI608 in Combination With Standard Chemotherapies in Adult Patients With Advanced Gastrointestinal Cancer BBI608, Fluorouracil, Oxaliplatin - Advanced Gastrointestinal Cancer | Phase 1 / Phase 2 | Completed | Sumitomo Pharma America, Inc. | 495 | 2014-01-01 | 2023-11-15 |
| Study to Evaluate Safety & Tolerability of BMS-906024 in Combination With Chemotherapy & to Define DLTs & MTD of BMS-906024 in Combination With One of the Following Chemotherapy Regimens; Weekly Paclitaxel, 5FU+Irinotecan or Carboplatin+Paclitaxel in Subjects With Advanced / Metastatic Solid Tumors Paclitaxel, 5-Fluorouracil (5FU), Carboplatin - Cancer | Phase 1 | Completed | Bristol-Myers Squibb | 141 | 2012-10-12 | 2020-01-28 |
| Everolimus and Combination Chemotherapy in Treating Patients With Metastatic Stomach or Esophageal Cancer fluorouracil, leucovorin calcium, oxaliplatin - Adenocarcinoma of the Esophagus, Adenocarcinoma of the Gastroesophageal Junction | Phase 1 / Phase 2 | Completed | City of Hope Medical Center | 6 | 2012-02-01 | 2017-05-31 |
| Radiolabeled Monoclonal Antibody Therapy, Combination Chemotherapy, and Bevacizumab in Treating Patients With Metastatic Colorectal Cancer irinotecan hydrochloride, leucovorin calcium, fluorouracil - Recurrent Colon Cancer, Recurrent Rectal Cancer | Phase 1 | Completed | City of Hope Medical Center | 3 | 2011-08-30 | 2026-10-16 |
| Safety and Clinical Pharmacology of GDC-0068 in Combination With Docetaxel, Fluoropyrimidine Plus Oxaliplatin, Paclitaxel, or Enzalutamide in Participants With Advanced Solid Tumors 5-FU, Docetaxel, Enzalutamide - Neoplasms | Phase 1 | Completed | Genentech, Inc. | 122 | 2011-07-11 | 2022-01-12 |
| Trimodality Management of T1b Esophageal Cancers Docetaxel, 5-FU, Radiotherapy - Esophageal Cancer | Phase 1 / Phase 2 | Completed | M.D. Anderson Cancer Center | 4 | 2010-10-01 | 2021-04-13 |
| Panobinostat and Fluorouracil Followed By Leucovorin Calcium in Treating Patients With Stage IV Colorectal Cancer Who Did Not Respond to Previous Fluorouracil-Based Chemotherapy panobinostat, fluorouracil, leucovorin calcium - Recurrent Colon Cancer, Recurrent Rectal Cancer | Phase 1 | Terminated | University of Southern California | 7 | 2010-10-01 | 2015-05-27 |
| Lenalidomide in Combination With Bevacizumab, Sorafenib, Temsirolimus, or 5-Fluorouracil, Leucovorin, Oxaliplatin (FOLFOX) Lenalidomide, Bevacizumab, Sorafenib - Advanced Cancers | Phase 1 | Completed | M.D. Anderson Cancer Center | 180 | 2010-08-01 | 2016-06-03 |
| Hepatic Arterial Infusion Oxaliplatin + 5FU, Leucovorin, and Bevacizumab +/- Cetuximab HAI Oxaliplatin, 5-FU, Bevacizumab - Advanced Cancers | Phase 1 | Completed | M.D. Anderson Cancer Center | 140 | 2009-07-01 | 2015-11-18 |
| Hepatic Arterial Infusion of Oxaliplatin, Fluorouracil, Leucovorin, and Avastin Fluorouracil, Avastin, Leucovorin - Liver Cancer, Advanced Solid Tumors | Phase 1 | Completed | M.D. Anderson Cancer Center | 63 | 2006-06-01 | 2012-07-30 |
| Docetaxel, 5-Fluorouracil and Oxaliplatin in Adenocarcinoma of the Stomach or Gastroesophageal Junction Patients 5-Fluorouracil, Docetaxel, Oxaliplatin - Gastrointestinal Diseases | Phase 1 / Phase 2 | Completed | M.D. Anderson Cancer Center | 98 | 2004-08-01 | 2016-10-31 |
| Fluorouracil and Low-Dose Suramin as Chemosensitization in Treating Patients With Metastatic Renal Cell (Kidney) Cancer Fluorouracil, Pharmacological Study, Suramin - Recurrent Renal Cell Carcinoma, Stage IV Renal Cell Cancer | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 36 | 2004-03-01 | 2015-05-25 |
Showing 20 of 21. Sign in to see all of them.
Pancreatic Neoplasms (7) · Colonic Neoplasms (4) · Rectal Neoplasms (3) · Stomach Neoplasms (3) · Carcinoma, Renal Cell (2) · Carcinoma, Squamous Cell (2) · Colorectal Neoplasms (2) · Esophageal Neoplasms (2) · Gastrointestinal Diseases (2) · Neoplasms (2) · Adenocarcinoma (1) · Adenocarcinoma Of Esophagus (1) · Adenoma, Islet Cell (1) · Breast Neoplasms (1) · Carcinoma (1)
M.D. Anderson Cancer Center (5) · City of Hope Medical Center (2) · Sumitomo Pharma America, Inc. (2) · Barbara Ann Karmanos Cancer Institute (1) · Bristol-Myers Squibb (1) · Colin D. Weekes, M.D., PhD (1) · Genentech, Inc. (1) · Isofol Medical AB (1) · Melissa Pugliano-Mauro (1) · National Cancer Institute (NCI) (1) · Roswell Park Cancer Institute (1) · SWOG Cancer Research Network (1) · Tianjin Medical University Cancer Institute and Hospital (1) · University of Southern California (1) · Washington University School of Medicine (1)
United States (19) · Canada (2) · Belgium (1) · Denmark (1) · France (1) · Greece (1) · Norway (1) · Spain (1) · Sweden (1) · United Kingdom (1)
Apostolia M. Tsimberidou, MD, PhD (2) · Anthony Shields (1) · Apostolia M. Tsimberidou, MD, PHD (1) · Boston Biomedical (1) · Colin D Weekes, MD, PHD (1) · Daniel Maslyar, M.D. (1) · Heinz-Josef Lenz (1) · Jaffer Ajani, MD (1) · Jeffrey Wong, MD (1) · Jihui Hao, Professor (1) · Kian-Huat Lim, M.D, Ph.D. (1) · Melissa Pugliano-Mauro, MD (1) · Ramesh K Ramanathan, M.D. (1)
PMID 23756764, PMID 26908161, PMID 30817250, PMID 32205017, PMID 32939319, PMID 33099678, PMID 36183444
2014 (1), P30CA016056 (1), P30CA022453 (1), P50CA121973 (1), R01CA093871 (1), U01CA062502 (1), U10CA180888 (1)